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Atractylenolide III

CAS No.
73030-71-4
Chemical Name:
Atractylenolide III
Synonyms
ICodonolactone;ATRACTYLENOLIDE;Leucolactone III;Atractylenolide-3;Atracylenolide III;8-HYDROXYASTEROLIDE;ATRACTYLENOLIDE III;Atractylenolide beta;Atractylenolide III, BR;Atractylenolide III USP/EP/BP
CBNumber:
CB1678604
Molecular Formula:
C15H20O3
Molecular Weight:
248.32
MDL Number:
MFCD00238543
MOL File:
73030-71-4.mol
MSDS File:
SDS
Last updated:2025-10-16 18:30:35
Product description Number Pack Size Price
Atractylenolide III ≥98% (HPLC) A2987 10mg $271.6
Atractylenolide III ≥98% (HPLC) A2987 50mg $1250
Atractylenolide III A3609 100MG $363
Atractylenolide III ≥98% 24911 1mg $57
Atractylenolide III ≥98% 24911 5mg $220
More product size

Atractylenolide III Properties

Melting point 166-169 °C(Solv: chloroform (67-66-3))
Boiling point 424.6±45.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility methanol: soluble1mg/mL, clear, colorless
pka 10.73±0.60(Predicted)
form powder or crystals
color white to off-white
biological source Atractylodes macrocephala Koidz.
InChI InChI=1S/C15H20O3/c1-9-5-4-6-14(3)8-15(17)12(7-11(9)14)10(2)13(16)18-15/h11,17H,1,4-8H2,2-3H3/t11-,14+,15-/m0/s1
InChIKey FBMORZZOJSDNRQ-GLQYFDAESA-N
SMILES O1C(=O)C(C)=C2C[C@]3([H])[C@@](C)(C[C@]12O)CCCC3=C
UNSPSC Code 41116107
NACRES NA.25

SAFETY

Risk and Safety Statements

WGK Germany  3
Hazardous Substances Data 73030-71-4(Hazardous Substances Data)

Atractylenolide III price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A2987 Atractylenolide III ≥98% (HPLC) 73030-71-4 10mg $271.6 2025-07-31 Buy
Sigma-Aldrich A2987 Atractylenolide III ≥98% (HPLC) 73030-71-4 50mg $1250 2025-07-31 Buy
TCI Chemical A3609 Atractylenolide III 73030-71-4 100MG $363 2025-07-31 Buy
Cayman Chemical 24911 Atractylenolide III ≥98% 73030-71-4 1mg $57 2024-03-01 Buy
Cayman Chemical 24911 Atractylenolide III ≥98% 73030-71-4 5mg $220 2024-03-01 Buy
Product number Packaging Price Buy
A2987 10mg $271.6 Buy
A2987 50mg $1250 Buy
A3609 100MG $363 Buy
24911 1mg $57 Buy
24911 5mg $220 Buy

Atractylenolide III Chemical Properties,Uses,Production

Uses

Atractylenolide III enhances energy metabolism by increasing the SIRT-1 and PGC1α expression.

Definition

ChEBI: Atractylenolide III is a naphthofuran. It has a role as a metabolite.

Biological Activity

Atractylenolide III possesses anti-inflammatory and anticancer properties.

in vivo

Atractylenolide III (5 and 10 mg/kg, p.o.) shows gastroprotective effects and reduces 70% ethanol-induced gastric ulcer in rats[2].
Atractylenolide III (30 mg/kg, oral gavage for 14 days or 28 days) reduces depressive- and anxiogenic-like behaviors in rat depression models in Lipopolysaccharide (LPS) (HY-D1056) and chronic unpredictable mild stress (CUMS) induced rat depression model[5].

Animal Model:70% ethanol-induced gastric ulcers in rats[2]
Dosage:5 and 10 mg/kg
Administration:p.o.
Result:Inhibited gastric ulcer formation and the necrotic erosion of gastric mucosa.
Downregulated the MMP-2/9 expression by activating the TIMP-2 and TIMP-1 expressions.

Atractylenolide III Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 271)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8772 58
Sichuan Zhuoyu Yantang Technology Co., Ltd.
+8613288715578 sales@sichuanzyyt.com China 12247 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 997 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58

View Lastest Price from Atractylenolide III manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Atractylenolide III pictures 2025-10-16 Atractylenolide III
73030-71-4
US $33.00-79.00 / mg 99.53% 10g TargetMol Chemicals Inc.
 Atractylenolide III pictures 2025-10-16 Atractylenolide III
73030-71-4
US $0.00-0.00 / g 1g 98% 2000 Changsha Staherb Natural Ingredients Co., Ltd.
Atractylenolide III pictures 2025-10-11 Atractylenolide III
73030-71-4
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
Atractylenolide III (ICodonolactone ICodonolactone ATRACTYLENOLIDE III 8-HYDROXYASTEROLIDE ATRACTYLENOLIDE Atractylenolide beta (4aS,8aR,9aS)-9a-Hydroxy-3,8a-dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzoxol-2-one (4aS)-4a,5,6,7,8,8a,9,9a-Octahydro-9aβ-hydroxy-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one Naphtho[2,3-b]furan-2(4H)-one,4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,8a-dimethyl-5-methylene-,(4aS,8aR,9aS)- Atractylenolide III000000, 98%, from Atractylodes macrocephala Koidz. Atractylenolide III, BR Atracylenolide III Atractylenolide III USP/EP/BP (4aS,8aR,9aS)-9a-Hydroxy-3,8a-dimethyl-5-methylene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one Atractylenolide-3 Leucolactone III Atractylenolide III, 10 mM in DMSO 73030-71-4 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Miscellaneous Natural Products