Atractylenolide III
- CAS No.
- 73030-71-4
- Chemical Name:
- Atractylenolide III
- Synonyms
- ATRACTYLENOLIDE;ICodonolactone;Leucolactone III;Atractylenolide-3;Atracylenolide III;8-HYDROXYASTEROLIDE;ATRACTYLENOLIDE III;Atractylenolide beta;Atractylodes lactone;Atractylenolide III, BR
- CBNumber:
- CB1678604
- Molecular Formula:
- C15H20O3
- Molecular Weight:
- 248.32
- MDL Number:
- MFCD00238543
- MOL File:
- 73030-71-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 166-169 °C(Solv: chloroform (67-66-3)) |
|---|---|
| Boiling point | 424.6±45.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | methanol: soluble1mg/mL, clear, colorless |
| pka | 10.73±0.60(Predicted) |
| form | powder or crystals |
| color | white to off-white |
| biological source | Atractylodes macrocephala Koidz. |
| Henry's Law Constant | 1.0×103 mol/(m3Pa) at 25℃, HSDB (2015) |
| Major Application |
metabolomics vitamins, nutraceuticals, and natural products |
| InChI | InChI=1S/C15H20O3/c1-9-5-4-6-14(3)8-15(17)12(7-11(9)14)10(2)13(16)18-15/h11,17H,1,4-8H2,2-3H3/t11-,14+,15-/m0/s1 |
| InChIKey | FBMORZZOJSDNRQ-GLQYFDAESA-N |
| SMILES | O1C(=O)C(C)=C2C[C@]3([H])[C@@](C)(C[C@]12O)CCCC3=C |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| WGK Germany | 3 |
|---|---|
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 73030-71-4(Hazardous Substances Data) |
Atractylenolide III price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A2987 | Atractylenolide III ≥98% (HPLC) | 73030-71-4 | 10mg | $415 | 2026-04-30 | Buy |
| Sigma-Aldrich | A2987 | Atractylenolide III ≥98% (HPLC) | 73030-71-4 | 50mg | $1250 | 2025-07-31 | Buy |
| TCI Chemical | A3609 | Atractylenolide III | 73030-71-4 | 100MG | $297 | 2026-04-30 | Buy |
| Cayman Chemical | 24911 | Atractylenolide III ≥98% | 73030-71-4 | 1mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 24911 | Atractylenolide III ≥98% | 73030-71-4 | 5mg | $242 | 2026-04-30 | Buy |
Atractylenolide III Chemical Properties, Uses, Production
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Atractylodes macrocephala Koidz.
Uses
Atractylenolide III enhances energy metabolism by increasing the SIRT-1 and PGC1α expression.
Definition
ChEBI: Atractylenolide III is a naphthofuran. It has a role as a metabolite.
Biological Activity
Atractylenolide III possesses anti-inflammatory and anticancer properties.
in vivo
Atractylenolide III (5 and 10 mg/kg, p.o.) shows gastroprotective effects and reduces 70% ethanol-induced gastric ulcer in rats[2].
Atractylenolide III (30 mg/kg, oral gavage for 14 days or 28 days) reduces depressive- and anxiogenic-like behaviors in rat depression models in Lipopolysaccharide (LPS) (HY-D1056) and chronic unpredictable mild stress (CUMS) induced rat depression model[5].
| Animal Model: | 70% ethanol-induced gastric ulcers in rats[2] |
| Dosage: | 5 and 10 mg/kg |
| Administration: | p.o. |
| Result: | Inhibited gastric ulcer formation and the necrotic erosion of gastric mucosa. Downregulated the MMP-2/9 expression by activating the TIMP-2 and TIMP-1 expressions. |
Atractylenolide III Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Moqi Biological Technology Co., LTD | 13341702378 | 190129269@qq.com | China | 9999 | 58 |
| Chengdu Biopurify Ltd. | 82633860 18982077548 | cwb1@biopurify.cn | China | 4630 | 58 |
| Nanjing Yuanzhi Biotechnology Co. Ltd. | 15805159960; | 1211550495@qq.com | China | 1797 | 58 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Shenzhen Sungening Bio-Tech Co., Ltd | +86-0755-89668383 | sales@sungening.com | China | 1319 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
View Latest Price from Atractylenolide III manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Atractylenolide III
73030-71-4
|
1g | 98% | 2000 | Changsha Staherb Natural Ingredients Co., Ltd. | ||
 |
2026-08-20 | Atractylenolide III
73030-71-4
|
$33.00-79.00 | 99.87% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | Atractylenolide III
73030-71-4
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Atractylenolide III
73030-71-4
- 98%
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Atractylenolide III
73030-71-4
- $33.00-79.00
- 99.87%
- TargetMol Chemicals Inc.
-
- Atractylenolide III
73030-71-4
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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