Sodium thiomethoxide
- CAS No.
- 5188-07-8
- Chemical Name:
- Sodium thiomethoxide
- Synonyms
- SODIUM METHANETHIOLATE;NaSMe;SODIUM METHYL MERCAPTIDE;Sodium methylthiolate;METHYL MERCAPTAN SODIUM SALT;thioformate;Sodium thiomethylate;SODIUM METHYLMERCAPTAN;Sodium methanethiol;SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM)
- CBNumber:
- CB1476576
- Molecular Formula:
- CH3NaS
- Molecular Weight:
- 70.09
- MDL Number:
- MFCD00174316
- MOL File:
- 5188-07-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Sodium thiomethoxide 95% | 281018 | 1g | $51.5 |
| Sodium thiomethoxide 95% | 281018 | 5g | $137 |
| Methyl Mercaptan Sodium Salt (ca. 15% in Water) | M0096 | 25g | $38 |
| Methyl Mercaptan Sodium Salt (ca. 15% in Water) | M0096 | 500g | $144 |
| Sodium Methanethiolate 95+% ≥95% | 466297 | 2.5g | $432 |
| More product size | |||
| Density | 1.12[at 20℃] |
|---|---|
| vapor pressure | 29hPa at 25℃ |
| Flash point | 27°C |
| storage temp. | Air and moisture sensitive. Store under inert gas. Sensitive to carbon dioxide Exposure to moisture. |
| solubility | soluble in Water |
| form | Powder |
| color | White to off-white |
| Water Solubility | soluble |
| Merck | 14,5956 |
| BRN | 3592983 |
| InChI | InChI=1S/CH4S.Na/c1-2;/h2H,1H3;/q;+1/p-1 |
| InChIKey | RMBAVIFYHOYIFM-UHFFFAOYSA-M |
| SMILES | CS[Na] |
| LogP | -2.33 at 20℃ |
| CAS DataBase Reference | 5188-07-8(CAS DataBase Reference) |
| FDA UNII | LB29JWW8H7 |
| EPA Substance Registry System | Methanethiol, sodium salt (5188-07-8) |
| UNSPSC Code | 12352103 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302-H314 | |||||||||
| Precautionary statements | P210-P280-P301+P312+P330-P301+P330+P331-P303+P361+P353-P305+P351+P338+P310 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C,F | |||||||||
| Risk Statements | 31-34-20/21/22-11-35-25-10 | |||||||||
| Safety Statements | 26-36/37/39-45-16 | |||||||||
| RIDADR | UN 3263 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 1-34-10-13 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 4.3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 4.1B - Flammable solid hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 3 Oral Flam. Sol. 1 Skin Corr. 1A |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
Sodium thiomethoxide price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 281018 | Sodium thiomethoxide 95% | 5188-07-8 | 1g | $51.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 281018 | Sodium thiomethoxide 95% | 5188-07-8 | 5g | $137 | 2026-04-30 | Buy |
| TCI Chemical | M0096 | Methyl Mercaptan Sodium Salt (ca. 15% in Water) | 5188-07-8 | 25g | $38 | 2026-04-30 | Buy |
| TCI Chemical | M0096 | Methyl Mercaptan Sodium Salt (ca. 15% in Water) | 5188-07-8 | 500g | $144 | 2026-04-30 | Buy |
| Usbiological | 466297 | Sodium Methanethiolate 95+% ≥95% | 5188-07-8 | 2.5g | $432 | 2026-06-03 | Buy |
Sodium thiomethoxide Chemical Properties,Uses,Production
Description
Sodium methanethiolate or sodium thiomethoxide (CH3SNa, MeSNa) is the sodium conjugate base of methanethiol. This compound is commercially available as a white solid. Sodium Methanethiolate is used as a nucleophile in organic synthesis. This compound is also being used as a reagent to synthesize thiol-based suberoylanilide hydroxamic acid (SAHA) analogues, compounds that act as potent histone deacetylase inhibitors. It reacts with trifluoroacetic acid and water to produce the active form of sodium trifluoroacetate. The reaction mechanism is likely due to the formation of a bicyclic heterocycle that has been shown to be effective against a number of bacteria.
Chemical Properties
Very faint yellowish red clear liquid
Uses
Sodium thiomethoxide is a strong nucleophile used for the synthesis of methyl aryl sulfides from halo-arenes. Alkanethiolates are efficient reagents for SN2 dealkylation of esters and aryl ethers.
Uses
Used to prepare a C-21 thioether of methyl 16-prednisolonecarboxylate by mesylate displacement.
Reactivity Profile
Sodium thiomethoxide is a powerful nucleophile that can be used to prepare methylthioether and other organic compounds like ethyl bromide. Its hydrolysis in moist air produces methanethiol, which has a low odor threshold and a noxious fecal smell.
reaction suitability
core: sodium
Purification Methods
Dissolve the salt (10g) in EtOH (10mL) and add Et2O (100mL). Cool and collect the precipitate, wash it with Et2O and dry it in a vacuum. It is a white powder which is very soluble in EtOH and H2O. [Billmann & Jensen Bull Soc Chim Fr 3 2318 1936, Beilstein 1 III 1212.]
Sodium thiomethoxide Preparation Products And Raw materials
Raw materials
Preparation Products
1of5
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +8617792793228 | 1069@dideu.com | China | 8661 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
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View Lastest Price from Sodium thiomethoxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-15 | Sodium thiomethoxide
5188-07-8
|
$1.50 | 1g | 99.0% Min | 10 Tons | Shaanxi Didu New Materials Co. Ltd | |
 |
2026-03-20 | Sodium thiomethoxide
5188-07-8
|
$10.00 | 1kg | 99.5% | 100 | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-10-29 | Sodium thiomethoxide
5188-07-8
|
1kg | 99 | 20tons | Chongqing Chemdad Co., Ltd |
-
- Sodium thiomethoxide
5188-07-8
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-
- Sodium thiomethoxide
5188-07-8
- $10.00
- 99.5%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Sodium thiomethoxide
5188-07-8
- 99
- Chongqing Chemdad Co., Ltd
