4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone
- CAS No.
- 886599-05-9
- Chemical Name:
- 4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone
- Synonyms
- GW814408X;4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone
- CBNumber:
- CB212224663
- Molecular Formula:
- C19H16N6O
- Molecular Weight:
- 344.37
- MDL Number:
- MOL File:
- 886599-05-9.mol
- MSDS File:
- SDS
4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Chemical Properties, Uses, Production
Uses
GW814408X is a kinase chemical genome group (KCGS) compound that inhibits the AURKC kinase involved in cell cycle progression, checkpoint regulation, and cell division. GW814408X exhibits cell line-dependent toxicity, e.g., cytotoxic effects on HeLa cells. GW814408X acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1].
References
[1] Wells CI, et al. The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. Int J Mol Sci. 2021 Jan 8;22(2):566. DOI:10.3390/ijms22020566
[2] Dranchak P, et al. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. PLoS One. 2013;8(3):e57888. DOI:10.1371/journal.pone.0057888
4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Preparation Products And Raw materials
Raw materials
Preparation Products
4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 13301690235 | Sales@ATKchemical.com | China | 9699 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Supplier | Advantage |
|---|---|
| Shanghai Chaolan Chemical Technology Center | 58 |
| TargetMol Chemicals Inc. | 58 |
| ATK CHEMICAL COMPANY LIMITED | 60 |




