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ChemicalBook >> CAS DataBase List >>8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Structure
8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol structure
CAS No.
117811-17-3
Chemical Name:
8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol
Synonyms
Desloratadine Dehydro 11-Hydroxy N-Methyl Impurity;8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol;8-chloro-11-(1-methylpiperidin-4-yl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol;11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-11-(1-methyl-4-piperidinyl)-
CBNumber:
CB15992741
Molecular Formula:
C20H21ClN2O
Molecular Weight:
340.85
MDL Number:
MOL File:
117811-17-3.mol
Last updated:2023-05-15 10:44:02
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8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Properties

Boiling point 509.8±50.0 °C(Predicted)
Density 1.267±0.06 g/cm3(Predicted)
solubility soluble in Dichloromethane
pka 11.94±0.20(Predicted)
form Solid
color Yellow

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Chemical Properties,Uses,Production

Uses

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is an intermediate in synthesizing Ethyl 4-(8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate (E902775). It is an impurity of loratadine (L469575), which is a nonsedating-type histamine H1-receptor.

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Preparation Products And Raw materials

Raw materials

Preparation Products

8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Suppliers

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QUALITY CONTROL SOLUTIONS LTD. 		58
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Hubei Yangxin Medical Technology Co., Ltd. 55
Nanjing wangzhixing Pharmaceutical Technology Co., Ltd 58
Huaihua Yuanyanda Biotechnology Co., Ltd 58
Shanghai YuZn Pharm. Technology Co.,Ltd. 58
Huaihua Yuanyanda Biotechnology Co., Ltd 58
8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Desloratadine Dehydro 11-Hydroxy N-Methyl Impurity 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-11-(1-methyl-4-piperidinyl)- 8-chloro-11-(1-methylpiperidin-4-yl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol 117811-17-3