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Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) structure

CAS No.: 167465-99-8

Chemical Name:: Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)

Synonyms: tert-Butyl ((1S,3R);(1R,3S)-3-aminocyclopentan-1-ol;(1R,3S)-3-(Boc-amino)cyclopentanol;Benzoicacid,6-ethynyl-,methylester;cis-tert-butyl-3-hydroxycyclopentylcarbamate;(1S,3R)-tert-butyl(3-hydroxycyclopentyl)catbaMte;(1S,3R)-3-Hydroxycyclopentyl] tert-butyl carbamate;tert-butyl N-[(1S,3R)-3-hydroxycyclopentyl]carbamate;[(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester;tert-Butyl ((1S,3R)-3-hydroxycyclopentyl)carbamate - H10877

CBNumber:: CB21060890

Molecular Formula:: C10H19NO3

Molecular Weight:: 201.26

MDL Number:: MFCD11878011

MOL File:: 167465-99-8.mol

Last updated:2025-07-24 18:13:44

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Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Properties

Boiling point	321℃
Density	1.08
Flash point	148℃
storage temp.	2-8°C
pka	12.27±0.40(Predicted)
Appearance	White to off-white Solid
InChI	InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-7-4-5-8(12)6-7/h7-8,12H,4-6H2,1-3H3,(H,11,13)/t7-,8+/m0/s1
InChIKey	SBUKINULYZANSP-JGVFFNPUSA-N
SMILES	C(OC(C)(C)C)(=O)N[C@H]1CC[C@@H](O)C1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B814475	tert-Butyl((1S,3R)-3-Hydroxycyclopentyl)carbamate	167465-99-8	50mg	$65	2021-12-16	Buy
ChemScene	CS-W019801	Carbamicacid,N-[(1S,3R)-3-hydroxycyclopentyl]-,1,1-dimethylethylester 99.75%	167465-99-8	100mg	$67	2021-12-16	Buy
Biosynth Carbosynth	FB141944	tert-Butyl ((1S,3R)-3-hydroxycyclopentyl)carbamate	167465-99-8	50mg	$71	2021-12-16	Buy
ChemScene	CS-W019801	Carbamicacid,N-[(1S,3R)-3-hydroxycyclopentyl]-,1,1-dimethylethylester 99.75%	167465-99-8	250mg	$111	2021-12-16	Buy
Biosynth Carbosynth	FB141944	tert-Butyl ((1S,3R)-3-hydroxycyclopentyl)carbamate	167465-99-8	100mg	$124	2021-12-16	Buy

Product number	Packaging	Price	Buy
B814475	50mg	$65	Buy
CS-W019801	100mg	$67	Buy
FB141944	50mg	$71	Buy
CS-W019801	250mg	$111	Buy
FB141944	100mg	$124	Buy

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Uses,Production

Synthesis

Tert-Butyl 2-Oxa-3-Azabicyclo[2.2.1]Hept-5-Ene-3-Carboxylate

99027-90-4

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)

167465-99-8

Tert-butyl 2-oxa-3-azabicyclo[2.2.1]hept-5-ene-3-carboxylate (8.0 g, 40.56 mmol, 1.00 eq.) was mixed with palladium/carbon catalyst (0.5 g) in methanol (100 mL). The reaction was stirred at 60 °C for 48 hours under hydrogen atmosphere. Upon completion of the reaction, the mixture was cooled to room temperature and the catalyst was removed by filtration. The catalyst was washed with methanol (3 x 10 mL). The filtrate and washings were combined and concentrated in vacuum to give tert-butyl N-[(1S,3R)-3-hydroxycyclopentyl]carbamate (6.5 g, 80% yield) as a white solid. The product was characterized by 1H NMR (400 MHz, D2O, ppm): δ 4.72 (1H, s), 4.55 (1H, s), 1.92-1.87 (3H, m), 1.76-1.60 (3H, m), 1.50 (9H, s).

References

[1] Patent: WO2013/155338, 2013, A2. Location in patent: Page/Page column 144
[2] Patent: US2015/329503, 2015, A1. Location in patent: Paragraph 0646

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) synthesis

Synthesis of Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) from 1-[(3S,1R)-3-N-BOC-aminocyclopentyl]-1-ethanone

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Tert-Butyl 2-Oxa-3-Azabicyclo[2.2.1]Hept-5-Ene-3-Carboxylate Activated carbon Methanol Palladium Hydrogen

Preparation Products

Carbamic acid, (3-hydroxycyclopentyl)-, 1,1-dimethylethyl ester, (1S-trans)- (1R,3S)-3-AMinocyclopentanol hydrochloride

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Suppliers

Global( 100)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29731	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49733	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29804	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8285	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai UCHEM Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-03	Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) 167465-99-8	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co
	2020-01-03	Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) 167465-99-8	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
167465-99-8
US $1.00 / KG
99%
Career Henan Chemical Co

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)
167465-99-8
US $1.00 / KG
99%
Career Henan Chemical Co

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) Spectrum

Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI)(167465-99-8)¹HNMR

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Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (1R,3S)-3-(Boc-amino)cyclopentanol Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester (9CI) [(1S,3R)-3-Hydroxycyclopentyl]carbamic acid tert-butyl ester (1R,3S)-3-aminocyclopentan-1-ol (1S,3R)-tert-butyl(3-hydroxycyclopentyl)catbaMte cis-tert-butyl-3-hydroxycyclopentylcarbamate tert-butyl N-[(1S,3R)-3-hydroxycyclopentyl]carbamate [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester Carbamic acid, N-[(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethylethyl ester tert-Butyl ((1S,3R)-3-hydroxycyclopentyl)carbamate - H10877 tert-Butyl ((1S,3R) Carbamic acid, [(1S,3R)-3-hydroxycyclopentyl]-, 1,1-dimethyl... Benzoicacid,6-ethynyl-,methylester (1S,3R)-3-Hydroxycyclopentyl] tert-butyl carbamate 167465-99-8 465-99-8 10772-05-8 N-BOC