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TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE structure

CAS No.: 903129-71-5

Chemical Name:: TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE

Synonyms: 6-Boc-2,4-dichloro-6,7-di...;tert-butyl 2,4-dichloro-5H-pyrrolo[3,4-;6-Boc-2,4-Dichloro-5,7-dihydropyrrolo[3,4-d]pyriMidine;2,4-Dichloro-6,7-dihydro-6-Boc-5H-pyrrolo[3,4-d]pyrimidine;6-Boc-2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyriMidine;tert-butyl 2,4-dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimid...;tert-Butyl 2,4-dichloro-5H-pyrrolo[3,4-d]pyriMidine-6(7H)-carbox;ert-Butyl2,4-dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate;TERT-BUTYL 2,4-DICHLORO-5H,7H-PYRROLO[3,4-D]PYRIMIDINE-6-CARBOXYLATE;TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE

CBNumber:: CB1719253

Molecular Formula:: C11H13Cl2N3O2

Molecular Weight:: 290.15

MDL Number:: MFCD08273919

MOL File:: 903129-71-5.mol

Last updated:2025-07-24 18:13:52

Request For Quotation

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE Properties

Boiling point	405.8±45.0 °C(Predicted)
Density	1.400±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	-2.24±0.20(Predicted)
Appearance	White to off-white Solid
InChI	InChI=1S/C11H13Cl2N3O2/c1-11(2,3)18-10(17)16-4-6-7(5-16)14-9(13)15-8(6)12/h4-5H2,1-3H3
InChIKey	WUYSMOCOXBLFKK-UHFFFAOYSA-N
SMILES	C1(Cl)=NC(Cl)=C2CN(C(OC(C)(C)C)=O)CC2=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H317-H319
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B695325	tert-Butyl2,4-Dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate	903129-71-5	50mg	$45	2021-12-16	Buy
Matrix Scientific	069980	tert-Butyl 2,4-Dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate >95%	903129-71-5	500mg	$94	2021-12-16	Buy
Matrix Scientific	069980	tert-Butyl 2,4-Dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate >95%	903129-71-5	1g	$145	2021-12-16	Buy
SynQuest Laboratories	4H56-1-008	6-Boc-2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine	903129-71-5	1g	$175	2021-12-16	Buy
Biosynth Carbosynth	FB143128	tert-Butyl 2,4-dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate	903129-71-5	1g	$220	2021-12-16	Buy

Product number	Packaging	Price	Buy
B695325	50mg	$45	Buy
069980	500mg	$94	Buy
069980	1g	$145	Buy
4H56-1-008	1g	$175	Buy
FB143128	1g	$220	Buy

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE Chemical Properties,Uses,Production

Uses

tert-butyl 2,4-dichloro-5H,6H,7H-pyrrolo[3,4-d]pyrimidine-6-carboxylate is used as an intermediate in organic synthesis.

Synthesis

2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyriMidine

785775-01-1

24424-99-5

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE

903129-71-5

General procedure for the synthesis of 6-Boc-2,4-dichloro-5,7-dihydropyrrolo[3,4-d]pyrimidines from 2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidines and di-tert-butyl dicarbonate: 17.67 g of di-tert-butyl dicarbonate was dissolved in dichloromethane and cooled down to 0 °C, then slowly added dropwise 2,4-dichloro-6,7-dihydro-5H -pyrrolo[3,4-d]pyrimidine (exact mass not provided) followed by the addition of 23.417 mL of triethylamine. The reaction mixture was stirred at room temperature for 3 hours. The progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was washed three times with water and the organic phase was dried with anhydrous sodium sulfate. Finally, purification by column chromatography using dichloromethane: methanol = 20:1 (v/v) as mobile phase gave 4.12 g of the light yellow solid product 6-Boc-2,4-dichloro-5,7-dihydropyrrolo[3,4-d]pyrimidine in 23% yield.

References

[1] Patent: CN102584828, 2016, B. Location in patent: Paragraph 0114-0116

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE Preparation Products And Raw materials

Raw materials

2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyriMidine Di-tert-butyl dicarbonate Dichloromethane Triethylamine

Preparation Products

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE Suppliers

Global( 166)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	1382	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29800	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
ATK CHEMICAL COMPANY LIMITED	60
Accela ChemBio Inc.	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Career Henan Chemica Co	58

View Lastest Price from TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-03-08	TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE 903129-71-5	US $3.00 / KG	1KG	99%min	500kg	Career Henan Chemical Co

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE
903129-71-5
US $3.00 / KG
99%min
Career Henan Chemical Co

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE Spectrum

TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE(903129-71-5)¹HNMR

903129-71-5(TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE)Related Search:

6-broMopyrrolo[1,2-f][1,2,4]triazin-4(3H)-one 4-AMino-6-broMopyrrolo[1,2-f][1,2,4]triazine 6-BROMO-4-CHLOROPYRROLO[1,2-F][1,2,4]TRIAZINE tert-butyl 3-iodo-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate 3-benzyl-7-oxa-3-aza-bicyclo[4.1.0]heptane

TERT-BUTYL 2,4-DICHLORO-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDINE-6(5H)-CARBOXYLATE tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate tert-butyl 4-amino-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate 2-Phenyl-5,7-dihydro-pyrrolo[3,4-d]pyriMidine -6-carboxylic acid tert-butyl ester tert-butyl 2-(trifluoroMethyl)-5,6-dihydropyrido[3,4-d]pyriMidine-7(8H)-carboxylate

tert-butyl 4-hydroxy-2-methyl-5H,6H,7H-pyrrolo[3,4-d]pyrimidine-6-carboxylate TERT-BUTYL 4-AMINO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE 2-Methyl-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester 5H-Pyrrolo[3,4-d]pyrimidine, 6,7-dihydro- (9CI) 2,4-Dichloro-5-methylpyrimidine

2,4-Dichloro-6-methylpyrimidine TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE 6,7-DIHYDRO-5H-PYRROLO-[3,4-D]-PYRIMIDINE DIHYDROCHLORIDE

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TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE 2,4-Dichloro-6,7-dihydro-6-Boc-5H-pyrrolo[3,4-d]pyrimidine tert-butyl 2,4-dichloro-5H-pyrrolo[3,4- 6H-Pyrrolo[3,4-d]pyrimidine-6-carboxylicacid, 2,4-dichloro-5,7-dihydro-, 1,1-dimethylethyl ester tert-Butyl 2,4-dichloro-5H-pyrrolo[3,4-d]pyriMidine-6(7H)-carbox 6-Boc-2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyriMidine 6-Boc-2,4-dichloro-6,7-di... 2,4-Dichloro-5,7-dihydro-pyrrolo[3,4-d]pyriMidine-6-carboxylic acid tert-butyl ester 2,4-Dichloro-5,7-dihydro-6h-pyrrolo[3,4-d]pyriMidine-6-carboxylic acid 1,1-diMethylethyl ester tert-butyl 2,4-dichloro-5H,6H,7H-pyrrolo[3,4-d]pyriMidine-6-carboxylate 6-Boc-2,4-Dichloro-5,7-dihydropyrrolo[3,4-d]pyriMidine tert-Butyl 2,4-dichloro-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate TERT-BUTYL 2,4-DICHLORO-5H,7H-PYRROLO[3,4-D]PYRIMIDINE-6-CARBOXYLATE ert-Butyl2,4-dichloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylate tert-butyl 2,4-dichloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimid... 903129-71-5 Heterocycle-Pyrimidine series CHIRAL CHEMICALS