[2H6]-Isradipine
![[2H6]-Isradipine Structure](CAS/20211123/GIF/1261398-97-3.gif)
- CAS No.
- 1261398-97-3
- Chemical Name:
- [2H6]-Isradipine
- Synonyms
- [2H6]-Isradipine;Isradipine-[D6] (Standard);Isradipine D6Q: What is Isradipine D6 Q: What is the CAS Number of Isradipine D6 Q: What is the storage condition of Isradipine D6
- CBNumber:
- CB18011658
- Molecular Formula:
- C19H21N3O5
- Molecular Weight:
- 371.39
- MDL Number:
- MOL File:
- 1261398-97-3.mol
[2H6]-Isradipine Chemical Properties, Uses, Production
Uses
Isradipine-d6 is the deuterium labeled Isradipine[1]. Isradipine (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease[2][3][4].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Ilijic E, et al. The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease. Neurobiol Dis. 2011;43(2):364-371. DOI:10.1016/j.nbd.2011.04.007
[3] Campbell CA, et al. Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats. Exp Neurol. 1997;148(1):45-50. DOI:10.1006/exnr.1997.6611
[4] Hof RP, et al. Selective effects of PN 200-110 (isradipine) on the peripheral circulation and the heart. Am J Cardiol. 1987;59(3):30B-36B. DOI:10.1016/0002-9149(87)90079-8
[2H6]-Isradipine Preparation Products And Raw materials
Raw materials
Preparation Products
[2H6]-Isradipine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Manhag Testing Technology Co., Ltd | 400-818 0104 18918165978 | yanyan.guo@bestown.net.cn | China | 7770 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9894 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Supplier | Advantage |
|---|---|
| Manhag Testing Technology Co., Ltd | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 58 |
| TargetMol | 58 |
