4-iodopropiophenone
- CAS No.
- 31970-26-0
- Chemical Name:
- 4-iodopropiophenone
- Synonyms
- 1-(4-iodophenyl)propan-1-one;4-iodopropiophenone;1-Propanone, 1-(4-iodophenyl)-
- CBNumber:
- CB1947074
- Molecular Formula:
- C9H9IO
- Molecular Weight:
- 260.07
- MDL Number:
- MFCD09813773
- MOL File:
- 31970-26-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P261-P305+P351+P338 |
4-iodopropiophenone price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS46813 | 1-(4-Iodophenyl)propan-1-one 97% | 31970-26-0 | 1g | $213 | 2026-06-04 | Buy |
| Activate Scientific | AS46813 | 1-(4-Iodophenyl)propan-1-one 97% | 31970-26-0 | 5g | $590 | 2026-06-04 | Buy |
| Matrix Scientific | 114038 | 1-(4-Iodophenyl)propan-1-one | 31970-26-0 | 250.00mg | $84 | 2026-05-18 | Buy |
| Matrix Scientific | 114038 | 1-(4-Iodophenyl)propan-1-one | 31970-26-0 | 1.00g | $100 | 2026-05-18 | Buy |
| Matrix Scientific | 114038 | 1-(4-Iodophenyl)propan-1-one | 31970-26-0 | 5.00g | $489 | 2026-05-18 | Buy |
4-iodopropiophenone Chemical Properties, Uses, Production
Synthesis
591-50-4
79-03-8
31970-26-0
Iodobenzene (100 g, 0.49 mol) was placed in a dry 1 L three-necked flask fitted with an N2 inlet and 200 mL of carbon disulfide (CS2) was added to it. The reaction mixture was cooled to 0-5 °C, followed by the addition of anhydrous aluminum trichloride (AlCl3, 80 g, 0.6 mol) in batches, followed by the slow dropwise addition of propionyl chloride (60 g, 0.64 mol) while the reaction temperature was controlled to be maintained at 5-10 °C. The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the mixture was slowly poured into a 5 L plastic beaker containing 1 L of 10% hydrochloric acid (HCl) and 1 kg of crushed ice. The reaction mixture was extracted with 1 L of ethyl acetate and the organic layer was separated and washed sequentially with 2 x 500 mL of water and 500 mL of saturated saline. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure at 40 °C to give 4'-iodopropiophenone (48 g, 38% yield). The product was characterized by 1H NMR (500 MHz, CDCl3): δ 7.82 (d, 2H), 7.67 (d, J = 8.30 Hz, 2H), 2.96 (q, J = 7.00 Hz, 2H), 1.22 (t, J = 7.32 Hz, 3H).
References
[1] Patent: WO2010/104488, 2010, A1. Location in patent: Page/Page column 62
[2] Yakugaku Zasshi, 1936, vol. 56, p. 690,696; dtsch. Ref. S. 163, 166
[3] Chem. Zentralbl., 1937, vol. 108, # I, p. 2584
[4] Chemische Berichte, 1941, vol. 74, p. 321,324
4-iodopropiophenone Preparation Products And Raw materials
Raw materials
Preparation Products
4-iodopropiophenone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Shanghai SPAR pharmaceutical technology co., LTD | 021-000000 | admin@jingshipharmatech.com | China | 9917 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Hefei Hangang Pharmaceutical Technology Co., Ltd. | +8618062405514 | ada@ipurechemical.com | China | 10224 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3453 | 58 |
| Zhejiang Lianshuo Biotechnology Co., Ltd. | 18616526224 | lianshuo@vip.126.com | China | 9605 | 58 |
| Shanghai Amico Chemicals Co. LTD | 微信 18019252918 18019252918 | 1454668768@qq.com | China | 14933 | 58 |
