ChemicalBook >> CAS DataBase List >>4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone

4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone

CAS No.
886599-05-9
Chemical Name:
4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone
Synonyms
GW814408X;4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone
CBNumber:
CB212224663
Molecular Formula:
C19H16N6O
Molecular Weight:
344.37
MDL Number:
MOL File:
886599-05-9.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:46

4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Properties

Boiling point 616.4±55.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
pka 6.00±0.70(Predicted)

4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Chemical Properties, Uses, Production

Uses

GW814408X is a kinase chemical genome group (KCGS) compound that inhibits the AURKC kinase involved in cell cycle progression, checkpoint regulation, and cell division. GW814408X exhibits cell line-dependent toxicity, e.g., cytotoxic effects on HeLa cells. GW814408X acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1].

References

[1] Wells CI, et al. The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. Int J Mol Sci. 2021 Jan 8;22(2):566. DOI:10.3390/ijms22020566
[2] Dranchak P, et al. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. PLoS One. 2013;8(3):e57888. DOI:10.1371/journal.pone.0057888

4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Preparation Products And Raw materials

Raw materials

Preparation Products

4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9699 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 ivan@atkchemical.com China 32997 60
4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone GW814408X 886599-05-9