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adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid

adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid Structure
adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid structure
CAS No.
3469-78-1
Chemical Name:
adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid
Synonyms
AMP-P(CH2)P;AMP PCP,AMPPCP;Einecs 222-435-7;β,γ-MethyleneATP;β,γ-Methylene ATP;Adenylyl methylenediphosphonate;5'-adenylyl (beta,gamma-methylene)diphosphonate;5'-Adenylic acid (phosphonomethyl)phosphonyl ester;ADENOSINE 5 -MONOPHOSPHATE MONOANHYDRIDE WITH (P...;5'-Adenylic acid, monohydride with methylenebis(phosphonic acid)
CBNumber:
CB1892808
Molecular Formula:
C11H18N5O12P3
Molecular Weight:
505.21
MDL Number:
MFCD05662223
MOL File:
3469-78-1.mol
MSDS File:
SDS
Last updated:2025-07-03 21:36:14
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adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid Properties

Boiling point 968.2±75.0 °C(Predicted)
Density 2.50±0.1 g/cm3(Predicted)
pka 0.68±0.10(Predicted)

adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid Chemical Properties,Uses,Production

Uses

AMP-PCP is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP binding favors the formation of the active homodimer of Hsp90[1].

Definition

ChEBI: Adenosine 5'-[beta,gamma-methylene]triphosphate is a nucleoside triphosphate analogue.

IC 50

HSP90: 3.8 μM (Kd)

References

[1] Zhang H, et al. A dynamic view of ATP-coupled functioning cycle of Hsp90 N-terminal domain. Sci Rep. 2015 Apr 13;5:9542. DOI:10.1038/srep09542

adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid Suppliers

Global( 8)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
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Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29770 58
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Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12000 58
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TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
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Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

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AMP-PCP pictures 2025-07-03 AMP-PCP
3469-78-1
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3469-78-1(adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid )Related Search:

Adenosine 5'-monophosphate
adenosine 5'-monophosphate, monoanhydride with (phosphonomethyl)phosphonic acid 5'-adenylyl (beta,gamma-methylene)diphosphonate 5'-Adenylic acid (phosphonomethyl)phosphonyl ester Adenylyl methylenediphosphonate AMP-P(CH2)P β,γ-Methylene ATP β,γ-MethyleneATP 5'-Adenylic acid, monohydride with methylenebis(phosphonic acid) Einecs 222-435-7 AMP PCP,AMPPCP 5'-Adenylic acid, 5'-anhydride with P,P'-methylenediphosphonic acid ADENOSINE 5 -MONOPHOSPHATE MONOANHYDRIDE WITH (P... 3469-78-1