Bak (D2D3) Rabbit mAb
- CAS No.
- Chemical Name:
- Bak (D2D3) Rabbit mAb
- Synonyms
- Bak (D2D3) Rabbit mAb
- CBNumber:
- CB15607252
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Bak (D2D3) Rabbit mAb Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human;Monkey
Background
Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.
References
[1] Gross, A. et al. (1999) Genes Dev. 13, 1899-1911.
[2] Wei, M.C. et al. (2001) Science 292, 727-730.
[3] Zong, W.X. et al. (2001) Genes Dev. 15, 1481-1486.
[4] Degenhardt, K. et al. (2002) J. Biol. Chem. 277, 14127-14134.
[5] Wei, M.C. et al. (2000) Genes Dev. 14, 2060-2071.
Bak (D2D3) Rabbit mAb Preparation Products And Raw materials
Raw materials
Preparation Products
Bak (D2D3) Rabbit mAb Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cell Signaling Technology Inc | -- | info@cellsignal.cn | China | 6725 | 58 |
| Guangzhou Keda Heng New Technology Co., Ltd. | -- | CHINA | 6139 | 58 | |
| Guangzhou Chengjin Biotechnology Co., Ltd. | -- | CHINA | 1340 | 58 | |
| Suzhou Ruinuode Biotechnology Co., Ltd. | -- | 2090855807@qq.com | CHINA | 6247 | 58 |
| Shanghai Haoran Biotechnology Co., Ltd. | -- | 470003480@QQ.COM | CHINA | 6935 | 58 |
| Beijing Dongge Boye Biotechnology Co., Ltd. | -- | 1861586486@qq.com | CHINA | 6643 | 58 |
| Shanghai Gaochuang Chemical Technology Co., Ltd. | -- | gaochem@163.com | CHINA | 6991 | 58 |
| Beijing Zhongbei Linge Technology Development Co., Ltd. | -- | bjzblg@126.com | CHINA | 2631 | 58 |
| Beijing Fubo Biotechnology Co., Ltd. | -- | info@f-biology.com | CHINA | 6147 | 58 |
| Beijing Huaxia Ocean Technology Co., Ltd. | -- | huaxiabio@163.com | CHINA | 6119 | 58 |
