Boc-S-trityl-D-cysteine
- CAS No.
- 87494-13-1
- Chemical Name:
- Boc-S-trityl-D-cysteine
- Synonyms
- Boc-Cys(trt)-OH;BOC-D-CYS(TRT)-OH 98%;Boc-S-trityl-D-cysteine;N-Boc-S-trityl-D-cysteine;Boc-D-Cys(Trt)-OH（non-animal）;N-Boc-S-trityl-D-cysteine, 98%;Boc-S-trityl-D-cysteine USP/EP/BP;(Tert-Butoxy)Carbonyl D-Cys(Trt)-OH;Boc-S-trityl-D-cysteine≥ 99% (HPLC);Boc-D-Cys(Trt)-OH Boc-S-trityl-D-cysteine
- CBNumber:
- CB1966770
- Molecular Formula:
- C27H29NO4S
- Molecular Weight:
- 463.59
- MDL Number:
- MFCD00236839
- MOL File:
- 87494-13-1.mol
- MSDS File:
- SDS
| Melting point | 146-149°C |
|---|---|
| Boiling point | 610.9±55.0 °C(Predicted) |
| Density | 1.200±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly) |
| form | Solid |
| pka | 3.82±0.10(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 87494-13-1 |
| UNSPSC Code | 12352209 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| NFPA 704 |
|
Boc-S-trityl-D-cysteine price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B600660 | Boc-D-Cys(Trt)-OH | 87494-13-1 | 5g | $150 | 2021-12-16 | Buy |
| Iris Biotech GmbH | BAA5000 | Boc-D-Cys(Trt)-OH | 87494-13-1 | 5G | $135 | 2021-12-16 | Buy |
| Activate Scientific | AS102944 | Boc-S-trityl-D-cysteine 95% ee | 87494-13-1 | 5G | $147 | 2021-12-16 | Buy |
| ChemPep | 110503 | Boc-D-Cys(Trt)-OH ≥98% | 87494-13-1 | 5g | $218 | 2021-12-16 | Buy |
| Matrix Scientific | 093648 | Boc-D-Cys(Trt)-OH 95+% | 87494-13-1 | 1g | $227 | 2021-12-16 | Buy |
Boc-S-trityl-D-cysteine Chemical Properties,Uses,Production
Uses
Boc-Cys(Trt)-OH is used in method for preparing ularitide.
reaction suitability
reaction type: Boc solid-phase peptide synthesis
Synthesis
24424-99-5
2799-07-7
21947-98-8
General procedure for the synthesis of N-tert-butoxycarbonyl-S-trityl-L-cysteine from di-tert-butyl dicarbonate and S-trityl-L-cysteine: to a solution of 2N NaOH (80 mL) of S-trityl-L-cysteine (5 g, 12.7 mmol) was added di-tert-butyl dicarbonate (4.5 g, 20 mmol), and the reaction mixture was at room temperature The reaction mixture was stirred for 24 hours at room temperature. Upon completion of the reaction, the aqueous solution was acidified to pH 2 with concentrated HCl and then extracted with CH2Cl2 (2 x 100 mL). The organic phases were combined, washed with brine, dried and concentrated under reduced pressure to give N-Boc-S-trityl-L-cysteine (5.3 g, 90%) as a white foam, which did not need to be further purified.1H NMR (DMSO): δ (ppm) 1.37 (s, 9H, 3 × CH3); 2.29-2.58 (m, 2H, CH2); 3.76- 3.79 (m, 1H, CH); 6.84 (d, J = 7.8 Hz, 1H, NH); 7.14-7.38 (m, 15H, triphenylmethyl-H).MALDI-TOF MS: m/z 464.8 Da [M + H], C27H29NO4S, molecular weight: 463.59.
References
[1] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 383 - 392
[2] Chemical Communications, 2013, vol. 49, # 92, p. 10808 - 10810
[3] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0096; 0100; 0101; 0102; 0142; 0146; 0147; 0148
[4] Patent: WO2009/137251, 2009, A2. Location in patent: Page/Page column 30; 31
[5] Chemistry of Natural Compounds, 1979, vol. 15, p. 471 - 476
Boc-S-trityl-D-cysteine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from Boc-S-trityl-D-cysteine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Boc-S-trityl-D-cysteine
87494-13-1
|
US $1.00 / KG | 1KG | 99% | 20kg | Career Henan Chemical Co |
-
- Boc-S-trityl-D-cysteine
87494-13-1
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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