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Chymotrypsin Substrate II, Fluorogenic

CAS No.
88467-45-2
Chemical Name:
Chymotrypsin Substrate II, Fluorogenic
Synonyms
SUC-AAPF-AMC;FACTOR XIIA SUBSTRATE;Z-LYS-PHE-ARG-PNA 2HCL;SUC-ALA-ALA-PRO-PHE-MCA;SUC-ALA-ALA-PRO-PHE-AMC;Chymotrypsin Substrate II;Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE;Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC);FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE;CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC
CBNumber:
CB1701335
Molecular Formula:
C34H39N5O9
Molecular Weight:
661.7
MDL Number:
MFCD00080246
MOL File:
88467-45-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:07
Product description Number Pack Size Price
N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate S9761 1mg $104
Chymotrypsin Substrate II, Fluorogenic 230914 25mg $156
Chymotrypsin Substrate II, Fluorogenic ≥98% 41593 5mg $35
Chymotrypsin Substrate II, Fluorogenic ≥98% 41593 10mg $65
Chymotrypsin Substrate II, Fluorogenic ≥98% 41593 25mg $154

Chymotrypsin Substrate II, Fluorogenic Properties

Boiling point 1093.0±65.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Clear, colorless solution (10 mg/mL in Methanol)
form White lyophilized solid
pka 4.69±0.10(Predicted)
color White to off-white
Sequence {Suc}-Ala-Ala-Pro-Phe-{AMC}
InChIKey FMVUZZZUYBXQGR-UHFFFAOYSA-N
SMILES CC(NC(=O)CCC(O)=O)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(Cc2ccccc2)C(=O)Nc3ccc4C(C)=CC(=O)Oc4c3
UNSPSC Code 12352204
NACRES NA.77

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  3
Storage Class 11 - Combustible Solids

Chymotrypsin Substrate II, Fluorogenic price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S9761 N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate 88467-45-2 1mg $104 2026-04-30 Buy
Sigma-Aldrich 230914 Chymotrypsin Substrate II, Fluorogenic 88467-45-2 25mg $156 2026-04-30 Buy
Cayman Chemical 41593 Chymotrypsin Substrate II, Fluorogenic ≥98% 88467-45-2 5mg $35 2026-04-30 Buy
Cayman Chemical 41593 Chymotrypsin Substrate II, Fluorogenic ≥98% 88467-45-2 10mg $65 2026-04-30 Buy
Cayman Chemical 41593 Chymotrypsin Substrate II, Fluorogenic ≥98% 88467-45-2 25mg $154 2026-04-30 Buy
Product number Packaging Price Buy
S9761 1mg $104 Buy
230914 25mg $156 Buy
41593 5mg $35 Buy
41593 10mg $65 Buy
41593 25mg $154 Buy

Chymotrypsin Substrate II, Fluorogenic Chemical Properties,Uses,Production

Description

Chymotrypsin Substrate II, Fluorogenic finds widespread utility across diverse scientific research applications, encompassing the exploration of protein-protein interactions, enzyme kinetics, and receptor binding. Notably, its cost-effectiveness and user-friendly nature render it an appealing choice for researchers. Additionally, this peptide has been instrumental in delving into the intricate world of cell signaling pathways and unraveling the mechanisms governing gene expression regulation. It is postulated to function as a substrate for enzymes while also engaging with receptors. The prevailing belief suggests that the peptide effectively binds to specific receptors, subsequently triggering their activation and instigating consequential alterations in cellular signaling pathways.

Chemical Properties

White powder

Uses

Chymotrypsin Substrate II, Fluorogenic (cas# 88467-45-2) is a useful compound in organic synthesis and acts as a substrate for chymotrypsin enzyme.

Biological Activity

Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).

References

[1] G B IRVINE C H W M Ennis. Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay.[J]. Analytical biochemistry, 1990, 185 2: 304-307. DOI:10.1016/0003-2697(90)90298-n.
[2] LASZLO GRAF. Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin[J]. Biochemistry Biochemistry, 1987, 26 9: 2616-2623. DOI:10.1021/bi00383a031.
[3] OSHIMA G. Interaction of alpha-chymotrypsin with dimyristoyl phosphatidylcholine vesicles.[J]. Journal of biochemistry, 1984, 95 4: 1131-1136. DOI:10.1093/oxfordjournals.jbchem.a134701.
[4] OSHIMA G. Stimulation by phospholipid vesicles of proteolysis of egg white lysozyme by chymotrypsin.[J]. Journal of biochemistry, 1983, 5 1: 1615-1620. DOI:10.1093/OXFORDJOURNALS.JBCHEM.A134509.

Chymotrypsin Substrate II, Fluorogenic Preparation Products And Raw materials

Raw materials

Preparation Products

Chymotrypsin Substrate II, Fluorogenic Suppliers

Global( 73)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30224 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9333 58
Nanjing TGpeptide
+86-13347807150 support@tgpeptide.com China 3279 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599 info@molchanges.com China 5218 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
LEON (NANJING) BIOTECHNOLOGY CO., LTD.
+8615051830413 sales.njleonbiotech@gmail.com China 5482 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15838 69
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64

View Lastest Price from Chymotrypsin Substrate II, Fluorogenic manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE pictures 2025-04-04 FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE
88467-45-2
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE 4-METHYLCOUMARYL-7-AMIDE SUC-AAPF-AMC SUC-ALA-ALA-PRO-PHE-MCA SUC-ALA-ALA-PRO-PHE-7-AMINO-4-METHYLCOUMARIN SUC-ALA-ALA-PRO-PHE-AMC N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-METHYLCOUMARIN Z-LYS-PHE-ARG-PNA 2HCL Chymotrypsin Substrate II, Fluorogenic - CAS 88467-45-2 - Calbiochem CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-*ME THYLCOUMARI FACTOR XIIA SUBSTRATE succinylalanylalanyl-prolyl-phenylalanine-4-methylcoumaryl-7-amide Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC) L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- 5:PN:WO0197794 SEQID:34 claimed protein 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-2-[(4-methyl-2-oxochromen-7-yl)amino]-3-phenylpropanoyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Phenylalaninamide Chymotrypsin Substrate II 88467-45-2 C34H39N5O9 Enzymes, Inhibitors, and Substrates Enzyme Substrates Leucine Aminopeptidase Substrates by Enzyme BioChemical Biochemicals and Reagents Chymotrypsin, alphaEnzyme Substrates Leucine aminopeptidase Leucine AminopeptidaseEnzyme Substrates Enzyme Substrates Protease Substrates Substrates by Enzyme