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Borussertib

Borussertib structure

CAS No.: 1800070-77-2

Chemical Name:: Borussertib

Synonyms: Borussertib;Borussertib, 10 mM in DMSO;Borussertib,Inhibitor,PKB,Akt,Protein kinase B,inhibit;2-Propenamide, N-[3-[1-[[4-(5,6-dihydro-5-oxo-3-phenyl-1,6-naphthyridin-2-yl)phenyl]methyl]-4-piperidinyl]-2,3-dihydro-2-oxo-1H-benzimidazol-5-yl]-

CBNumber:: CB14844579

Molecular Formula:: C36H32N6O3

Molecular Weight:: 596.68

MDL Number:: MFCD32062807

MOL File:: 1800070-77-2.mol

Last updated:2025-05-13 19:34:56

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Borussertib Properties

Density	1.318±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 25 mg/mL (41.90 mM; Need ultrasonic)
pka	10.74±0.20(Predicted)
form	Solid
color	White to off-white

Borussertib price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0090402	Borussertib 98.59%	1800070-77-2	5mg	$350	2021-12-16	Buy
ChemScene	CS-0090402	Borussertib 98.59%	1800070-77-2	10mg	$550	2021-12-16	Buy
ChemScene	CS-0090402	Borussertib 98.59%	1800070-77-2	25mg	$990	2021-12-16	Buy
DC Chemicals	DC21869	Borussertib >98%	1800070-77-2	250mg	$1500	2021-12-16	Buy
DC Chemicals	DC21869	Borussertib >98%	1800070-77-2	1g	$3000	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0090402	5mg	$350	Buy
CS-0090402	10mg	$550	Buy
CS-0090402	25mg	$990	Buy
DC21869	250mg	$1500	Buy
DC21869	1g	$3000	Buy

Borussertib Chemical Properties,Uses,Production

Uses

Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt[1].

References

[1] Niklas Uhlenbrock, et al. Structural and chemical insights into the covalentallosteric inhibition of the protein kinase Akt. Chem Sci., 2019, 10, 3573.

Borussertib Preparation Products And Raw materials

Raw materials

Preparation Products

Borussertib Suppliers

Global( 36)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32268	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38663	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	sales@meilune.com	China	4730	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4611	55

Supplier	Advantage
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
BOC Sciences	65
Dalian Meilun Biotech Co., Ltd.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55

View Lastest Price from Borussertib manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-05-13	Borussertib 1800070-77-2	US $135.00-455.00 / mg		99.00%	10g	TargetMol Chemicals Inc.

Borussertib
1800070-77-2
US $135.00-455.00 / mg
99.00%
TargetMol Chemicals Inc.

Borussertib 2-Propenamide, N-[3-[1-[[4-(5,6-dihydro-5-oxo-3-phenyl-1,6-naphthyridin-2-yl)phenyl]methyl]-4-piperidinyl]-2,3-dihydro-2-oxo-1H-benzimidazol-5-yl]- Borussertib,Inhibitor,PKB,Akt,Protein kinase B,inhibit Borussertib, 10 mM in DMSO 1800070-77-2