3-BROMO-5-HYDROXYBENZOIC ACID
- CAS No.
- 140472-69-1
- Chemical Name:
- 3-BROMO-5-HYDROXYBENZOIC ACID
- Synonyms
- 3-BROMO-5-HYDROXYBENZOIC ACID;5-Hydroxy-3-bromobenzoic acid;Benzoic acid, 3-broMo-5-hydroxy-;3-BroMo-5-hydroxybenzoic acid 97%;3-
BroMo- 5- hydroxybenzoic acid
- CBNumber:
- CB1972245
- Molecular Formula:
- C7H5BrO3
- Molecular Weight:
- 217.02
- MDL Number:
- MFCD06797980
- MOL File:
- 140472-69-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Bromo-5-hydroxybenzoic acid 97% | 686417 | 5g | $73.1 |
| 3-Bromo-5-hydroxybenzoic Acid >98.0%(GC)(T) | B4740 | 1g | $42 |
| 3-Bromo-5-hydroxybenzoic Acid >98.0%(GC)(T) | B4740 | 5g | $124 |
| 3-Bromo-5-hydroxybenzoic acid | B699128 | 250mg | $55 |
| 3-Bromo-5-hydroxybenzoic acid | B699128 | 500mg | $65 |
| More product size | |||
| Melting point | 237-241 °C |
|---|---|
| Boiling point | 388.1±32.0 °C(Predicted) |
| Density | 1.861±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 3.69±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C7H5BrO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9H,(H,10,11) |
| InChIKey | WGIBEMRBLBGETQ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(O)=CC(Br)=C1 |
| CAS DataBase Reference | 140472-69-1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H400 | |||||||||
| Precautionary statements | P273-P301+P310+P330 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-50 | |||||||||
| Safety Statements | 61 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2918290090 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Aquatic Acute 1 |
|||||||||
| NFPA 704 |
|
3-BROMO-5-HYDROXYBENZOIC ACID price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 686417 | 3-Bromo-5-hydroxybenzoic acid 97% | 140472-69-1 | 5g | $73.1 | 2026-03-19 | Buy |
| TCI Chemical | B4740 | 3-Bromo-5-hydroxybenzoic Acid >98.0%(GC)(T) | 140472-69-1 | 1g | $42 | 2026-03-19 | Buy |
| TCI Chemical | B4740 | 3-Bromo-5-hydroxybenzoic Acid >98.0%(GC)(T) | 140472-69-1 | 5g | $124 | 2026-03-19 | Buy |
| TRC | B699128 | 3-Bromo-5-hydroxybenzoic acid | 140472-69-1 | 250mg | $55 | 2021-12-16 | Buy |
| TRC | B699128 | 3-Bromo-5-hydroxybenzoic acid | 140472-69-1 | 500mg | $65 | 2021-12-16 | Buy |
3-BROMO-5-HYDROXYBENZOIC ACID Chemical Properties,Uses,Production
Uses
3-Bromo-5-hydroxybenzoic acid is a carboxylic acid derivative and is used in organic synthesis.
Synthesis Reference(s)
[1] Leukotriene b4 inhibitors. Patent no. US20100240678A1
Synthesis
To a solution of NaOH (12.2 g; 305.8 mmol) in 300 mL of water was added 3-bromo-5-iodo-benzoic acid (20 g, 61.2 mmol) and Cu2O (866 mg, 6.1 mmol). The reaction mixture was heated at 100° C. for 24 h. After complete consumption of the starting material, the reaction mixture was cooled to room temperature and filtered through celite. The filtrate was then acidified with 10% aq. HCl and extracted into ethyl acetate. The organic extract was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the 3-Bromo-5-hydroxybenzoic acid as a tan solid (12.3 g, 93% yield).
Purification Methods
The acid crystallises from H2O (m 238-239o), and with Me2SO4 it yields the 3-methoxy derivative with m 190-191o (from EtOH). [Baddar et al. J Chem Soc 469 1955, Beilstein 10 IV 333.]
References
[1] Patent: US2010/240678, 2010, A1. Location in patent: Page/Page column 22
[2] Patent: WO2009/77385, 2009, A1. Location in patent: Page/Page column 63
[3] Patent: WO2005/113494, 2005, A2. Location in patent: Page/Page column 118-119
3-BROMO-5-HYDROXYBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai jinsheng pharma tech co.,ltd | 13585563093 | pinpinzheng@jspharmatech.com | China | 374 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29822 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
View Lastest Price from 3-BROMO-5-HYDROXYBENZOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | 3-BROMO-5-HYDROXYBENZOIC ACID
140472-69-1
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-09-25 | 3-BROMO-5-HYDROXYBENZOIC ACID
140472-69-1
|
US $3.00-0.20 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-05-26 | 3-BROMO-5-HYDROXYBENZOIC ACID
140472-69-1
|
US $9.00 / KG | 1KG | 99.9 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 3-BROMO-5-HYDROXYBENZOIC ACID
140472-69-1
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3-BROMO-5-HYDROXYBENZOIC ACID
140472-69-1
- US $3.00-0.20 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 3-BROMO-5-HYDROXYBENZOIC ACID
140472-69-1
- US $9.00 / KG
- 99.9
- Hebei Chuanghai Biotechnology Co,.LTD
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