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Thieno[2,3-d]pyrimidin-4(3H)one

Thieno[2,3-d]pyrimidin-4(3H)one structure

CAS No.: 14080-50-3

Chemical Name:: Thieno[2,3-d]pyrimidin-4(3H)one

Synonyms: 3,4-Dihyd;thieno[2,3-d]pyrimidin-4-ol;6-CHLORO-3-FLUORO-1H-INDAZOLE;ieno[2,3-d]pyriMidin-4(3H)one;3H-thieno[2,3-d]pyrimidin-4-one;Thieno[2,3-d]pyrimidin-4(3H)-one;Thieno[2,3-d]pyrimidin-4(1H)-one;3H-Thieno[2,3-d]pyrimidine-4-one;1H,4H-THIENO[2,3-D]PYRIMIDIN-4-ONE;3H-Thieno[2,3-d]pyrimidine-4-one

CBNumber:: CB1956232

Molecular Formula:: C6H4N2OS

Molecular Weight:: 152.17

MDL Number:: MFCD00706456

MOL File:: 14080-50-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:44

Product description	Number	Pack Size	Price
3,4-Dihydro-4-oxothieno[2,3-d]pyrimidine AldrichCPR	JRD0205	1g	$107
Thieno[2,3-d]pyrimidin-4(1H)-one	T3792	1G	$43
Thieno[2,3-d]pyrimidin-4(1H)-one	T3792	5G	$164
4-Hydroxythieno[2,3-d]pyrimidine	H961750	500mg	$50
4-Hydroxythieno[2,3-d]pyrimidine	H961750	10g	$620
More product size

Request For Quotation

Thieno[2,3-d]pyrimidin-4(3H)one Properties

Melting point	262-265°C
Boiling point	391.1±15.0 °C(Predicted)
Density	1.63±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in DMSO, Methanol
form	powder to crystal
pka	10.84±0.20(Predicted)
color	Light yellow to Brown
InChI	InChI=1S/C6H4N2OS/c9-5-4-1-2-10-6(4)8-3-7-5/h1-3H,(H,7,8,9)
InChIKey	JEDVKUHCDPPWNR-UHFFFAOYSA-N
SMILES	C1=NC(=O)C2C=CSC=2N1
CAS DataBase Reference	14080-50-3
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Codes

Xi,Xn

Risk Statements

WGK Germany

HS Code

2934999090

NFPA 704

	0
2		0

Thieno[2,3-d]pyrimidin-4(3H)one price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	JRD0205	3,4-Dihydro-4-oxothieno[2,3-d]pyrimidine AldrichCPR	14080-50-3	1g	$107	2025-07-31	Buy
TCI Chemical	T3792	Thieno[2,3-d]pyrimidin-4(1H)-one	14080-50-3	1G	$43	2025-07-31	Buy
TCI Chemical	T3792	Thieno[2,3-d]pyrimidin-4(1H)-one	14080-50-3	5G	$164	2025-07-31	Buy
TRC	H961750	4-Hydroxythieno[2,3-d]pyrimidine	14080-50-3	500mg	$50	2021-12-16	Buy
TRC	H961750	4-Hydroxythieno[2,3-d]pyrimidine	14080-50-3	10g	$620	2021-12-16	Buy

Product number	Packaging	Price	Buy
JRD0205	1g	$107	Buy
T3792	1G	$43	Buy
T3792	5G	$164	Buy
H961750	500mg	$50	Buy
H961750	10g	$620	Buy

Thieno[2,3-d]pyrimidin-4(3H)one Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Uses

4-Hydroxythieno[2,3-d]pyrimidine (cas# 14080-50-3) is a compound useful in organic synthesis.

Synthesis

4651-81-4

77287-34-4

14080-50-3

Thieno[2,3-d]pyrimidin-4(3H)-one was synthesized from methyl 2-aminothiophene-3-carboxylate (3.0 g, 19.1 mmol) and formamide (95 ml) by heating and reacting at 190 °C for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and poured into water. The precipitate was collected by filtration, washed with water and dried. The crude product was purified by silica gel column chromatography (eluent: CH2Cl2/MeOH = 50:1) to afford the target compound thieno[2,3-d]pyrimidin-4(3H)-one as a white solid (1.93 g, 66% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO, 25 °C) and HRMS: 1H NMR δ= 12.49 (s, 1H, NH), 8.13 (s, 1H, CH), 7.58 (d, J = 5.8 Hz, 1H, CH), 7.39 (d, J = 5.8 Hz, 1H, CH) ppm; HRMS (calculated) C6H5N2OS: 153.01226, measured value: 153.01155).

References

[1] Patent: US2012/46278, 2012, A1. Location in patent: Page/Page column 81
[2] Patent: US2013/190297, 2013, A1. Location in patent: Paragraph 1205; 1206; 1207
[3] Patent: US2014/88088, 2014, A1. Location in patent: Paragraph 1220-1222
[4] Patent: CN107573386, 2018, A. Location in patent: Paragraph 0048-0050
[5] Tetrahedron, 2012, vol. 68, # 45, p. 9226 - 9233

Thieno[2,3-d]pyrimidin-4(3H)one Preparation Products And Raw materials

Raw materials

Ethyl 2-aminothiophene-3-carboxylate Methyl 2-aminothiophene-3-carboxylate Formamidine acetate formamide

Preparation Products

5-bromo-4-chlorothieno[2,3-d]pyrimidine 4-bromothieno[2,3-d]pyrimidine

Thieno[2,3-d]pyrimidin-4(3H)one Suppliers

Global( 201)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29839	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	967	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58

View Lastest Price from Thieno[2,3-d]pyrimidin-4(3H)one manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-06-25	Thieno[2,3-d]pyrimidin-4(3H)one 14080-50-3	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2025-04-04	Thieno[2,3-d]pyrimidin-4(3H)one 14080-50-3	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2019-07-10	Thieno[2,3-d]pyrimidin-4(3H)one 14080-50-3	US $8.80 / KG	1KG	97%-99%	100kg	Career Henan Chemical Co

Thieno[2,3-d]pyrimidin-4(3H)one
14080-50-3
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

Thieno[2,3-d]pyrimidin-4(3H)one
14080-50-3
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

Thieno[2,3-d]pyrimidin-4(3H)one
14080-50-3
US $8.80 / KG
97%-99%
Career Henan Chemical Co

Thieno[2,3-d]pyrimidin-4(3H)one Spectrum

Thieno[2,3-d]pyrimidin-4(3H)one(14080-50-3)¹HNMR

14080-50-3(Thieno[2,3-d]pyrimidin-4(3H)one)Related Search:

2,4-Dihydroxythieno[2,3-d]pyrimidine THIENO[2,3-B]PYRAZIN-7-AMINE Thieno[3,2-d]pyrimidine-4-carboxylic acid Thieno[2,3-b]pyridine (8CI,9CI) thieno[2,3-b]pyridin-4-ol

Methyl thieno[2,3-b]pyridine-2-carboxylate thieno[2,3-d]thiazol-2-amine 5-[(tert-butoxy)carbonyl]-3-Methyl-4H,5H,6H,7H- thieno[3,2-c]pyridine-2-carboxylic acid ethyl 3-aMino-6-(trifluoroMethyl)thieno[2,3- b]pyridine-2-carboxylate 4-HYDROXYTHIENO[3,2-C]PYRIDINE

4-CHLOROTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE THIENO[3,2-D]PYRIMIDIN-4(3H)-ONE Thiazolo[5,4-c]pyridin-2-amine, 6-methoxy- 7-BROMOTHIENO[3,2-D]PYRIMIDIN-4(1H)-ONE 2-(TRIFLUOROMETHYL)THIENO[3,2-D]PYRIMIDIN-4-OL

1,3-Dihydrothiopheno[3,2-d]pyrimidine-2,4-dione 5-(4-FLUOROPHENYL)-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE 5-thien-2-ylthieno[2,3-d]pyrimidin-4(3H)-one

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4-Hydroxythieno[2,3-d]pyrimidine, Thieno[2,3-d]pyrimidin-4(1H)-one Thieno[2,3-d]pyrimidin-4(1H)-one 3,4-Dihyd Thieno[2,3-d]pyrimidin-4(3H)-one thieno[2,3-d]pyrimidin-4-ol 3H-Thieno[2,3-d]pyrimidine-4-one ieno[2,3-d]pyriMidin-4(3H)one 3,4-Dihydro-4-oxothieno[2,3-d]pyrimidine 3H-Thieno[2,3-d]pyrimidine-4-one 6-CHLORO-3-FLUORO-1H-INDAZOLE 1H,4H-THIENO[2,3-D]PYRIMIDIN-4-ONE Thieno[2,3-d]pyrimidin-4(3H)one ISO 9001：2015 REACH 3H-thieno[2,3-d]pyrimidin-4-one Thieno[2,3-d]pyrimidin-4(1H)-one (9CI, ACI) Thiopheno [2,3-d] pyrimidin-4 (3H) - one Thieno-[2, 3-d] pyrimidine-4 (3H) -ketone 3,4-Dihydro-4-oxothieno[2,3-d]pyrimidine 14080-50-3 Fused Ring Systems Bases & Related Reagents Heterocycles Nucleotides Thiophene