DIHYDROFOLATE REDUCTASE F. BOVINE LIVER, ~8 U/MG, 500 UL
- CAS No.
- 9002-03-3
- Chemical Name:
- DIHYDROFOLATE REDUCTASE F. BOVINE LIVER, ~8 U/MG, 500 UL
- Synonyms
- Dihydrofolate Reductase bovine liver;dihydrofolate reductase F. bovine liver;DIHYDROFOLATE REDUCTASEFROM CHICKEN LIVE R;Dihydrofolate Reductase from bovine liver;5,6,7,8-Tetrahydrofolate: NADP+ oxidoreductase;Dihydrofolate Reductase solution from chicken liver;DIHYDROFOLATE REDUCTASE F. BOVINE LIVER, ~8 U/MG, 500 UL
- CBNumber:
- CB1502596
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130955
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|
DIHYDROFOLATE REDUCTASE F. BOVINE LIVER, ~8 U/MG, 500 UL Chemical Properties,Uses,Production
Uses
Dihydrofolate reductase is a key enzyme in folate metabolism and, therefore, in the production of thymidine. Its role in thymidine biosynthesis is the reduction of dihydrofolate to tetrahydrofolate using the cofactor NADPH[1].
Purification Methods
Dihydrofolate reductase is purified by (NH4)2SO4 precipitation, then fractionation on a Sephadex G-75 column, applied to a Blue Sepharose column and eluted with 1mM dihydrofolate. [Al Rubeai & Dole Biochem J 235 301 1986.]
References
[1] Hongnan Cao, et al. The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release. Commun Biol. 2018 Dec 12:1:226. DOI:10.1038/s42003-018-0236-y
DIHYDROFOLATE REDUCTASE F. BOVINE LIVER, ~8 U/MG, 500 UL Preparation Products And Raw materials
Raw materials
Preparation Products
DIHYDROFOLATE REDUCTASE F. BOVINE LIVER, ~8 U/MG, 500 UL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
| Supplier | Advantage |
|---|---|
| Biosynth Biological Technology (Suzhou) Co Ltd | 58 |
