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ChemicalBook >> CAS DataBase List >>8-CHLORO-[1,7]NAPHTHYRIDINE

8-CHLORO-[1,7]NAPHTHYRIDINE

8-CHLORO-[1,7]NAPHTHYRIDINE Structure
8-CHLORO-[1,7]NAPHTHYRIDINE structure
CAS No.
13058-77-0
Chemical Name:
8-CHLORO-[1,7]NAPHTHYRIDINE
Synonyms
8-Chloro-1,7phthyridine;8-CHLORO-[1,7]NAPHTHYRIDINE;1,7-Naphthyridine, 8-chloro-;8-chloro-1,7-naphthyridine - [C82253]
CBNumber:
CB2109758
Molecular Formula:
C8H5ClN2
Molecular Weight:
164.59
MDL Number:
MFCD08437452
MOL File:
13058-77-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:40
Product description Number Pack Size Price
8-chloro-1,7-naphthyridine 190200 100.00mg $46
8-chloro-1,7-naphthyridine 190200 250.00mg $95
8-chloro-1,7-naphthyridine 190200 1.00g $326
8-chloro-1,7-naphthyridine 97% C82253 100mg $65
8-chloro-1,7-naphthyridine 97% C82253 250mg $80
More product size
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8-CHLORO-[1,7]NAPHTHYRIDINE Properties

Boiling point 307.9±22.0 °C(Predicted)
Density 1.349±0.06 g/cm3(Predicted)
storage temp. 2-8°C, stored under nitrogen
pka 1.54±0.30(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2933998090

8-CHLORO-[1,7]NAPHTHYRIDINE price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 190200 8-chloro-1,7-naphthyridine 13058-77-0 100.00mg $46 2026-05-18 Buy
Matrix Scientific 190200 8-chloro-1,7-naphthyridine 13058-77-0 250.00mg $95 2026-05-18 Buy
Matrix Scientific 190200 8-chloro-1,7-naphthyridine 13058-77-0 1.00g $326 2026-05-18 Buy
Synthonix C82253 8-chloro-1,7-naphthyridine 97% 13058-77-0 100mg $65 2026-05-06 Buy
Synthonix C82253 8-chloro-1,7-naphthyridine 97% 13058-77-0 250mg $80 2026-05-06 Buy
Product number Packaging Price Buy
190200 100.00mg $46 Buy
190200 250.00mg $95 Buy
190200 1.00g $326 Buy
C82253 100mg $65 Buy
C82253 250mg $80 Buy

8-CHLORO-[1,7]NAPHTHYRIDINE Chemical Properties,Uses,Production

Synthesis

7H-1,7-NAPHTHYRIDIN-8-ONE

67967-11-7

8-CHLORO-[1,7]NAPHTHYRIDINE

13058-77-0

General procedure for the synthesis of 8-chloro-1,7-naphthyridine from 1,7-naphthyridin-8(7H)-one: 1,7-naphthyridin-8(7H)-one (2.0 g, 13.7 mmol) was dissolved in phosphorus triclopyr (20 mL) and heated and refluxed at 100 °C for 16 h. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove the solvent. The residue was neutralized by adding saturated sodium bicarbonate solution (20 mL) and subsequently extracted with ethyl acetate (3 x 25 mL). The organic phases were combined, washed with saturated saline (25 mL) and dried over anhydrous sodium sulfate. After filtration, the filtrate was concentrated under reduced pressure and the resulting crude product was purified by silica gel column chromatography to afford 8-chloro-1,7-naphthyridine (1.4 g, 62% yield) using dichloromethane/methanol (98:2 to 95:5, v/v) as eluent. Mass spectrum (EI) m/z: 165.3 ([M+H]+); 1H NMR (400 MHz, DMSO-d6) δ: 7.64 (d, J = 6.0 Hz, 1H), 7.70 (dd, J = 4.0, 8.4 Hz, 1H), 8.22 (dd, J = 1.6, 8.4 Hz, 1H), 8.40 (d, J = 6.0 Hz. 1H), 9.15 (dd, J = 1.6, 4.0 Hz, 1H).

References

[1] Patent: WO2017/14323, 2017, A1. Location in patent: Paragraph 0280

8-CHLORO-[1,7]NAPHTHYRIDINE synthesis

67967-11-7
13058-77-0
Synthesis of 8-CHLORO-[1,7]NAPHTHYRIDINE from 7H-1,7-NAPHTHYRIDIN-8-ONE

8-CHLORO-[1,7]NAPHTHYRIDINE Preparation Products And Raw materials

Raw materials

1,7-NAPHTHYRIDIN-8-AMINE 7H-1,7-NAPHTHYRIDIN-8-ONE 2,3-Diaminopyridine

Preparation Products

8-CHLORO-[1,7]NAPHTHYRIDINE Suppliers

Global( 57)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Nanjing jinheyou Trading Co., Ltd. 		15705188088 admin@jheyou.com CHINA 1268 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9984 58
Aceschem Inc. 		+1-817863-6948 +1-（817）863-6948 sales@aceschem.com United States 19632 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Suzhou ARTK Medchem Co., Ltd. 		+8618118463618 sales1@artkmedchem.com China 39021 58
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
SynAsst Chemical. 021-60343070 China 12740 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 18151128828 hc-sales@foxmail.com China 2641 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
Nanjing jinheyou Trading Co., Ltd. 		58
Coresyn Pharmatech Co., Ltd. 		58
Aceschem Inc. 		58
Aladdin Scientific 		58
Suzhou ARTK Medchem Co., Ltd. 		58
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 56
SynAsst Chemical. 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 55

View Lastest Price from 8-CHLORO-[1,7]NAPHTHYRIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-CHLORO-[1,7]NAPHTHYRIDINE pictures 2019-12-31 8-CHLORO-[1,7]NAPHTHYRIDINE
13058-77-0
 US $0.00 / g 1g 95%min 20kg/month Nanjing jinheyou Trading Co., Ltd.

8-CHLORO-[1,7]NAPHTHYRIDINE Spectrum

8-CHLORO-[1,7]NAPHTHYRIDINE(13058-77-0)1HNMR

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8-CHLORO-[1,7]NAPHTHYRIDINE 8-Chloro-1,7phthyridine 1,7-Naphthyridine, 8-chloro- 8-chloro-1,7-naphthyridine - [C82253] 13058-77-0 pharmacetical