ChemicalBook >> CAS DataBase List >>5-Trans prostaglandin d2

5-Trans prostaglandin d2

CAS No.
2202725-84-4
Chemical Name:
5-Trans prostaglandin d2
Synonyms
5-Trans prostaglandin d2;9α,15S-dihydroxy-11-oxo-prosta-5E,13E-dien-1-oicacid;9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5E,13E-DIEN-1-OIC ACID
CBNumber:
CB1664582
Molecular Formula:
C20H32O5
Molecular Weight:
352.47
MDL Number:
MFCD03411988
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:49:20

5-Trans prostaglandin d2 Properties

solubility DMF: 100 mg/ml
DMSO: 50 mg/ml
Ethanol: 75 mg/mlPBS (pH 7.2): 5 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
NFPA 704
0
2 0

5-Trans prostaglandin d2 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 12210 5-trans Prostaglandin D2 ≥98% 2202725-84-4 1mg $68 2026-04-30 Buy
Cayman Chemical 12210 5-trans Prostaglandin D2 ≥98% 2202725-84-4 5mg $291 2026-04-30 Buy
Cayman Chemical 12210 5-trans Prostaglandin D2 ≥98% 2202725-84-4 10mg $515 2026-04-30 Buy
Product number Packaging Price Buy
12210 1mg $68 Buy
12210 5mg $291 Buy
12210 10mg $515 Buy

5-Trans prostaglandin d2 Chemical Properties,Uses,Production

Description

PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells, including mast cells and basophils, by leukocyte-type PGD synthase.1,2 5-trans PGD2 is an isomer of PGD2 wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of prostaglandin D2 (PGD2) occurs as an impurity between 2-5% in most commercial preparations of the bulk drug product. This compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type prostaglandins, the biological activity of 5-trans PGD2 is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity of 5-trans PGD2.WARNING This product is not for human or veterinary use.

References

[1] I MAHMUD. Prostaglandin D synthase in human megakaryoblastic cells.[J]. The Journal of Biological Chemistry, 1997, 272 45: 28263-28266. DOI: 10.1074/jbc.272.45.28263
[2] MAYUMI UJIHARA . Prostaglandin D2 formation and characterization of its synthetases in various tissues of adult rats[J]. Archives of biochemistry and biophysics, 1988, 260 2: Pages 521-531. DOI: 10.1016/0003-9861(88)90477-8

5-Trans prostaglandin d2 Preparation Products And Raw materials

Raw materials

Preparation Products

5-Trans prostaglandin d2 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5E,13E-DIEN-1-OIC ACID 9α,15S-dihydroxy-11-oxo-prosta-5E,13E-dien-1-oicacid 5-Trans prostaglandin d2 2202725-84-4