3-Aminobenzenesulfonanilide
- CAS No.
- 80-21-7
- Chemical Name:
- 3-Aminobenzenesulfonanilide
- Synonyms
- Metanilanilide;3-Aminosulfonanilide;3-Aminobenzene sulfanilide;3-AMINOBENZENESULFONANILIDE;m-aminobenzenesulphonanilide;3-aminobenzenesulphonanilide;M-AMINO BENZENE SULFONANILIDE;3-[(4-Aminophenyl)sulfonyl]aniline;3-amino-n-phenyl-benzenesulfonamid;3-azanyl-N-phenyl-benzenesulfonamide
- CBNumber:
- CB1669648
- Molecular Formula:
- C12H12N2O2S
- Molecular Weight:
- 248.3
- MDL Number:
- MFCD00035928
- MOL File:
- 80-21-7.mol
- MSDS File:
- SDS
| storage temp. | 2-8°C(protect from light) |
|---|---|
| CAS DataBase Reference | 80-21-7(CAS DataBase Reference) |
| FDA UNII | TB92UA8FRX |
| EPA Substance Registry System | Benzenesulfonamide, 3-amino-N-phenyl- (80-21-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| TSCA | TSCA listed |
3-Aminobenzenesulfonanilide price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00G24X | 3-Amino-N-phenylbenzenesulfonamide 98%(HPLC) | 80-21-7 | 1g | $22 | 2026-05-28 | Buy |
| aablocks | AA00G24X | 3-Amino-N-phenylbenzenesulfonamide 98%(HPLC) | 80-21-7 | 5g | $54 | 2026-05-28 | Buy |
| aablocks | AA00G24X | 3-Amino-N-phenylbenzenesulfonamide 98% | 80-21-7 | 10g | $96 | 2026-05-28 | Buy |
| aablocks | AA00G24X | 3-Amino-N-phenylbenzenesulfonamide 98%(HPLC) | 80-21-7 | 25g | $156 | 2026-05-28 | Buy |
| aablocks | AA00G24X | 3-Amino-N-phenylbenzenesulfonamide 98%(HPLC) | 80-21-7 | 100g | $389 | 2026-05-28 | Buy |
3-Aminobenzenesulfonanilide Chemical Properties, Uses, Production
Synthesis
28791-26-6
80-21-7
Preparation of 3-amino-N-phenylbenzenesulfonamide (12): to a solution of 3-nitro-N-phenylbenzenesulfonamide (255.5 mg, 0.919 mmol) in tetrahydrofuran (THF, 4 mL) was added tin chloride dihydrate (SnCl2-2H2O, 1.015 g, 4.486 mmol). The reaction mixture was placed in a microwave reactor and was first heated at 135 °C for 1 min at a power of 75 Watt, then the power was adjusted to 15 Watt and the temperature was maintained at 135 °C for a further 14 min. Upon completion of the reaction, it was cooled to room temperature, diluted with ethyl acetate (EtOAc, 20 mL) and washed with saturated aqueous sodium bicarbonate (NaHCO3) (10 mL), followed by stirring for about 12 hours. The reaction mixture was extracted with ethyl acetate (75 mL), the organic layer was washed sequentially with water (75 mL), saturated sodium chloride (NaCl) aqueous solution (2 x 75 mL), dried with anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to give a yellow residue. The residue was purified by silica gel column chromatography (eluent: 0-4% gradient of methanol (MeOH) in dichloromethane (CH2Cl2)) to afford the target product 3-amino-N-phenylbenzenesulfonamide (178 mg, 78% yield). The product characterization data were as follows: 1H NMR (DMSO-d6, 300 MHz): δ 5.57 (s, 2H), 6.69 (d, J = 8.1 Hz, 1H), 6.84 (d, J = 7.5 Hz, 1H), 6.95 (s, 1H), 6.99 (t, J = 7.5 Hz, 1H), 7.07 (d, J = 8.1 Hz, 2H). 7.12 (t, J = 8.1 Hz, 1H), 7.21 (t, J = 8.1 Hz, 2H), 10.12 (s, 1H). Mass spectrum (ESI, cation mode) m/z: 249 ([M+H]+).
References
[1] Patent: US2007/293494, 2007, A1. Location in patent: Page/Page column 23; 24
[2] Archiv der Pharmazie, 2008, vol. 341, # 2, p. 99 - 112
[3] Journal of the American Chemical Society, 1946, vol. 68, p. 1039,1040, 1044
[4] Org. Synth. Coll. Vol., 1941, vol. I, p. 52
[5] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 10, p. 807
3-Aminobenzenesulfonanilide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3982 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3537 | 55 |
| Quzhou Juhua Friendship Co., Ltd | 0570-3066667 | China | 3922 | 58 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
View Latest Price from 3-Aminobenzenesulfonanilide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 3-Aminobenzenesulfonanilide
80-21-7
|
$1.00 | 1kg | 95%-99% | Career Henan Chemical Co |
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- 3-Aminobenzenesulfonanilide
80-21-7
- $1.00
- 95%-99%
- Career Henan Chemical Co
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