ChemicalBook >> CAS DataBase List >>FAPI-4
FAPI-4
- CAS No.
- 2374782-02-0
- Chemical Name:
- FAPI-4
- Synonyms
- FAPI;FAPI04;187366;FAPI-4;G-1002;DOTA-FAPI4;DOTA-FAPI 04;FAPI-4 Chemical Structure;1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-;(S)-2,2’,2’’-[10-[2-[4-[3-[[4-[[2-(2-Cyano-4,4-difluoro-1-pyrrolidinyl)-2-oxoethyl]carbamoyl]-6-quinolyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetic Acid
- CBNumber:
- CB15849362
- Molecular Formula:
- C40H54F2N10O10
- Molecular Weight:
- 872.93
- MDL Number:
- MFCD32067986
- MOL File:
- 2374782-02-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-08-05 09:01:00
| Boiling point | 1144.1±65.0 °C(Predicted) |
|---|---|
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 100 mg/mL (114.56 mM) |
| pka | 1.83±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| InChIKey | ICWDAESAANBIGG-NNFJEGBSNA-N |
| SMILES | C(C1=CC=NC2C=CC(OCCCN3CCN(C(=O)CN4CCN(CCN(CC(=O)O)CCN(CC(=O)O)CC4)CC(=O)O)CC3)=CC1=2)(=O)NCC(N1CC(F)(F)C[C@H]1C#N)=O |&1:58,r| |
| FDA UNII | D7X5DKW7N9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
FAPI-4 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | ZUD78202 | FAPI-4 | 2374782-02-0 | 5mg | $897.5 | 2026-06-05 | Buy |
| Biosynth | ZUD78202 | FAPI-4 | 2374782-02-0 | 10mg | $1435.9 | 2026-06-05 | Buy |
| Biosynth | ZUD78202 | FAPI-4 | 2374782-02-0 | 25mg | $2341.5 | 2026-06-05 | Buy |
| Biosynth | ZUD78202 | FAPI-4 | 2374782-02-0 | 50mg | $3746 | 2026-06-05 | Buy |
| ChemScene | CS-0096318 | FAPI-4 99.47% | 2374782-02-0 | 1mg | $338 | 2026-06-04 | Buy |
FAPI-4 Chemical Properties, Uses, Production
Uses
FAPI-4 is a substituted pyrrolidinyloxoethyl quinolinecarboxamides and one type of theranostic ligand for fibroblast activation protein (FAP). FAPI-4 is a FAP inhibitor (FAPI) and has been studied for its pharmaceutical properties in the diagnose or treatment of diseases driven by the overexpression of FAPs.
in vivo
FAPI-4 (Intravenous injection; 30 nmol per mouse; once) shows excellent tumor uptake in BALB/c nu/nu mice[2].
| Animal Model: | 8-week-old BALB/c nu/nu mice inoculated with HT-1080-FAP cells[2] |
| Dosage: | 30 nmol per mouse |
| Administration: | Intravenous injection; 30 nmol per mouse; once |
| Result: | Revealed the high overall tumor uptake (9.44%ID/g 4 h after injection). |
FAPI-4 Preparation Products And Raw materials
Raw materials
Preparation Products
FAPI-4 Suppliers
Global Suppliers ( 50)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Baige Pharmaceutical Technology Co. , Ltd. | 0571-85350119 15888826472 | 15888826472@163.com | China | 2728 | 58 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| YangZhou Ruihong Biotech Co., Ltd. | 0514-015380367604 15380367604 | sales@ruibobiotech.com | China | 509 | 55 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9780 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Rhawn Reagent | 400-400-1332688 18019345275 | huyue@rhawn.cn | China | 14942 | 58 |
2374782-02-0 (FAPI-4) Related Search:
FAPI-4
187366
(S)-2,2',2''-(10-(2-(4-(3-((4-((2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy)propyl)piperazin-1-yl)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid
(S)-2,2’,2’’-[10-[2-[4-[3-[[4-[[2-(2-Cyano-4,4-difluoro-1-pyrrolidinyl)-2-oxoethyl]carbamoyl]-6-quinolyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetic Acid
G-1002
FAPI-4 Chemical Structure
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]-
DOTA-FAPI4
DOTA-FAPI 04
FAPI04
FAPI
2374782-02-0
C40H54F2N10O10
