Chymotrypsin Substrate II, Fluorogenic
- CAS No.
- 88467-45-2
- Chemical Name:
- Chymotrypsin Substrate II, Fluorogenic
- Synonyms
- SUC-AAPF-AMC;FACTOR XIIA SUBSTRATE;Z-LYS-PHE-ARG-PNA 2HCL;SUC-ALA-ALA-PRO-PHE-MCA;SUC-ALA-ALA-PRO-PHE-AMC;Chymotrypsin Substrate II;Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE;Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC);FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE;CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC
- CBNumber:
- CB1701335
- Molecular Formula:
- C34H39N5O9
- Molecular Weight:
- 661.7
- MDL Number:
- MFCD00080246
- MOL File:
- 88467-45-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate | S9761 | 1mg | $104 |
| Chymotrypsin Substrate II, Fluorogenic | 230914 | 25mg | $156 |
| Chymotrypsin Substrate II, Fluorogenic ≥98% | 41593 | 5mg | $35 |
| Chymotrypsin Substrate II, Fluorogenic ≥98% | 41593 | 10mg | $65 |
| Chymotrypsin Substrate II, Fluorogenic ≥98% | 41593 | 25mg | $154 |
| Boiling point | 1093.0±65.0 °C(Predicted) |
|---|---|
| Density | 1.347±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Clear, colorless solution (10 mg/mL in Methanol) |
| form | White lyophilized solid |
| pka | 4.69±0.10(Predicted) |
| color | White to off-white |
| Sequence | {Suc}-Ala-Ala-Pro-Phe-{AMC} |
| InChIKey | FMVUZZZUYBXQGR-UHFFFAOYSA-N |
| SMILES | CC(NC(=O)CCC(O)=O)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(Cc2ccccc2)C(=O)Nc3ccc4C(C)=CC(=O)Oc4c3 |
| UNSPSC Code | 12352204 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
Chymotrypsin Substrate II, Fluorogenic price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S9761 | N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate | 88467-45-2 | 1mg | $104 | 2026-04-30 | Buy |
| Sigma-Aldrich | 230914 | Chymotrypsin Substrate II, Fluorogenic | 88467-45-2 | 25mg | $156 | 2026-04-30 | Buy |
| Cayman Chemical | 41593 | Chymotrypsin Substrate II, Fluorogenic ≥98% | 88467-45-2 | 5mg | $35 | 2026-04-30 | Buy |
| Cayman Chemical | 41593 | Chymotrypsin Substrate II, Fluorogenic ≥98% | 88467-45-2 | 10mg | $65 | 2026-04-30 | Buy |
| Cayman Chemical | 41593 | Chymotrypsin Substrate II, Fluorogenic ≥98% | 88467-45-2 | 25mg | $154 | 2026-04-30 | Buy |
Chymotrypsin Substrate II, Fluorogenic Chemical Properties,Uses,Production
Description
Chymotrypsin Substrate II, Fluorogenic finds widespread utility across diverse scientific research applications, encompassing the exploration of protein-protein interactions, enzyme kinetics, and receptor binding. Notably, its cost-effectiveness and user-friendly nature render it an appealing choice for researchers. Additionally, this peptide has been instrumental in delving into the intricate world of cell signaling pathways and unraveling the mechanisms governing gene expression regulation. It is postulated to function as a substrate for enzymes while also engaging with receptors. The prevailing belief suggests that the peptide effectively binds to specific receptors, subsequently triggering their activation and instigating consequential alterations in cellular signaling pathways.
Chemical Properties
White powder
Uses
Chymotrypsin Substrate II, Fluorogenic (cas# 88467-45-2) is a useful compound in organic synthesis and acts as a substrate for chymotrypsin enzyme.
Biological Activity
Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).
References
[1] G B IRVINE C H W M Ennis. Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay.[J]. Analytical biochemistry, 1990, 185 2: 304-307. DOI:10.1016/0003-2697(90)90298-n.
[2] LASZLO GRAF. Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin[J]. Biochemistry Biochemistry, 1987, 26 9: 2616-2623. DOI:10.1021/bi00383a031.
[3] OSHIMA G. Interaction of alpha-chymotrypsin with dimyristoyl phosphatidylcholine vesicles.[J]. Journal of biochemistry, 1984, 95 4: 1131-1136. DOI:10.1093/oxfordjournals.jbchem.a134701.
[4] OSHIMA G. Stimulation by phospholipid vesicles of proteolysis of egg white lysozyme by chymotrypsin.[J]. Journal of biochemistry, 1983, 5 1: 1615-1620. DOI:10.1093/OXFORDJOURNALS.JBCHEM.A134509.
Chymotrypsin Substrate II, Fluorogenic Preparation Products And Raw materials
Raw materials
Preparation Products
Chymotrypsin Substrate II, Fluorogenic Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9333 | 58 |
| Nanjing TGpeptide | +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5218 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| LEON (NANJING) BIOTECHNOLOGY CO., LTD. | +8615051830413 | sales.njleonbiotech@gmail.com | China | 5482 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
View Lastest Price from Chymotrypsin Substrate II, Fluorogenic manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE
88467-45-2
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-

- FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE
88467-45-2
- 98%
- Henan Aochuang Chemical Co.,Ltd.
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