4-Chloro-2-methoxyphenylboronic acid
- CAS No.
- 762287-57-0
- Chemical Name:
- 4-Chloro-2-methoxyphenylboronic acid
- Synonyms
- 2-Borono-5-chloroanisole;4-Chloro-2-methoxyphenylboronic;oro-2-methoxybenzeneboronic acid;4-chloro-2-Methoxybenzaldehyde acid;4-Chloro-2-methoxybenzeneboronicaci;4-Chloro-2-methoxyphenylboronic aci;4-CHLORO-2-METHOXYPHENYLBORONIC ACID;2-Methoxy-4-chlorobenzeneboronic acid;4-CHLORO-2-METHOXYBENZENEBORONIC ACID;B-(4-Chloro-2-methoxyphenyl)boronic acid
- CBNumber:
- CB2120832
- Molecular Formula:
- C7H8BClO3
- Molecular Weight:
- 186.4
- MDL Number:
- MFCD02684317
- MOL File:
- 762287-57-0.mol
| Product description | Number | Pack Size | Price |
| 4-Chloro-2-methoxyphenylboronic Acid (contains varying amounts of Anhydride) | C3248 | 1g | $183 |
| 4-Chloro-2-methoxyphenylboronic Acid (contains varying amounts of Anhydride) | C3248 | 200mg | $60 |
| 4-Chloro-2-methoxyphenylboronicAcid | C596833 | 50mg | $60 |
| (4-Chloro-2-methoxyphenyl)boronicacid 97% | C2214 | 25g | $570 |
| (4-Chloro-2-methoxyphenyl)boronicacid >97% | 126621 | 25g | $935 |
| More product size | |||
| Melting point | 128-134°C |
|---|---|
| Boiling point | 345.4±52.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 8.42±0.58(Predicted) |
| color | White to Almost white |
| InChI | InChI=1S/C7H8BClO3/c1-12-7-4-5(9)2-3-6(7)8(10)11/h2-4,10-11H,1H3 |
| InChIKey | NZRRMTBNTSBIFH-UHFFFAOYSA-N |
| SMILES | B(C1=CC=C(Cl)C=C1OC)(O)O |
| CAS DataBase Reference | 762287-57-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
4-Chloro-2-methoxyphenylboronic acid price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C3248 | 4-Chloro-2-methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 762287-57-0 | 1g | $183 | 2025-07-31 | Buy |
| TCI Chemical | C3248 | 4-Chloro-2-methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 762287-57-0 | 200mg | $60 | 2025-07-31 | Buy |
| TRC | C596833 | 4-Chloro-2-methoxyphenylboronicAcid | 762287-57-0 | 50mg | $60 | 2021-12-16 | Buy |
| Synthonix | C2214 | (4-Chloro-2-methoxyphenyl)boronicacid 97% | 762287-57-0 | 25g | $570 | 2021-12-16 | Buy |
| Matrix Scientific | 126621 | (4-Chloro-2-methoxyphenyl)boronicacid >97% | 762287-57-0 | 25g | $935 | 2021-12-16 | Buy |
4-Chloro-2-methoxyphenylboronic acid Chemical Properties,Uses,Production
Uses
suzuki reaction
Synthesis
174913-09-8
121-43-7
762287-57-0
General procedure for the synthesis of 4-chloro-2-methoxyphenylboronic acid: preparation of intermediate I-1. 22.1 g (100 mmol) of 2-bromo-5-chloroanisole was dissolved in 500 mL of tetrahydrofuran (THF) and stirred for 10 min at -78 °C and protected by nitrogen (N2). Subsequently, 44 mL of a 2.5 M solution of n-butyllithium (n-BuLi) was slowly added through a dropping funnel and stirring was continued for 30 minutes. Next, 10.4 g (110 mmol) of trimethyl borate was slowly added dropwise, and after completion of the dropwise addition, the reaction mixture was warmed to room temperature and stirred for 3 hours. After completion of the reaction, the reaction was quenched with 300 mL of 1 M hydrochloric acid (HCl) and the organic layer was extracted three times with diethyl ether and washed with water. The organic layers were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography to afford 13.61 g of Intermediate I-1 (73 mmol, 73% yield). The resulting compound was characterized by mass spectrometry (MS/FAB): theoretical value of [M+H]+ (C7H8BClO3) 186.40, measured value 186.47.
References
[1] Organic Letters, 2016, vol. 18, # 15, p. 3630 - 3633
[2] Patent: US2016/190448, 2016, A1. Location in patent: Paragraph 0261; 0262; 0263
[3] Patent: US2016/190449, 2016, A1. Location in patent: Paragraph 0271; 0272
4-Chloro-2-methoxyphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13799 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 4-Chloro-2-methoxyphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 4-Chloro-2-methoxyphenylboronic acid
762287-57-0
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-04-04 | 4-Chloro-2-methoxyphenylboronic acid
762287-57-0
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2020-06-02 | 4-Chloro-2-methoxyphenylboronic acid 762287-57-0
762287-57-0
|
US $66.00 / KG | 1KG | 99.50% IN STOCK | 20 MT per month | Chemwill Asia Co.,Ltd. |
-
- 4-Chloro-2-methoxyphenylboronic acid
762287-57-0
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 4-Chloro-2-methoxyphenylboronic acid
762287-57-0
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 4-Chloro-2-methoxyphenylboronic acid 762287-57-0
762287-57-0
- US $66.00 / KG
- 99.50% IN STOCK
- Chemwill Asia Co.,Ltd.
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