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2-Methyl-4-trifluoromethylimidazole

CAS No.
33468-67-6
Chemical Name:
2-Methyl-4-trifluoromethylimidazole
Synonyms
2-METHYL-4-TRIFLUOROMETHYLIMIDAZOLE;2-Methyl-5-(trifluoromethyl)-1H-imidazole;2-Methyl-4-(trifluoroMethyl)-2H-iMidazole;2-methyl-4-(trifluoromethyl)-1H-imidazole;1H-Imidazole, 2-methyl-4-(trifluoromethyl)-;1H-Imidazole, 2-methyl-5-(trifluoromethyl)-;2-Methyl-5-(trifluoromethyl)-1H-imidazole 95%;2-Methyl-4-trifluoromethyl-1H-imidazole
CBNumber:
CB21120903
Molecular Formula:
C5H5F3N2
Molecular Weight:
150.1
MDL Number:
MFCD10000863
MOL File:
33468-67-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:48
Product description Number Pack Size Price
2-Methyl-4-trifluoromethyl-1H-imidazole MNO000165 1g $185
2-Methyl-4-(trifluoromethyl)-1H-imidazole B486205 500mg $155
2-Methyl-4-trifluoromethyl-1H-imidazole 95% 064636 5g $239
2-Methyl-5-(trifluoromethyl)-1H-imidazole 95% PC48292 5g $260
2-Methyl-5-(trifluoromethyl)-1H-imidazole 97% 3H31-3-25 1g $125
More product size

2-Methyl-4-trifluoromethylimidazole Properties

Melting point 179-180 °C
Boiling point 249 °C
Density 1.355
Flash point 105 °C
storage temp. Sealed in dry,Room Temperature
form solid
pka 10.84±0.10(Predicted)
InChI InChI=1S/C5H5F3N2/c1-3-9-2-4(10-3)5(6,7)8/h2H,1H3,(H,9,10)
InChIKey UTUSYSDVLOWRJA-UHFFFAOYSA-N
SMILES C1(C)NC(C(F)(F)F)=CN=1
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
HazardClass  IRRITANT
HS Code  2933998090

2-Methyl-4-trifluoromethylimidazole price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich MNO000165 2-Methyl-4-trifluoromethyl-1H-imidazole 33468-67-6 1g $185 2025-07-31 Buy
TRC B486205 2-Methyl-4-(trifluoromethyl)-1H-imidazole 33468-67-6 500mg $155 2021-12-16 Buy
Matrix Scientific 064636 2-Methyl-4-trifluoromethyl-1H-imidazole 95% 33468-67-6 5g $239 2021-12-16 Buy
Apolloscientific PC48292 2-Methyl-5-(trifluoromethyl)-1H-imidazole 95% 33468-67-6 5g $260 2021-12-16 Buy
SynQuest Laboratories 3H31-3-25 2-Methyl-5-(trifluoromethyl)-1H-imidazole 97% 33468-67-6 1g $125 2021-12-16 Buy
Product number Packaging Price Buy
MNO000165 1g $185 Buy
B486205 500mg $155 Buy
064636 5g $239 Buy
PC48292 5g $260 Buy
3H31-3-25 1g $125 Buy

2-Methyl-4-trifluoromethylimidazole Chemical Properties,Uses,Production

Synthesis

Acetaldehyde

75-07-0

TRIFLUOROPYRUVIC ALDEHYDE

91944-47-7

2-Methyl-4-trifluoromethylimidazole

33468-67-6

General procedure for the synthesis of 2-methyl-4-trifluoromethylimidazole from acetaldehyde and trifluoromethanesulfonic acid: to a 10 mL sealed tube was added a mixture of acetaldehyde (296 μL, 5.29 mmol), 3,3,3-trifluoro-2-oxopropanal (Compound 16.1, 1.0 g, 7.9 mmol) and 25% ammonium hydroxide solution (0.8 mL) in methanol (5 mL) Solution. The reaction mixture was stirred at 0°C for 3 hours, followed by continued stirring at room temperature overnight. After completion of the reaction, the mixture was concentrated under reduced pressure and the residue was diluted with water (50 mL). The aqueous phase was extracted with ethyl acetate (3 x 20 mL), the organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography to give 430 mg (54% yield) of 2-methyl-4-trifluoromethylimidazole as a light yellow solid.

References

[1] Patent: WO2014/8197, 2014, A1. Location in patent: Page/Page column 89
[2] Patent: WO2015/95767, 2015, A1. Location in patent: Page/Page column 104

2-Methyl-4-trifluoromethylimidazole Preparation Products And Raw materials

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 4000 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29734 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Henan Alfa Chemical Co., Ltd
+8615838112936 alfa10@alfachem.cn China 12931 58

View Lastest Price from 2-Methyl-4-trifluoromethylimidazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methyl-4-trifluoromethylimidazole pictures 2024-08-14 2-Methyl-4-trifluoromethylimidazole
33468-67-6
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
2-Methyl-4-trifluoromethylimidazole pictures 2020-01-10 2-Methyl-4-trifluoromethylimidazole
33468-67-6
US $1.00 / KG 1KG 98% HPLC 10 tons/month Career Henan Chemical Co
2-methyl-4-(trifluoromethyl)-1H-imidazole 2-METHYL-4-TRIFLUOROMETHYLIMIDAZOLE 2-Methyl-4-(trifluoroMethyl)-2H-iMidazole 2-Methyl-5-(trifluoromethyl)-1H-imidazole 2-Methyl-5-(trifluoromethyl)-1H-imidazole 95% 1H-Imidazole, 2-methyl-5-(trifluoromethyl)- 1H-Imidazole, 2-methyl-4-(trifluoromethyl)- 2-Methyl-4-trifluoromethyl-1H-imidazole 33468-67-6 Heterocycle HEH