Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Amino-5-iodobenzonitrile

2-Amino-5-iodobenzonitrile

2-Amino-5-iodobenzonitrile Structure
2-Amino-5-iodobenzonitrile structure
CAS No.
132131-24-9
Chemical Name:
2-Amino-5-iodobenzonitrile
Synonyms
2-Cyano-4-iodoaniline;5-iodoanthranilonitrile;2-Amino-5-iodobenzonitrile;2-aminio-5-iodobenzonitrile;Benzonitrile, 2-amino-5-iodo-
CBNumber:
CB1672985
Molecular Formula:
C7H5IN2
Molecular Weight:
244.03
MDL Number:
MFCD07787432
MOL File:
132131-24-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:49:20
Request For Quotation

2-Amino-5-iodobenzonitrile Properties

Melting point 86℃ (ethanol )
Boiling point 333.6±37.0 °C(Predicted)
Density 1.98±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 1.02±0.10(Predicted)
Appearance Off-white to yellow Solid

2-Amino-5-iodobenzonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS24655 2-Amino-5-iodobenzonitrile 97% 132131-24-9 1g $56 2026-06-04 Buy
Activate Scientific AS24655 2-Amino-5-iodobenzonitrile 97% 132131-24-9 5g $166 2026-06-04 Buy
ACHEMBLOCK U139830 2-Amino-5-iodobenzonitrile 97% 132131-24-9 5G $115 2026-05-27 Buy
ACHEMBLOCK U139830 2-Amino-5-iodobenzonitrile 97% 132131-24-9 25G $405 2026-05-27 Buy
Crysdot CD12153878 2-Amino-5-iodobenzonitrile 97% 132131-24-9 1g $145 2026-05-27 Buy
Product number Packaging Price Buy
AS24655 1g $56 Buy
AS24655 5g $166 Buy
U139830 5G $115 Buy
U139830 25G $405 Buy
CD12153878 1g $145 Buy

2-Amino-5-iodobenzonitrile Chemical Properties, Uses, Production

Uses

2-Amino-5-iodobenzonitrile is a useful intermediate for the synthesis of lapatinib intermediate of N-[3-chloro-4-3-fluorophenzyloxyphenyl]-6-iodoquinazolin-4-amine.

Synthesis

2-Aminobenzonitrile

1885-29-6

2-AMINO-5-IODOBENZONITRILE

132131-24-9

The general procedure for the synthesis of 2-amino-5-iodobenzonitrile from 2-aminobenzonitrile is as follows: 1. A mixture of 2-aminobenzonitrile (0.02 mol) and ammonium iodide (0.02 mol) was dissolved in acetic acid (50 mL). 2. 30% aqueous hydrogen peroxide (0.13 mol) was added dropwise to the above solution slowly at 30 °C. 3. The reaction mixture was stirred at room temperature for 12 hours. 4. For 12 h. 4. After completion of the reaction, the reaction solution was treated with aqueous sodium thiosulfate (40 mL, 0.03 mol) and the pH was adjusted to about 8 by addition of 20% sodium hydroxide solution. 5. The reaction mixture was continued to be stirred at room temperature for 0.5 h. 6. The partially precipitated 2-amino-5- iodobenzonitrile (Product A) was separated by vacuum filtration to give a silvery-white flaky solid in a yield of 92.6%.

References

[1] Acta Crystallographica Section C: Crystal Structure Communications, 2007, vol. 63, # 7, p. o408-o410
[2] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 7, p. 1584 - 1587
[3] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 18, p. 4309 - 4313
[4] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 7, p. 2637 - 2649
[5] Patent: CN103896889, 2016, B. Location in patent: Paragraph 0041-0043

2-Amino-5-iodobenzonitrile Preparation Products And Raw materials

Raw materials

N-Iodosuccinimide 2-Aminobenzonitrile

Preparation Products

2-Amino-5-iodobenzonitrile Suppliers

Global Suppliers ( 89)
Supplier Tel Email Country ProdList Advantage
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9336 55
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5855 50
Supplier Advantage
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Adamas Reagent, Ltd. 59
Hunan Hui Bai Shi Biotechnology Co., Ltd. 62
Shanghai T&W Pharmaceutical Co., Ltd. 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Bide Pharmatech Ltd. 60
Nanjing Chalf-Pharm Technology Co., Ltd. 50

View Latest Price from 2-Amino-5-iodobenzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-AMINO-5-IODOBENZONITRILE pictures 2026-09-14 2-AMINO-5-IODOBENZONITRILE
132131-24-9
 0.99 RongNa Biotechnology Co.,Ltd
2-AMINO-5-IODOBENZONITRILE pictures 2026-07-08 2-AMINO-5-IODOBENZONITRILE
132131-24-9
 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
2-AMINO-5-IODOBENZONITRILE pictures 2019-07-06 2-AMINO-5-IODOBENZONITRILE
132131-24-9
 $1.00 1G 98% 100KG Career Henan Chemical Co

2-Amino-5-iodobenzonitrile Spectrum

2-AMINO-5-IODOBENZONITRILE(132131-24-9)1HNMR

132131-24-9 (2-Amino-5-iodobenzonitrile) Related Search:

2,3-Dichloro-6-fluorobenzonitrile 2-Amino-5-bromo-3-fluoro-benzonitrile 3,6-Dichloro-2-fluorobenzonitrile 2,4-Dihydroxybenzonitrile 2,4-difluoro-5-hydroxybenzonitrile
Benzonitrile, 2,5-difluoro-4-hydroxy- 2,5-Dibromo-3-fluorobenzonitrile 2-Amino-4,5-dichloro-benzonitrile Benzonitrile, 2-amino-3,6-difluoro- (9CI) 2,3-Dichloro-4-fluorobenzonitrile
3-BroMo-2,5-difluorobenzonitrile 2-aminobutanenitrile

1of3

2-Cyano-4-iodoaniline 2-aminio-5-iodobenzonitrile 5-iodoanthranilonitrile Benzonitrile, 2-amino-5-iodo- 2-Amino-5-iodobenzonitrile 132131-24-9 C7H5N2I