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(E)-4-tert-Butoxy-4-oxobut-2-enoic acid

CAS No.
135355-96-3
Chemical Name:
(E)-4-tert-Butoxy-4-oxobut-2-enoic acid
Synonyms
tert-Butyl fumarate;FuMaric Acid tert-Butyl Ester;4-Isoxazoleethanol,3,9-dimethyl-;Fumaric acid mono-tert-butyl ester;1,3-Propanediol,1-(9-piperidinyl)-;Fumaric Acid tert-Butyl Ester (>90%);(E)-3-t-butoxycarbonyl-2-butenoic acid;(E)-4-tert-Butoxy-4-oxobut-2-enoic acid;2(1H)-Quinolinone,3,4-dihydro-10-hydroxy-;(E)-4-(tert-Butoxy)-4-oxo-2-butenoic Acid
CBNumber:
CB1829154
Molecular Formula:
C8H12O4
Molecular Weight:
172.18
MDL Number:
MFCD08669525
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-09-12 18:50:06

(E)-4-tert-Butoxy-4-oxobut-2-enoic acid Properties

Melting point 65-68 °C
Boiling point 273.8±23.0 °C(Predicted)
Density 1.130±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated
form Solid
pka 3.35±0.10(Predicted)
color White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

(E)-4-tert-Butoxy-4-oxobut-2-enoic acid price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-F500395-5G Fumaric Acid tert-Butyl Ester (>90%) 135355-96-3 5g $1151 2026-06-03 Buy
TRC TRC-F500395-500MG Fumaric Acid tert-Butyl Ester (>90%) 135355-96-3 500mg $162 2026-06-03 Buy
Usbiological 164248 Fumaric Acid tert-Butyl Ester 135355-96-3 500mg $403 2026-06-03 Buy
TRC TRC-F500395-25G Fumaric Acid tert-Butyl Ester (>90%) 135355-96-3 25g $2043 2026-06-03 Buy
Synthonix B47037 (E)-4-(tert-Butoxy)-4-oxobut-2-enoic acid 95+% 135355-96-3 250mg $27 2026-05-06 Buy
Product number Packaging Price Buy
TRC-F500395-5G 5g $1151 Buy
TRC-F500395-500MG 500mg $162 Buy
164248 500mg $403 Buy
TRC-F500395-25G 25g $2043 Buy
B47037 250mg $27 Buy

(E)-4-tert-Butoxy-4-oxobut-2-enoic acid Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

Fumaric Acid tert-Butyl Ester is a tert-Butyl ester derivative of Fumaric Acid (F500380). Fumaric Acid tert-Butyl Ester is a reactant used in the preparation of cysteine protease inhibitors based on fumaric acid-derived oligopeptides. It is also used in the preparation of Nε-fumaroylated diketopiperazine of L-Lys used for pulmonary drug delivery.

Uses

Fumaric acid tert-Butyl ester is a tert-Butyl ester derivative of Fumaric Acid (F500380), it is a reactant used in the preparation of cysteine protease inhibitors based on fumaric acid-derived oligopeptides. It is also used in the preparation of Nε-fumaroylated diketopiperazine of L-Lys used for pulmonary drug delivery.

(E)-4-tert-Butoxy-4-oxobut-2-enoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 66)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2297 55
Shanghai potentpharm CO.,Ltd 13524892556 sales-cn@potentpharm.com China 1011 55
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8039 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
DebyeTec.com Inc. 18086626237 18086626237 2693528373@qq.com China 2936 56

View Latest Price from (E)-4-tert-Butoxy-4-oxobut-2-enoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	(E)-4-TERT-BUTOXY-4-OXOBUT-2-ENOIC ACID pictures 2026-09-02 (E)-4-TERT-BUTOXY-4-OXOBUT-2-ENOIC ACID
135355-96-3
$2.00-8.00 1kg 99% Henan Fengda Chemical Co., Ltd

(E)-4-tert-Butoxy-4-oxobut-2-enoic acid Spectrum

Fumaric acid mono-tert-butyl ester FuMaric Acid tert-Butyl Ester (E)-4-(tert-Butoxy)-4-oxo-2-butenoic Acid 2-Butenedioic acid (2E)-, 1-(1,1-dimethylethyl) ester 2-Butenedioicacid,mono(1,1-dimethylethyl)ester,(2E)- 4-Isoxazoleethanol,3,9-dimethyl- 1,3-Propanediol,1-(9-piperidinyl)- 2(1H)-Quinolinone,3,4-dihydro-10-hydroxy- tert-Butyl fumarate (E)-4-[(2-methylpropan-2-yl)oxy]-4-oxobut-2-enoic acid (E)-3-t-butoxycarbonyl-2-butenoic acid Fumaric Acid tert-Butyl Ester (>90%) (E)-4-tert-Butoxy-4-oxobut-2-enoic acid 135355-96-3 Aliphatics, Metabolites & Impruities, Pharmaceuticals, Intermediates & Fine Chemicals