Sulfanilic acid
- CAS No.
- 121-57-3
- Chemical Name:
- Sulfanilic acid
- Synonyms
- SULPHANILIC ACID;4-AMINOBENZENESULFONIC ACID;sulfanilic;P-AMINOBENZENESULFONIC ACID;4-aminobenzenesulfonate;SULFANILLIC ACID;Sulphanillic Acid;ANILINE-4-SULFONIC ACID;SULFANILIC ACID ANHYD PWD;4-AMINOBENZENESULPHONIC ACID
- CBNumber:
- CB1489237
- Molecular Formula:
- C6H7NO3S
- Molecular Weight:
- 173.19
- MDL Number:
- MFCD00007886
- MOL File:
- 121-57-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Sulfanilic acid for synthesis | 8.22338 | 100g | $37.1 |
| Sulfanilic acid for synthesis | 8.22338 | 1kg | $100 |
| Sulfanilic acid for synthesis | 8.22338 | 50kg | $1140 |
| Sulfanilic acid ACS reagent, 99% | 251917 | 25g | $36.7 |
| Nitrate Reagent B suitable for microbiology | 39441 | 100mL | $51.2 |
| More product size | |||
| Melting point | >300 °C(lit.) |
|---|---|
| Boiling point | 288 ℃ |
| bulk density | 620kg/m3 |
| Density | 1.485 |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5500 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | 10g/l |
| pka | 3.24(at 25℃) |
| form | solid |
| color | White to Off-White |
| PH | 2.5 (10g/l, H2O, 20℃) |
| Water Solubility | 0.1 g/100 mL (20 ºC) |
| Merck | 14,8926 |
| BRN | 908765 |
| Henry's Law Constant | 1.1×107 mol/(m3Pa) at 25℃, HSDB (2015) |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChI | 1S/C6H7NO3S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H,8,9,10) |
| InChIKey | HVBSAKJJOYLTQU-UHFFFAOYSA-N |
| SMILES | Nc1ccc(cc1)S(O)(=O)=O |
| LogP | -2.3 at 25℃ |
| Indirect Additives used in Food Contact Substances | SULFANILIC ACID |
| CAS DataBase Reference | 121-57-3(CAS DataBase Reference) |
| FDA 21 CFR | 176.180 |
| FDA UNII | 434Z8C2635 |
| NIST Chemistry Reference | Benzenesulfonic acid, 4-amino-(121-57-3) |
| EPA Substance Registry System | Sulfanilic acid (121-57-3) |
| UNSPSC Code | 41171621 |
| NACRES | NB.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H317-H412 | |||||||||
| Precautionary statements | P501-P261-P273-P272-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P333+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 36/38-43-34 | |||||||||
| Safety Statements | 26-36/37/39-45-37-24-36/37 | |||||||||
| RIDADR | UN 2790 8/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | WP3895500 | |||||||||
| Autoignition Temperature | >400 °C | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29214210 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 |
|||||||||
| Hazardous Substances Data | 121-57-3(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: 12300 mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Sulfanilic acid price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.22338 | Sulfanilic acid for synthesis | 121-57-3 | 100g | $37.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.22338 | Sulfanilic acid for synthesis | 121-57-3 | 1kg | $100 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.22338 | Sulfanilic acid for synthesis | 121-57-3 | 50kg | $1140 | 2026-04-30 | Buy |
| Sigma-Aldrich | 251917 | Sulfanilic acid ACS reagent, 99% | 121-57-3 | 25g | $36.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 39441 | Nitrate Reagent B suitable for microbiology | 121-57-3 | 100mL | $51.2 | 2026-04-30 | Buy |
Sulfanilic acid Chemical Properties,Uses,Production
Synthesize
Sulfanilic acid can be used for the determination of nitrite. Biochemical Research. Organic Synthesis. Sulfanilic acid is an important intermediate of sulfonamide drugs. This product has strong antibacterial effect on hemolytic streptococcus, meningitis and coccus, but due to poor efficacy and high toxicity, it is rarely used for oral administration. It is also rarely used. It is used as an intermediate for the synthesis of other sulfonamides, and is also used as a raw material for the synthesis of agricultural "Huangcaoling" abroad. Sulfanilic acid can also be used as an analytical reagent, such as a reagent for the photometric determination of nitrite and sodium nitroferricyanide. For biochemical research, organic synthesis and pharmaceutical industry. Sulfanilic acid is the main raw material for synthesizing sulfonamides. In addition to preparing crystalline sulfonamides for external anti-inflammatory, it can also synthesize other sulfonamides such as sulfamidine, sulfamethoxazine, and sulfamethazine.
Description
Sulfanilic acid (4-amino benzene sulfonic acid ) is an off-white crystalline solid which finds application in quantitative analysis of nitrate and nitrite ions. The solid acid exists as a zwitterion, and has an unusually high melting point.
Chemical Properties
greyish-white crystals or powder
Uses
A toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.
Uses
Sulfanilic Acid (Sulfadimethoxine EP Impurity D) is a toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.
Uses
Sulfanilic acid may be used for the functionalization of single-walled carbon nanotubes (SWNTs) with aryl sulfonate groups.
Definition
ChEBI: An aminobenzenesulfonic acid that is aniline sulfonated at the para-position.
Application
As the compound readily form diazo compounds, it is used to make dyes and sulpha drugs . This property is also used for the quantitative analysis of nitrate and nitrite ions by diazonium coupling reaction with N-(1-Naphthyl) ethylene diamine , resulting in an azo dye, and the concentration of nitrate or nitrite ions were deduced from the color intensity of the resulting red solution by colorimetry.
It is also used as a standard in combustion analysis.
General Description
White powder with faint purple tinge. Grayish-white flat crystals. Becomes anhydrous at around 212°F. Low toxicity (used medicinally).
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Sulfanilic acid is an amino acid. Reacts weakly with both acids and bases.
Fire Hazard
Flash point data for Sulfanilic acid are not available, however Sulfanilic acid is probably combustible.
Synthesis
Sulfanilic acid can be produced by sulfonation of aniline.
Purification Methods
Crystallise the acid (as dihydrate) from boiling water. Dry it at 105o for 2-3hours, then over 90% H2SO4 in a vacuum desiccator. The S-benzylisothiuronium salt has m 187o (from aqueous EtOH). [Beilstein 14 IV 2655.]
Sulfanilic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of8
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5233 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Tianjin Zhongxin Chemtech Co., Ltd. | 86-22-66880623 +8618622897568 | sales@tjzxchem.com | China | 572 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29816 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
Related articles
- Uses of Sulfanilic acid
- Sulfanilic acid (SA) is a typical representative compound of sulfonated aromatic amines and an intermediate in some sulfonated....
- Dec 16，2024
- Synthetic method of sulfanilic acid
- Sulfanilic acid, also known as p-aminobenzenesulfonamide, with the molecular formula C6H8N2O2S, is an organic compound with me....
- Mar 25，2022
View Lastest Price from Sulfanilic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-22 | Sulfanilic acid
121-57-3
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-03-20 | Sulfanilic acid
121-57-3
|
US $1.00 / KG | 1KG | 99% | 10mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-11-18 | Sulfanilic acid
121-57-3
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- Sulfanilic acid
121-57-3
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Sulfanilic acid
121-57-3
- US $1.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Sulfanilic acid
121-57-3
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
