4-Methylbenzyl chloride
- CAS No.
- 104-82-5
- Chemical Name:
- 4-Methylbenzyl chloride
- Synonyms
- 1-(Chloromethyl)-4-methylbenzene;MBC;P-XYLYL CHLORIDE;P-METHYLBENZYL CHLORIDE;PXCL1;pha-ChL;oro-p-xyL;4-Xylyl chloride;A-CHLORO-P-XYLENE;AKOS BBS-00003956
- CBNumber:
- CB1735857
- Molecular Formula:
- C8H9Cl
- Molecular Weight:
- 140.61
- MDL Number:
- MFCD00000919
- MOL File:
- 104-82-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Methylbenzyl chloride 98% | C73400 | 5g | $50.3 |
| 4-Methylbenzyl chloride 98% | C73400 | 100g | $86.6 |
| α-Chloro-p-xylene | C0312 | 25G | $27 |
| α-Chloro-p-xylene | C0312 | 500G | $102 |
| α-Chloro-p-methyltoluene | C369770 | 25g | $150 |
| More product size | |||
| Melting point | 4 °C(lit.) |
|---|---|
| Boiling point | 200 °C(lit.) |
| Density | 1.062 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 168 °F |
| storage temp. | 2-8°C |
| form | Low Melting Solid or Liquid |
| color | Colorless to white to yellow |
| Water Solubility | Insoluble |
| Sensitive | Lachrymatory |
| Merck | 14,10091 |
| BRN | 507387 |
| InChI | 1S/C8H9Cl/c1-7-2-4-8(6-9)5-3-7/h2-5H,6H2,1H3 |
| InChIKey | DMHZDOTYAVHSEH-UHFFFAOYSA-N |
| SMILES | Cc1ccc(CCl)cc1 |
| CAS DataBase Reference | 104-82-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 858830J11H |
| NIST Chemistry Reference | Benzene, 1-(chloromethyl)-4-methyl-(104-82-5) |
| EPA Substance Registry System | Benzene, 1-(chloromethyl)-4-methyl- (104-82-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 34-36/37/38-22 | |||||||||
| Safety Statements | 26-27-36/37/39-45-37/39 | |||||||||
| RIDADR | UN 2922 8/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | ZE4030000 | |||||||||
| F | 19 | |||||||||
| Hazard Note | Harmful/Corrosive/Lachrymatory | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29036990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Corr. 1B |
|||||||||
| Hazardous Substances Data | 104-82-5(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
4-Methylbenzyl chloride price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C73400 | 4-Methylbenzyl chloride 98% | 104-82-5 | 5g | $50.3 | 2026-03-19 | Buy |
| Sigma-Aldrich | C73400 | 4-Methylbenzyl chloride 98% | 104-82-5 | 100g | $86.6 | 2026-03-19 | Buy |
| TCI Chemical | C0312 | α-Chloro-p-xylene | 104-82-5 | 25G | $27 | 2026-03-19 | Buy |
| TCI Chemical | C0312 | α-Chloro-p-xylene | 104-82-5 | 500G | $102 | 2026-03-19 | Buy |
| TRC | C369770 | α-Chloro-p-methyltoluene | 104-82-5 | 25g | $150 | 2021-12-16 | Buy |
4-Methylbenzyl chloride Chemical Properties,Uses,Production
Chemical Properties
clear colourless to light yellow liquid
Uses
α-Chloro-p-methyltoluene-13C is the labeled analogue of α-Chloro-p-methyltoluene(C369770). α-Chloro-p-methyltoluene is a building block that has been used as a reactant for the preparation of 6-aminoquinolone derivatives as submicromolar hepatitis C virus NS5B inhibitors
Synthesis
The main process for the industrial production of 4-methylbenzyl chloride is currently based on 3-hydroxybenzaldehyde as raw material, and the target product is obtained by methylation with dimethyl sulfate, reduction with potassium borohydride or hydrogenation, and chlorination with alum chloride or concentrated hydrochloric acid.
Purification Methods
Dry the chloride with CaSO4 and fractionally distil it under vacuum. [Beilstein 5 H 384, 5 III 854, 5 IV 966.]
4-Methylbenzyl chloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taixing Foreign Trade Nanjing Co., Ltd. | +86-025-83346564; +8613182976929 | sales@tx-chem.com | China | 125 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +8617392709771 | 1097@dideu.com | China | 3996 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21591 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
View Lastest Price from 4-Methylbenzyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 4-Methylbenzyl chloride
104-82-5
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-12-24 | 4-Methylbenzyl chloride
104-82-5
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | |
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2025-12-01 | 4-Methylbenzyl chloride
104-82-5
|
US $0.00-0.00 / KG | 1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-

- 4-Methylbenzyl chloride
104-82-5
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 4-Methylbenzyl chloride
104-82-5
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-

- 4-Methylbenzyl chloride
104-82-5
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
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