2,6-Dibromo-3-nitropyridine
- CAS No.
- 55304-80-8
- Chemical Name:
- 2,6-Dibromo-3-nitropyridine
- Synonyms
- 2,6-Dibromo-3-Nitropridine;2,6-DIBROMO-3-NITRO-PYRIDINE;2,6-dibromo-3-nitro-pryridine;Pyridine, 2,6-dibromo-3-nitro-;2,6-Dibromo-3-nitropyridine ,98%
- CBNumber:
- CB1673412
- Molecular Formula:
- C5H2Br2N2O2
- Molecular Weight:
- 281.89
- MDL Number:
- MFCD00233995
- MOL File:
- 55304-80-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,6-Dibromo-3-nitropyridine | D426045 | 5g | $85 |
| 2,6-Dibromo-3-nitropyridine 98.87% | CS-W000354 | 25g | $119 |
| 2,6-Dibromo-3-nitropyridine 98.87% | CS-W000354 | 100g | $223 |
| 2,6-Dibromo-3-nitropyridine | FD11914 | 50g | $260 |
| 2,6-Dibromo-3-nitropyridine | FD11914 | 100g | $440 |
| More product size | |||
| Melting point | 78 °C |
|---|---|
| Boiling point | 295.8±35.0 °C(Predicted) |
| Density | 2?+-.0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -7.68±0.10(Predicted) |
| color | Dark Yellow |
| InChI | InChI=1S/C5H2Br2N2O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H |
| InChIKey | FFRFTURYWWFKIC-UHFFFAOYSA-N |
| SMILES | C1(Br)=NC(Br)=CC=C1[N+]([O-])=O |
| CAS DataBase Reference | 55304-80-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| Hazard Codes | Xi |
| Safety Statements | 24/25 |
| HS Code | 29333990 |
2,6-Dibromo-3-nitropyridine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D426045 | 2,6-Dibromo-3-nitropyridine | 55304-80-8 | 5g | $85 | 2021-12-16 | Buy |
| ChemScene | CS-W000354 | 2,6-Dibromo-3-nitropyridine 98.87% | 55304-80-8 | 25g | $119 | 2021-12-16 | Buy |
| ChemScene | CS-W000354 | 2,6-Dibromo-3-nitropyridine 98.87% | 55304-80-8 | 100g | $223 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD11914 | 2,6-Dibromo-3-nitropyridine | 55304-80-8 | 50g | $260 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD11914 | 2,6-Dibromo-3-nitropyridine | 55304-80-8 | 100g | $440 | 2021-12-16 | Buy |
2,6-Dibromo-3-nitropyridine Chemical Properties,Uses,Production
Chemical Properties
Yellow powder
Uses
2,6-Dibromo-3-nitropyridine is a useful reagent for organic synthesis and other chemical processes. It is used as a reagent in the synthesis of amino(carbamoylmethyl) pyridones as factor VIIa inhibitors and anticoagulants.
Synthesis
16013-85-7
55304-80-8
The general procedure for the synthesis of 2,6-dibromo-3-nitropyridine from 2,6-dichloro-3-nitropyridine was as follows (Intermediate 6: 2,6-dibromo-3-nitropyridine, Scheme 12): Commercially available 2,6-dichloro-3-nitropyridine (10.0 g, 51.8 mmol) was mixed with a 33% HBr/AcOH solution (120 mL) and heated at 80°C. The reaction was carried out for 3 hours. The reaction was heated at 80°C for 3 hours. After completion of the reaction, the reaction solution was concentrated in vacuum. The resulting residue was dissolved in EtOAc and washed with saturated aqueous sodium bicarbonate. The organic phase was dried over anhydrous sodium sulfate and concentrated again under vacuum. The final product 2,6-dibromo-3-nitropyridine 14.4 g (99% yield) was obtained, which can be used as intermediate 6 without further purification. The product was analyzed by GC/MS showing a purity of 94% with a retention time (tR) of 7.56 min (tR of raw material was 6.93 min), and the characteristic peaks of the mass spectra (m/z) were 280/282/284 (M, 38%), 222/224/226 (35%), and 76 (100%), and the detection instrument was Finnegan LCQ.
References
[1] Patent: WO2006/24666, 2006, A1. Location in patent: Page/Page column 52
[2] Patent: WO2011/116176, 2011, A1. Location in patent: Page/Page column 70-71
[3] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 23, p. 6813 - 6817
[4] Patent: WO2005/75478, 2005, A1. Location in patent: Page/Page column 28
[5] Patent: EP1787991, 2007, A1. Location in patent: Page/Page column 36-37
2,6-Dibromo-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1087@dideu.com | China | 3977 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 2,6-Dibromo-3-nitropyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-01-03 | 2,6-Dibromo-3-nitropyridine
55304-80-8
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-02-25 | 2,6-Dibromo-3-nitropyridine
55304-80-8
|
US $5.00 / KG | 1KG | 99% | 10kg | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2022-02-25 | 2,6-Dibromo-3-nitropyridine
55304-80-8
|
US $5.00 / KG | 1KG | 98% | 100KG | Hong Kong Tiansheng New Material Trading Co., Ltd |
-
- 2,6-Dibromo-3-nitropyridine
55304-80-8
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2,6-Dibromo-3-nitropyridine
55304-80-8
- US $5.00 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- 2,6-Dibromo-3-nitropyridine
55304-80-8
- US $5.00 / KG
- 98%
- Hong Kong Tiansheng New Material Trading Co., Ltd
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