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ChemicalBook >> CAS DataBase List >>1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)-

1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)-

1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- Structure
1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- structure
CAS No.
205255-11-4
Chemical Name:
1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)-
Synonyms
KN 1022;1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)-
CBNumber:
CB18851359
Molecular Formula:
C21H22N6O5
Molecular Weight:
438.44
MDL Number:
MOL File:
205255-11-4.mol
Last updated:2025-09-11 22:01:37
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1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- Properties

Melting point 272-274 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Boiling point 711.1±60.0 °C(Predicted)
Density 1.406±0.06 g/cm3(Predicted)
pka 12.73±0.70(Predicted)

1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- Chemical Properties,Uses,Production

Uses

KN1022 an inhibitor of phosphorylation of platelet-derived growth factor receptor (PDGFR) with IC50 of 0.24 μM[1].

References

[1] Kenji Matsuno, et al. Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives. J Med Chem. 2002 Jul 4;45(14):3057-66. DOI:10.1021/jm010428o

1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9954 58
InvivoChem 13549236410 sales@invivochem.cn China 6753 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29547 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd 025-58851090 17714375163 2881759498@qq.com China 13011 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 6710 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Shanghai Chaolan Chemical Technology Center 58
InvivoChem 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd 58
Sangon Biotech (Shanghai) Co.,Ltd. 58

View Lastest Price from 1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
KN1022 pictures 2025-09-11 KN1022
205255-11-4
 US $70.00-236.00 / mg 99.88% 10g TargetMol Chemicals Inc.
  • KN1022 pictures
  • KN1022
    205255-11-4
  • US $70.00-236.00 / mg
  • 99.88%
  • TargetMol Chemicals Inc.
1-Piperazinecarboxamide, 4-(6,7-dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)- KN 1022 205255-11-4