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Chymotrypsin Substrate II, Fluorogenic

Chymotrypsin Substrate II, Fluorogenic structure

CAS No.: 88467-45-2

Chemical Name:: Chymotrypsin Substrate II, Fluorogenic

Synonyms: SUC-AAPF-AMC;FACTOR XIIA SUBSTRATE;Z-LYS-PHE-ARG-PNA 2HCL;SUC-ALA-ALA-PRO-PHE-MCA;SUC-ALA-ALA-PRO-PHE-AMC;Chymotrypsin Substrate II;Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE;Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC);FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE;CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC

CBNumber:: CB1701335

Molecular Formula:: C34H39N5O9

Molecular Weight:: 661.7

MDL Number:: MFCD00080246

MOL File:: 88467-45-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:59:07

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Chymotrypsin Substrate II, Fluorogenic Properties

Boiling point	1093.0±65.0 °C(Predicted)
Density	1.347±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Clear, colorless solution (10 mg/mL in Methanol)
form	White lyophilized solid
pka	4.69±0.10(Predicted)
color	White to off-white
Sequence	{Suc}-Ala-Ala-Pro-Phe-{AMC}
InChIKey	FMVUZZZUYBXQGR-UHFFFAOYSA-N
SMILES	CC(NC(=O)CCC(O)=O)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(Cc2ccccc2)C(=O)Nc3ccc4C(C)=CC(=O)Oc4c3
UNSPSC Code	12352204
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	11 - Combustible Solids

Chymotrypsin Substrate II, Fluorogenic price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S9761	N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate	88467-45-2	1mg	$104	2026-04-30	Buy
Sigma-Aldrich	230914	Chymotrypsin Substrate II, Fluorogenic	88467-45-2	25mg	$156	2026-04-30	Buy
Cayman Chemical	41593	Chymotrypsin Substrate II, Fluorogenic ≥98%	88467-45-2	5mg	$35	2026-04-30	Buy
Cayman Chemical	41593	Chymotrypsin Substrate II, Fluorogenic ≥98%	88467-45-2	10mg	$65	2026-04-30	Buy
Cayman Chemical	41593	Chymotrypsin Substrate II, Fluorogenic ≥98%	88467-45-2	25mg	$154	2026-04-30	Buy

Product number	Packaging	Price	Buy
S9761	1mg	$104	Buy
230914	25mg	$156	Buy
41593	5mg	$35	Buy
41593	10mg	$65	Buy
41593	25mg	$154	Buy

Chymotrypsin Substrate II, Fluorogenic Chemical Properties,Uses,Production

Description

Chymotrypsin Substrate II, Fluorogenic finds widespread utility across diverse scientific research applications, encompassing the exploration of protein-protein interactions, enzyme kinetics, and receptor binding. Notably, its cost-effectiveness and user-friendly nature render it an appealing choice for researchers. Additionally, this peptide has been instrumental in delving into the intricate world of cell signaling pathways and unraveling the mechanisms governing gene expression regulation. It is postulated to function as a substrate for enzymes while also engaging with receptors. The prevailing belief suggests that the peptide effectively binds to specific receptors, subsequently triggering their activation and instigating consequential alterations in cellular signaling pathways.

Chemical Properties

White powder

Uses

Chymotrypsin Substrate II, Fluorogenic (cas# 88467-45-2) is a useful compound in organic synthesis and acts as a substrate for chymotrypsin enzyme.

Biological Activity

Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).

References

[1] G B IRVINE C H W M Ennis. Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay.[J]. Analytical biochemistry, 1990, 185 2: 304-307. DOI:10.1016/0003-2697(90)90298-n.
[2] LASZLO GRAF. Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin[J]. Biochemistry Biochemistry, 1987, 26 9: 2616-2623. DOI:10.1021/bi00383a031.
[3] OSHIMA G. Interaction of alpha-chymotrypsin with dimyristoyl phosphatidylcholine vesicles.[J]. Journal of biochemistry, 1984, 95 4: 1131-1136. DOI:10.1093/oxfordjournals.jbchem.a134701.
[4] OSHIMA G. Stimulation by phospholipid vesicles of proteolysis of egg white lysozyme by chymotrypsin.[J]. Journal of biochemistry, 1983, 5 1: 1615-1620. DOI:10.1093/OXFORDJOURNALS.JBCHEM.A134509.

Chymotrypsin Substrate II, Fluorogenic Preparation Products And Raw materials

Raw materials

Preparation Products

Chymotrypsin Substrate II, Fluorogenic Suppliers

Global( 73)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Nanjing Dulai Biotechnology Co., Ltd.	025-84699383-8003;025-846993838003-8003 18013301590	njduly@126.com	China	3293	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51389	80
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Nanjing Leon Biological Technology Co., Ltd.	025-84523390 -127; 17705183659	sales@njleonbiotech.com	China	5501	55
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919 15967184799	Eric@peptidego.com	China	7872	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Nanjing Dulai Biotechnology Co., Ltd.	55
Sigma-Aldrich	80
Shanghai YuanYe Biotechnology Co., Ltd.	60
Nanjing Leon Biological Technology Co., Ltd.	55
Nanjing Peptide Biotech Ltd.	55
Hangzhou Peptidego Biotech Co.,Ltd.	58

View Lastest Price from Chymotrypsin Substrate II, Fluorogenic manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-04-04	FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE 88467-45-2		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE
88467-45-2
98%
Henan Aochuang Chemical Co.,Ltd.

88467-45-2(Chymotrypsin Substrate II, Fluorogenic)Related Search:

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SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE 4-METHYLCOUMARYL-7-AMIDE SUC-AAPF-AMC SUC-ALA-ALA-PRO-PHE-MCA SUC-ALA-ALA-PRO-PHE-7-AMINO-4-METHYLCOUMARIN SUC-ALA-ALA-PRO-PHE-AMC N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-METHYLCOUMARIN Z-LYS-PHE-ARG-PNA 2HCL Chymotrypsin Substrate II, Fluorogenic - CAS 88467-45-2 - Calbiochem CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-*ME THYLCOUMARI FACTOR XIIA SUBSTRATE succinylalanylalanyl-prolyl-phenylalanine-4-methylcoumaryl-7-amide Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC) L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- 5:PN:WO0197794 SEQID:34 claimed protein 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-2-[(4-methyl-2-oxochromen-7-yl)amino]-3-phenylpropanoyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Phenylalaninamide Chymotrypsin Substrate II 88467-45-2 C34H39N5O9 Enzymes, Inhibitors, and Substrates Enzyme Substrates Leucine Aminopeptidase Substrates by Enzyme BioChemical Biochemicals and Reagents Chymotrypsin, alphaEnzyme Substrates Leucine aminopeptidase Leucine AminopeptidaseEnzyme Substrates Enzyme Substrates Protease Substrates Substrates by Enzyme