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4-Methylbenzyl chloride

CAS No.
104-82-5
Chemical Name:
4-Methylbenzyl chloride
Synonyms
1-(Chloromethyl)-4-methylbenzene;MBC;P-XYLYL CHLORIDE;P-METHYLBENZYL CHLORIDE;PXCL1;pha-ChL;oro-p-xyL;4-Xylyl chloride;A-CHLORO-P-XYLENE;AKOS BBS-00003956
CBNumber:
CB1735857
Molecular Formula:
C8H9Cl
Molecular Weight:
140.61
MDL Number:
MFCD00000919
MOL File:
104-82-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:57
Product description Number Pack Size Price
4-Methylbenzyl chloride 98% C73400 5g $50.3
4-Methylbenzyl chloride 98% C73400 100g $86.6
α-Chloro-p-xylene C0312 25G $27
α-Chloro-p-xylene C0312 500G $102
α-Chloro-p-methyltoluene C369770 25g $150
More product size

4-Methylbenzyl chloride Properties

Melting point 4 °C(lit.)
Boiling point 200 °C(lit.)
Density 1.062 g/mL at 25 °C(lit.)
refractive index n20/D 1.533(lit.)
Flash point 168 °F
storage temp. 2-8°C
form Low Melting Solid or Liquid
color Colorless to white to yellow
Water Solubility Insoluble
Sensitive Lachrymatory
Merck 14,10091
BRN 507387
InChI 1S/C8H9Cl/c1-7-2-4-8(6-9)5-3-7/h2-5H,6H2,1H3
InChIKey DMHZDOTYAVHSEH-UHFFFAOYSA-N
SMILES Cc1ccc(CCl)cc1
CAS DataBase Reference 104-82-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 858830J11H
NIST Chemistry Reference Benzene, 1-(chloromethyl)-4-methyl-(104-82-5)
EPA Substance Registry System Benzene, 1-(chloromethyl)-4-methyl- (104-82-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C,Xi
Risk Statements  34-36/37/38-22
Safety Statements  26-27-36/37/39-45-37/39
RIDADR  UN 2922 8/PG 3
WGK Germany  1
RTECS  ZE4030000
19
Hazard Note  Harmful/Corrosive/Lachrymatory
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29036990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Skin Corr. 1B
Hazardous Substances Data 104-82-5(Hazardous Substances Data)
NFPA 704
2
3 0

4-Methylbenzyl chloride price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C73400 4-Methylbenzyl chloride 98% 104-82-5 5g $50.3 2026-03-19 Buy
Sigma-Aldrich C73400 4-Methylbenzyl chloride 98% 104-82-5 100g $86.6 2026-03-19 Buy
TCI Chemical C0312 α-Chloro-p-xylene 104-82-5 25G $27 2026-03-19 Buy
TCI Chemical C0312 α-Chloro-p-xylene 104-82-5 500G $102 2026-03-19 Buy
TRC C369770 α-Chloro-p-methyltoluene 104-82-5 25g $150 2021-12-16 Buy
Product number Packaging Price Buy
C73400 5g $50.3 Buy
C73400 100g $86.6 Buy
C0312 25G $27 Buy
C0312 500G $102 Buy
C369770 25g $150 Buy

4-Methylbenzyl chloride Chemical Properties,Uses,Production

Chemical Properties

clear colourless to light yellow liquid

Uses

α-Chloro-p-methyltoluene-13C is the labeled analogue of α-Chloro-p-methyltoluene(C369770). α-Chloro-p-methyltoluene is a building block that has been used as a reactant for the preparation of 6-aminoquinolone derivatives as submicromolar hepatitis C virus NS5B inhibitors

Synthesis

The main process for the industrial production of 4-methylbenzyl chloride is currently based on 3-hydroxybenzaldehyde as raw material, and the target product is obtained by methylation with dimethyl sulfate, reduction with potassium borohydride or hydrogenation, and chlorination with alum chloride or concentrated hydrochloric acid.

Purification Methods

Dry the chloride with CaSO4 and fractionally distil it under vacuum. [Beilstein 5 H 384, 5 III 854, 5 IV 966.]

Global( 474)Suppliers
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Taixing Foreign Trade Nanjing Co., Ltd.
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View Lastest Price from 4-Methylbenzyl chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methylbenzyl chloride pictures 2026-03-20 4-Methylbenzyl chloride
104-82-5
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
4-Methylbenzyl chloride pictures 2025-12-24 4-Methylbenzyl chloride
104-82-5
US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
4-Methylbenzyl chloride pictures 2025-12-01 4-Methylbenzyl chloride
104-82-5
US $0.00-0.00 / KG 1KG 99.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
MBC METHYLBENZYLCHLORIDE(4-) 4-METHYLBENZYL CHLORIDE A-CHLORO-P-XYLENE ALPHA-CHLORO-4-XYLENE ALPHA-CHLORO-P-XYLENE AKOS BBS-00003956 P-XYLYL CHLORIDE PXCL1 P-METHYLBENZYL CHLORIDE (4-methylphenyl)methylchloride (Chloromethyl)toluene (2-(chloromethyl) plus 4-(chloromethyl)) (p-chloromethyl)toluene 1-(chloromethyl)-4-methyl-benzen 4-Xylyl chloride alpha-Chloro-p-xylene, 99+% à-chloro-p-xylene 4-Methylbenzyl chloride 99% PARA-METHYLBENZYLCHLORIDE 4-Methyl-1-chlormethylbenzol 6) PARA METHYL BENZYL CHLORIDE ALPHA-CHLORO-P-XYLENE (4-METHYLBENZYL CHLORIDE) alpha-Chloro-p-xylene, p-Xylyl chloride α-Chloro-p-xylene, p-Xylyl chloride 4-Methylbenzyl chlor 4-Methyl chloride alpha-Chloro-p-xylene, 99+% 100ML alpha-Chloro-p-xylene, p-Xylyl chloride, 1-(Chloromethyl)-4-methylbenzene The Methyl benzyl chloride α-Chloro-p-xylene, 99+% oro-p-xyL pha-ChL 1-chloromethyl-4-methyl-benzene 1-Methyl-4-(chloromethyl)benzene 4-(Chloromethyl)toluene alpha-chloro-p-xylen p-(chloromethyl)toluene p-Chloromethyltoluene p-tolylmethylchloride p-Xylene, alpha-chloro- p-Xylyl-alpha-chloride α-chloro-p-xylene Benzene, 1-(chloromethyl)-4-methyl- α-Chloro-p-xylene > Plerixafor Impurity 49 α-Chloro-p-methyltoluene P-methyl Benzyl Choride(Pmbc) TIANFU-CHEM 4-Methylbenzyl chloride 104-82-5 Plerixafor Impurity 40 Pulesafu impurity 40 α-Chloro-p-xylene in isooctane 4-Methylbenzyl chloride, 98% a-Chloro-p-methyltoluene 1-(Chloromethyl)-4-methylbenzene 104-82-5 Building Blocks BENZYL HALIDE Halogenated Hydrocarbons