ChemicalBook >> CAS DataBase List >>Atorvastatin tert-Butyl Ester
Atorvastatin tert-Butyl Ester
- CAS No.
- 134395-00-9
- Chemical Name:
- Atorvastatin tert-Butyl Ester
- Synonyms
- Atorvastatin t-butyl ester;(3R,5R);Atorvastatin 1;Atorvastatin calcium-8;Atorvastatin Impurity 21;Atorvastatin EP Impurity N;ATV imp N ( tertbutyl ester);Atorvastatin tert-Butyl Ester;Atorvastatin Calcium Impurity N;Atorvastatin calcium impurity 15
- CBNumber:
- CB21176137
- Molecular Formula:
- C37H43FN2O5
- Molecular Weight:
- 614.75
- MDL Number:
- MFCD09839952
- MOL File:
- 134395-00-9.mol
Last updated:2026-01-13 11:13:55
| Product description | Number | Pack Size | Price |
| (βR,δR)-Atorvastatintert-ButylEster(>90%) | A791740 | 10mg | $105 |
| (βR,δR)-Atorvastatintert-ButylEster(>90%) | A791740 | 100mg | $715 |
| ATORVASTATIN TERT-BUTYL ESTER 95.00% | API0026619 | 1MG | $721.88 |
| Atorvastatintert-butylester | 6189AA | 5g | $321 |
| Atorvastatintert-butylester | 6189AA | 10g | $554 |
| More product size | |||
| Melting point | 66-68°C |
|---|---|
| Boiling point | 721.0±60.0 °C(Predicted) |
| Density | 1.16 |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | 13.57±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| PH | 6.22 at 25℃ and 10mg/L |
| Major Application | pharmaceutical small molecule |
| InChIKey | GCPKKGVOCBYRML-LOYHVIPDSA-N |
| SMILES | Fc1ccc(cc1)c2[n](c(c(c2c4ccccc4)C(=O)Nc3ccccc3)C(C)C)CC[C@@H](O)C[C@@H](O)CC(=O)OC(C)(C)C |
| CAS DataBase Reference | 134395-00-9 |
| UNSPSC Code | 12352200 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H413 |
| Precautionary statements | P260-P273-P314-P391-P501 |
| target organs | Liver |
| WGK Germany | WGK 2 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 2 STOT RE 2 |
Atorvastatin tert-Butyl Ester price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A791740 | (βR,δR)-Atorvastatintert-ButylEster(>90%) | 134395-00-9 | 10mg | $105 | 2021-12-16 | Buy |
| TRC | A791740 | (βR,δR)-Atorvastatintert-ButylEster(>90%) | 134395-00-9 | 100mg | $715 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0026619 | ATORVASTATIN TERT-BUTYL ESTER 95.00% | 134395-00-9 | 1MG | $721.88 | 2021-12-16 | Buy |
| AK Scientific | 6189AA | Atorvastatintert-butylester | 134395-00-9 | 5g | $321 | 2021-12-16 | Buy |
| AK Scientific | 6189AA | Atorvastatintert-butylester | 134395-00-9 | 10g | $554 | 2021-12-16 | Buy |
Atorvastatin tert-Butyl Ester Chemical Properties,Uses,Production
Chemical Properties
Off-white to pale yellow solid
Uses
An impurity arising in the synthesis of Atorvastatin
Synthesis
Firstly, 90mL of methanol and compound L1 were put into a 250mL three-necked bottle. 10g into a 250mL three-necked bottle, slowly add 15% hydrochloric acid solution dropwise, the reaction at 35 for 2h, TLC to monitor the raw material reaction is complete, add saturated NaHCO solution to adjust the pH value of the reaction system to 7; pumping filtration, and 25mL 2 distilled water to wash the filter cake, at 60 blast drying; atorvastatin tert-butyl ester crude product obtained and 30mL The crude atorvastatin tert-butyl ester and 30 mL of tetrahydrofuran were added to a 50 mL single-necked flask and refluxed for 30 min, crystals were frozen and precipitated, extracted and filtered, washed with 5 mL of frozen tetrahydrofuran, and dried at 60 under a blast wind, and the product was weighed as 9.33 g, with a yield of 93.3% and a purity of 99.9%.
Atorvastatin tert-Butyl Ester Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 165)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14343 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15081 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
View Lastest Price from Atorvastatin tert-Butyl Ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-05 | Atorvastatin tert-Butyl Ester
134395-00-9
|
US $1.80-3.60 / KG | 1KG | 99% | 88KG | Career Henan Chemical Co |
-
- Atorvastatin tert-Butyl Ester
134395-00-9
- US $1.80-3.60 / KG
- 99%
- Career Henan Chemical Co
134395-00-9(Atorvastatin tert-Butyl Ester)Related Search:
Atorvastatin IMpurity 8
(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester
Atorvastatin lactone
Atorvastatin IMpurity 3
Atorvastatin Impurity 16
3S, 5S enantioMer of Atorvastatin CalciuM
Atorvastatin IMpurity 6
Atorvastatin Related Compound A
Dihydroxy Diketo Atorvastatin IMpurity
Atorvastatin Impurity 15
3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt
O-Methyl Atorvastatin Calcium Salt
Difluoro Atorvastatin Acetonide tert-Butyl Ester
Atorvastatin Epoxy Tetrahydrofuran IMpurity
Defluoro Atorvastatin intermediate 1
1of4
(4R-cis)-1,1-diMethylethyl-6-[2-[2-(4-fluorophenyl)-5-(1-isopropyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrro-1-yl]ethyl]-2,2-diMethyl-1,3-dihydroxy-4-acetate
Atorvastatin t-butyl ester
(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid tert-butyl ester
(R,dR)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole
(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)
(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbaMoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
Atorvastatin Impurity O reference substance
tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
Atorvastatin Impurity 3（Atorvastatin EP Impurity N）
tert-butyl(3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- (phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
Atorvastatin 3-Fluoro t-Butyl Ester
Atorvastatin impurity 11/Atorvastatin tert-Butyl Ester/(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
Atorvastatin calcium-8
(3R,5R)-tert-butyl 7-(2-(4-fluorophenyl)
Atorvastatin tert-Butyl Ester
(Atorvastatin Impurity 3)
Atorvastatin EP Impurity N
Atorvastatin Calcium Hydrate impurity O
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-, 1,1-diMethylethyl ester, (βR,δR)-
Atorvastatin 1
(3R,5R)
-tert-Butyl 7-(2-(4-fluorophenyl)
(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-
7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5- dihydroxy-heptanoic Acid tert-Butyl Ester
Atorvastatin tert-Butyl Ester
(R,dR)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester
Atorvastatin Impurity 21
(βR,δR)-Atorvastatin tert-Butyl Ester (>
(βR,δR)-Atorvastatin tert-Butyl Ester
(βR,δR)-Atorvastatin tert-Butyl Ester (>90%)
Atorvastatin Acid tert-Butyl Ester
Atorvastatin Acid t-Butyl EsterQ: What is
Atorvastatin Acid t-Butyl Ester Q: What is the CAS Number of
Atorvastatin Acid t-Butyl Ester Q: What is the storage condition of
Atorvastatin Acid t-Butyl Ester Q: What are the applications of
Atorvastatin Acid t-Butyl Ester
ATV imp N ( tertbutyl ester)
Atorvastatin Calcium Impurity N
Atorvastatin Calcium EP Impurity N
Atorvastatin calcium impurity 15
Atorvastatin Impurity 3 (Atorvastatin tert-Butyl Ester)
(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester
Atorvastatin Acid t-Butyl Ester
(3R,5R)-7-[3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2isopropyl-4- phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid t-butyl ester
Atorvastatin EP Impurity-N (t-Butyl ester)
Atorvastatin EP Impurity N (Atorvastatin tert-Butyl Ester)
(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate (Atorvastatin calcium Impurity)
(bR,deltaR)-Atorvastatin tert-Butyl Ester (>90%)
Atorvastatin Calcium Impurity O Reference Standard
134395-00-9
C37H43FN2O5
Atorvastatin intermediates
Pfizer compounds
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Intermediates & Fine Chemicals
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