4-Nitrophenylacetic acid
- CAS No.
- 104-03-0
- Chemical Name:
- 4-Nitrophenylacetic acid
- Synonyms
- 2-(4-NITROPHENYL)ACETIC ACID;4-NITRO-A-TOLUIC ACID;4-NITROBENZENEACETIC ACID;paraNitro Phenyl Acetic Acid;4-Nitrophenylacetic;RARECHEM AL BO 0237;-Nitro-a-toluic acid;4-Nitrobenzencacetic;p-Nitro-α-toluicacid;Nitrophenylacetic aci
- CBNumber:
- CB1671726
- Molecular Formula:
- C8H7NO4
- Molecular Weight:
- 181.15
- MDL Number:
- MFCD00007383
- MOL File:
- 104-03-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Nitrophenylacetic acid ReagentPlus , 99% | N20204 | 25g | $59.4 |
| 4-Nitrophenylacetic acid ReagentPlus , 99% | N20204 | 100g | $105 |
| 4-Nitrophenylacetic Acid >98.0%(HPLC)(T) | N0227 | 25g | $34 |
| 4-Nitrophenylacetic Acid >98.0%(HPLC)(T) | N0227 | 500g | $254 |
| 4-Nitrophenylacetic Acid ≥98% | 433263 | 25g | $247 |
| More product size | |||
| Melting point | 150-155 °C(lit.) |
|---|---|
| Boiling point | 314.24°C (rough estimate) |
| Density | 1.4283 (rough estimate) |
| refractive index | 1.5468 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Crystalline Powder |
| pka | 3.85(at 25℃) |
| color | Beige to yellow |
| PH | 2.98 at 22.8℃ and 10g/L |
| Water Solubility | slightly soluble |
| Merck | 14,6621 |
| BRN | 1911801 |
| InChI | 1S/C8H7NO4/c10-8(11)5-6-1-3-7(4-2-6)9(12)13/h1-4H,5H2,(H,10,11) |
| InChIKey | YBADLXQNJCMBKR-UHFFFAOYSA-N |
| SMILES | OC(=O)Cc1ccc(cc1)[N+]([O-])=O |
| LogP | 0.3 at 30℃ and pH7.72 |
| CAS DataBase Reference | 104-03-0(CAS DataBase Reference) |
| FDA UNII | KLB4P626RE |
| EPA Substance Registry System | 4-Nitrophenylacetic acid (104-03-0) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318-H410 | |||||||||
| Precautionary statements | P273-P280-P305+P351+P338-P391-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AJ1130010 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29163900 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 |
|||||||||
| Toxicity | dnr-bcs 500 mg/disc MUREAV170,11,86 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4-Nitrophenylacetic acid price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N20204 | 4-Nitrophenylacetic acid ReagentPlus , 99% | 104-03-0 | 25g | $59.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | N20204 | 4-Nitrophenylacetic acid ReagentPlus , 99% | 104-03-0 | 100g | $105 | 2026-04-30 | Buy |
| TCI Chemical | N0227 | 4-Nitrophenylacetic Acid >98.0%(HPLC)(T) | 104-03-0 | 25g | $34 | 2026-04-30 | Buy |
| TCI Chemical | N0227 | 4-Nitrophenylacetic Acid >98.0%(HPLC)(T) | 104-03-0 | 500g | $254 | 2026-04-30 | Buy |
| Usbiological | 433263 | 4-Nitrophenylacetic Acid ≥98% | 104-03-0 | 25g | $247 | 2026-06-03 | Buy |
4-Nitrophenylacetic acid Chemical Properties,Uses,Production
Chemical Properties
Beige to yellow crystalline powder
4-Nitrophenylacetic acid is a member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the para- position by a nitro group.
Uses
Intermediate for dyestuffs, pharmaceuticals, penicillin precursors, local anesthetics.
Uses
(4-Nitrophenyl)acetic Acid used in the synthesis of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones which may act as angiogenesis inhibitors. Also used in the one step construction of amino-substituted squaraine dye.
Definition
ChEBI: A monocarboxylic acid that is phenylacetic acid carrying a nitro substituent at position 4.
Safety Profile
Moderately toxic intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Purification Methods
Crystallise the acid from EtOH/water (1:1), then from sodium-dried diethyl ether and dry it over P2O5 in vacuo. The styphnate has m 196.5-197o (prisms from EtOH). The amide has m 191o (from EtOH). [Beilstein 9 III 2284, 9 IV 1698.]
4-Nitrophenylacetic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Xinchem Co., Ltd. | +86-021-34123252 +8618049800532 | xinchem@xinchem.com | China | 49 | 58 |
| Beijing CosmicKoda Chemical Technology Co.,Ltd | 8615311061293 15311061293 | JeanWangCosmicKoda@outlook.com | China | 49 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
View Lastest Price from 4-Nitrophenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-05 | 4-Nitrophenylacetic acid
104-03-0
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-05-28 | 4-Nitrophenylacetic acid
104-03-0
|
$12.00 | 1KG | 99.% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | (4-nitrophenyl)acetic acid
104-03-0
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 4-Nitrophenylacetic acid
104-03-0
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- 4-Nitrophenylacetic acid
104-03-0
- $12.00
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- (4-nitrophenyl)acetic acid
104-03-0
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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