HSF, 1 antibody

CAS No.
Chemical Name:
HSF, 1 antibody
Synonyms
HSF, 1 antibody
CBNumber:
CB15635707
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

HSF, 1 antibody price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biorbyt Ltd orb572494 HSF1 Antibody 50μl $230 2026-05-06 Buy
Biorbyt Ltd orb572494 HSF1 Antibody 100μl $370 2026-05-06 Buy
Biorbyt Ltd orb572302 HSF1 Antibody 100μl $380 2026-05-06 Buy
Biorbyt Ltd orb572289 HSF1 Antibody 100μl $380 2026-05-06 Buy
Biorbyt Ltd orb571034 HSF1 Antibody 50μg $140 2026-05-06 Buy
Product number Packaging Price Buy
orb572494 50μl $230 Buy
orb572494 100μl $370 Buy
orb572302 100μl $380 Buy
orb572289 100μl $380 Buy
orb571034 50μg $140 Buy

HSF, 1 antibody Chemical Properties, Uses, Production

Source

Rabbit

Applications

HSF1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:1,000~ 2,000. Recommended starting dilution is 1:1,000.

Reactivity

Human;Mouse;Rat;Monkey

Immunogen

Anti-human HSF1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSF1 amino acids 1-529 purified from E. coli.

Background

The transcription of heat-shock genes is rapidly induced after temperature stress in response to environmental changes, and it is also involved in oogenesis, spermatogenesis, and placental development. Hsp90, is a major repressor of HSF1 gene. HSF1 is known for its participation in heat shock response. HSF1 protein regulates the transcription of hundreds of targets, such as genes involved in protein folding, detoxification, energy generation, carbohydrate metabolism, and cell wall organization. HSF1 binds to MTA1 in vitro & in breast carcinoma. Suppression of estrogen-dependent transcription may contribute to role of HSF1 in cancer. Human cancer lines of diverse origins express higher dependence on HSF1 function to maintain proliferation and survival than their non-transformed counterparts. HSF1 induces anticoagulation and relaxation factors in vascular endothelial cells and could therefore be used to treat cardiovascular disease. HSF1 is directly involved in the regulation of HO1 havi

References

[1] Morimoto, R.I. (1998) Genes Dev 12, 3788-96.
[2] Mercier, P.A. et al. (1999) J Cell Sci 112 ( Pt 16), 2765-74.
[3] Kim, S.A. et al. (2005) J Biol Chem 280, 12653-7.
[4] Holmberg, C.I. et al. (2001) EMBO J 20, 3800-10.
[5] Chu, B. et al. (1996) J Biol Chem 271, 30847-57.
[6] Wang, X. et al. (2003) Mol Cell Biol 23, 6013-6.
[7] Satyal, S.H. et al. (1998) Genes Dev 12, 1962-74.

HSF, 1 antibody Preparation Products And Raw materials

Raw materials

Preparation Products

HSF, 1 antibody Suppliers

Global Suppliers ( 107)
Supplier Tel Email Country ProdList Advantage
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25030 58
Hubei Ipodix Biotechnology Co.,Ltd. 18007124176 19384116026 2706668885@qq.com China 4987 58
HSF, 1 antibody