Methyl 1H-indole-7-carboxylate
- CAS No.
- 93247-78-0
- Chemical Name:
- Methyl 1H-indole-7-carboxylate
- Synonyms
- RARECHEM AL BF 0640;Methyl 1H-indole-7-c;Methyl1H-indole-7-carboxyl;Methyl(7-indolecarboxylate);METHYL INDOLE-7-CARBOXYLATE;7-(Methoxycarbonyl)-1H-indole;METHYL 1H-INDOLE-7-CARBOXYLATE;7-INDOLECARBOXYLIC ACID METHYL ESTER;INDOLE-7-CARBOXYLIC ACID METHYL ESTER;1H-INDOLE-7-CARBOXYLIC ACID METHYL ESTER
- CBNumber:
- CB1474204
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD00211064
- MOL File:
- 93247-78-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Methyl(7-indolecarboxylate) for synthesis | 8.43864 | 1g | $211 |
| Methyl indole-7-carboxylate Asreported | 284641 | 2g | $333 |
| Methyl indole-7-carboxylate Asreported | 284641 | 5g | $503 |
| Methyl indole-7-carboxylate Asreported | 284641 | 10g | $685 |
| Methyl indole-7-carboxylate Asreported | 284641 | 25g | $981 |
| More product size | |||
| Melting point | 47-48°C |
|---|---|
| Boiling point | 331.7±15.0 °C(Predicted) |
| Density | 1.253±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 15.42±0.30(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C10H9NO2/c1-13-10(12)8-4-2-3-7-5-6-11-9(7)8/h2-6,11H,1H3 |
| InChIKey | FTLOEULOTNVCGF-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2C(OC)=O)C=C1 |
| CAS DataBase Reference | 93247-78-0(CAS DataBase Reference) |
| UNSPSC Code | 12352108 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-37/39 | |||||||||
| WGK Germany | WGK 3 highly water endangering | |||||||||
| HS Code | 2933 99 80 | |||||||||
| HazardClass | IRRITANT | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
Methyl 1H-indole-7-carboxylate price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.43864 | Methyl(7-indolecarboxylate) for synthesis | 93247-78-0 | 1g | $211 | 2023-01-07 | Buy |
| Usbiological | 284641 | Methyl indole-7-carboxylate Asreported | 93247-78-0 | 2g | $333 | 2026-06-03 | Buy |
| Usbiological | 284641 | Methyl indole-7-carboxylate Asreported | 93247-78-0 | 5g | $503 | 2026-06-03 | Buy |
| Usbiological | 284641 | Methyl indole-7-carboxylate Asreported | 93247-78-0 | 10g | $685 | 2026-06-03 | Buy |
| Usbiological | 284641 | Methyl indole-7-carboxylate Asreported | 93247-78-0 | 25g | $981 | 2026-06-03 | Buy |
Methyl 1H-indole-7-carboxylate Chemical Properties,Uses,Production
Uses
Methyl Indole-7-carboxylate is useful for the preparation of inhibitors of CD38, which are useful in the treatment of cancer.
Synthesis
67-56-1
1670-83-3
93247-78-0
To a solution of 1H-indole-7-carboxylic acid (20 g, 124 mmol, 1.0 eq.) in methanol (700 ml) was slowly added concentrated sulfuric acid (1.2 g, 12 mmol, 0.1 eq.), the temperature of the reaction system was maintained at 0 °C and stirring was continued. The reaction mixture was heated to reflux and maintained for 20 hours. After completion of the reaction, methanol was evaporated under reduced pressure using a rotary evaporator. The residue was dissolved in ethyl acetate and the organic phase was washed sequentially with saturated sodium carbonate solution and brine. The organic layer was dried over anhydrous sodium sulfate and filtered, and the filtrate was concentrated under reduced pressure to give Intermediate 1 (16.3 g, 75% yield) as a yellow solid.
References
[1] Patent: WO2013/4709, 2013, A1. Location in patent: Page/Page column 51
Methyl 1H-indole-7-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
View Lastest Price from Methyl 1H-indole-7-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | Methyl 1H-indole-7-carboxylate
93247-78-0
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
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2020-06-02 | Methyl 1H-indole-7-carboxylate in stock Factory
93247-78-0
|
$1.00 | 1KG | TOP 3 Factory in China | Chemwill Asia Co.,Ltd. | ||
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|
2020-06-02 | Methyl 1H-indole-7-carboxylate in stock Factory
93247-78-0
|
$1.00 | 1KG | TOP 3 Factory in China | Chemwill Asia Co.,Ltd. |
-
- Methyl 1H-indole-7-carboxylate
93247-78-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- Methyl 1H-indole-7-carboxylate in stock Factory
93247-78-0
- $1.00
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- Methyl 1H-indole-7-carboxylate in stock Factory
93247-78-0
- $1.00
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
