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Pentoxyverine

CAS No.
77-23-6
Chemical Name:
Pentoxyverine
Synonyms
PENTOXIFYLLINE;Carbetapentane;Urex;Tuclase;Pentoxyverine Base;ucb2543;Atussil;Sedotussin;u.c.b.2543;U.C.B. 2543
CBNumber:
CB1497317
Molecular Formula:
C20H31NO3
Molecular Weight:
333.46
MDL Number:
MFCD00209899
MOL File:
77-23-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:37:19

Pentoxyverine Properties

Boiling point 165-170 °C (1.33Pa)
Density 1.048±0.06 g/cm3(Predicted)
refractive index 1.4990-1.5010
storage temp. Refrigerator
solubility Dichloromethane (Slightly), Methanol (Slightly)
pka 9.69±0.25(Predicted)
form Oil
color Clear Very Dark Red to Brown
CAS DataBase Reference 77-23-6(CAS DataBase Reference)
FDA UNII 32C726X12W
ATC code R05DB05
NIST Chemistry Reference 1-Cyclopentanecarboxylate, 2-(diethylaminoethoxy)ethyl-1-phenyl-(77-23-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazardous Substances Data 77-23-6(Hazardous Substances Data)
Toxicity LD50 oral in rat: 150mg/kg

Pentoxyverine price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-C178025-50MG Carbetapentane 77-23-6 50mg $195 2026-06-03 Buy
TRC TRC-C178025-100MG Carbetapentane 77-23-6 100mg $299 2026-06-03 Buy
ChemScene CS-0136428 Pentoxyverine 98.91% 77-23-6 5mg $35 2026-06-04 Buy
ChemScene CS-0136428 Pentoxyverine 98.91% 77-23-6 10mg $54 2026-06-04 Buy
ChemScene CS-0136428 Pentoxyverine 98.91% 77-23-6 25mg $97 2026-06-04 Buy
Product number Packaging Price Buy
TRC-C178025-50MG 50mg $195 Buy
TRC-C178025-100MG 100mg $299 Buy
CS-0136428 5mg $35 Buy
CS-0136428 10mg $54 Buy
CS-0136428 25mg $97 Buy

Pentoxyverine Chemical Properties, Uses, Production

Chemical Properties

Oily substance. Boiling point 165-170℃ (1.33Pa), refractive index 1.4990-1.5010.

Originator

Asthma ,Nichiiko

Uses

Carbetapentane is an antitussive anticonvulsant sigma site agonist.

Definition

ChEBI: 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester is a member of benzenes.

Manufacturing Process

1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.
1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.
1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.
A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.

brand name

Toclase (Pfizer).

Therapeutic Function

Antitussive

Global Suppliers ( 123)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Cantotech Chemicals, Ltd. 86-0755-86635001 cantotech@126.com China 4554 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Hubei widely chemical technology Co., Ltd. 027-83991130 18627774460 1718093273@QQ.COM China 1617 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Wuhai Shuou Technology Co., Ltd. 17792809151;18872220797 2355916837@ycphar.com China 6120 55

View Latest Price from Pentoxyverine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pentoxyverine Citrite pictures 2026-09-18 Pentoxyverine Citrite
77-23-6
1KG 99%min 1000KG WUHAN FORTUNA CHEMICAL CO., LTD
Pentoxyverine USP/EP/BP pictures 2026-08-20 Pentoxyverine USP/EP/BP
77-23-6
$1.10 1g 99.9% 100Tons min Dideu Industries Group Limited
Pentoxyverine pictures 2026-04-22 Pentoxyverine
77-23-6
$29.00 97.11% 10g TargetMol Chemicals Inc.
1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester 1-phenyl-1-cyclopentanecarboxylate 1-Phenylcyclopentane-1-Carboxylic acid diethylaminoethoxyethyl ester 1-phenylcyclopentane-1-carboxylicaciddiethylaminoethoxyethylester 1-phenyl-cyclopentanecarboxylicaci2-(2-(diethylamino)ethoxy)ethylester 1-phenylcyclopentanecarboxylicacid2-(2-diethylaminoethoxy)ethylester ucb2543 Urex Pentoxyverine Base CARETAPENTANE Carbetapentane (base and/or unspecified salts) PENTOXIFYLLINE 2-(2-DIETHYLAMINOETHOXY)ETHYL 1-PHENYLCYCLOPENTANECARBOXYLATE CITRATE 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane 1-Phenylcyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethyloxy)ethyl ester 2-(2-diethylaminoethyloxy)ethyl 1-phenylcyclopentane-1-carboxylate 2-(2-Diethylaminoethoxy)ethyl 1-phenylcyclopentane-1-carboxylate PENTOSYVERINECITRATE Pentoxyverine citrate (Carbetapentane) 2-(2-Diethylaminoethoxy)ethyl 1-phenylcyclopentanecarboxylate 2-(2-diethylaminoethoxy)ethyl1-phenylcyclopentanecarboxylate 2-(Diethylaminoethoxy)ethyl 1-phenyl-1-cyclopentanecarboxylate 2-(Diethylaminoethoxy)ethyl 1-phenylcyclopentyl-1-carboxylate 2-(diethylaminoethoxy)ethyl1-phenyl-1-cyclopentanecarboxylate 2-(diethylaminoethoxy)ethyl1-phenylcyclopentyl-1-carboxylate 2-[2-(Diemthylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylate Atussil Cyclopentanecarboxylic acid, 1-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester Ethanol, 2-[2-(diethylamino)ethoxy]-, 1-phenylcyclopentanecarboxylate (ester) Pentoxiverin Pentoxiverine Pentoxyverin Pentoxyverine Sedotussin Tuclase U.C.B. 2543 u.c.b.2543 Pentoxyverine USP/EP/BP Pentoxyverine Citrite Cough will clear Pentoxyverine Monomer Carbetapentane 77-23-6 C26H39NO10 Miscellaneous Biochemicals