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1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL-

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- structure

CAS No.: 23612-48-8

Chemical Name:: 1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL-

Synonyms: SW-79;SWF-79;2-Methyl-7-azaindole;2-Methyl-7-azaindole 98%;2-Methyl-7-azaindole ,99%;2-Methyl-7-azaindole ,98.5%;2-Methyl-7-azaindole, 98.5%, 98.5%;2-METHYL-1H-PYRROLO[2,3-B]-PYRIDINE;1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL-

CBNumber:: CB1821714

Molecular Formula:: C8H8N2

Molecular Weight:: 132.16

MDL Number:: MFCD08669524

MOL File:: 23612-48-8.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:48

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1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- Properties

Melting point	136-142℃
Density	1.17
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	14.45±0.40(Predicted)
color	Brown
CAS DataBase Reference	23612-48-8

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
HS Code	29339900

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M321420	2-Methyl-7-Azaindole	23612-48-8	50mg	$45	2021-12-16	Buy
TRC	M321420	2-Methyl-7-Azaindole	23612-48-8	500mg	$85	2021-12-16	Buy
Matrix Scientific	068846	2-Methyl-1H-pyrrolo[2,3-b]pyridine >95%	23612-48-8	5g	$195	2021-12-16	Buy
Matrix Scientific	068846	2-Methyl-1H-pyrrolo[2,3-b]pyridine >95%	23612-48-8	1g	$75	2021-12-16	Buy
SynQuest Laboratories	3H32-1-33	2-Methyl-7-azaindole 95%	23612-48-8	1g	$75	2021-12-16	Buy

Product number	Packaging	Price	Buy
M321420	50mg	$45	Buy
M321420	500mg	$85	Buy
068846	5g	$195	Buy
068846	1g	$75	Buy
3H32-1-33	1g	$75	Buy

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

2-Methyl-7-Azaindole can be used to fingerprint volatile profile of traditional tobacco and e-cigarettes.

Synthesis

78191-00-1

138343-75-6

23612-48-8

Under nitrogen protection, tert-butyl 3-methylpyridin-2-ylcarbamate (5.07 g, 23.6 mmol) was dissolved in 100 mL of tetrahydrofuran and the mixture was cooled to -10 °C. Under stirring, n-butyllithium (2.5 M hexane solution, 28 mL, 70 mmol) was slowly added over 15 min and the reaction solution turned dark red, and stirring was continued at -10 °C for 1 hr. Subsequently, N-methoxy-N-methylacetamide (3.80 g, 35.7 mmol) was added and the mixture was warmed to room temperature and stirred for 1 hour. Upon completion of the reaction, the mixture was cooled again to -10 °C, the reaction was quenched with 13 mL of concentrated hydrochloric acid, and then stirred at 50 °C for 90 min. After the two-phase mixture was cooled, the organic phase was separated and extracted twice with 2N hydrochloric acid. The aqueous phases were combined, alkalized to the proper pH with 32% sodium hydroxide solution and subsequently extracted three times with ethyl acetate. The organic phases were combined, washed with saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by Isolera purification system (ethyl acetate-hexane gradient, 0:100 ascending to 50:50) to afford 2-methyl-7-azaindole (2.5 g, 18.9 mmol, 80% yield) as a light yellow solid with 100% purity.1H NMR (400 MHz, CDCl3) δ ppm 2.55 (s, 3H, Me) 6.17 (s, 1H, H-3), 7.03 (dd, J = 4.9, 7.6 Hz, 1H, H-5), 7.82 (d, J = 7.4 Hz, 1H, H-4), 8.21 (d, J = 4.7 Hz, 1H, H-6), 11.96 (br.s, 1H, NH).UPLC/MS (3 min) retention time 0.68 min. LRMS: m/z 133 (M + 1).

References

[1] European Journal of Medicinal Chemistry, 2016, vol. 113, p. 102 - 133

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- Preparation Products And Raw materials

Raw materials

Hexane N-Methylaniline Di-tert-butyl dicarbonate 2-Amino-3-picoline Isopropyl acetate

Tetrahydrofuran Ethyl acetate Hydrochloric acid Dichloromethane Sodium hydroxide

L(+)-Tartaric acid N,N-Dimethylacetamide n-Butyllithium

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Preparation Products

1H-Pyrrolo[2,3-b]pyridine-3-carboxaldehyde, 2-methyl- 2-Methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- Suppliers

Global( 141)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	904	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29800	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58

Supplier	Advantage
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Shanghai Arbor Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Antai Fine Chemical Technology Co.,Limited	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from 1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-05	1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- 23612-48-8	US $1.00 / KG	1IU	99%	1kg-1000kg	Career Henan Chemical Co

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL-
23612-48-8
US $1.00 / KG
99%
Career Henan Chemical Co

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- Spectrum

1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL-(23612-48-8)¹HNMR

23612-48-8(1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL-)Related Search:

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1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL- 2-METHYL-1H-PYRROLO[2,3-B]-PYRIDINE 2-Methyl-7-azaindole 2-Methyl-7-azaindole ,99% 2-Methyl-7-azaindole ,98.5% 2-Methyl-7-azaindole, 98.5%, 98.5% SWF-79 SW-79 2-Methyl-7-azaindole 98% 23612-48-8 Azaindoles