ChemicalBook >> CAS DataBase List >>5,10-Methylene-THF

5,10-Methylene-THF

CAS No.
31690-11-6
Chemical Name:
5,10-Methylene-THF
Synonyms
5,10-Methylene-THF;Folinic Acid Impurity 7;Folic Acid EP Impurity I;Levofolinate EP Impurity I;Folinic Acid EP Impurity I;(S)-2-(4-((R)-3-amino-1-oxo;Calcium Levofolinate EP Impurity I;(6R) 5,10-Methylenetetrahydrofolate;(6aR)-5,10-Methylenetetrahydrofolic Acid;N5,N10-Methylene-5,6,7,8-tetrahydrofolate
CBNumber:
CB21235571
Molecular Formula:
C20H23N7O6
Molecular Weight:
457.44
MDL Number:
MOL File:
31690-11-6.mol
Last updated:2025-08-21 22:16:43

5,10-Methylene-THF Properties

Density 1.75±0.1 g/cm3(Predicted)
pka 3.47±0.10(Predicted)
InChIKey QYNUQALWYRSVHF-OLZOCXBDSA-N
SMILES C(O)(=O)[C@H](CCC(O)=O)NC(=O)C1=CC=C(N2C[C@@]3([H])CNC4=C(N3C2)C(=O)NC(N)=N4)C=C1
FDA UNII Z8R4A37V9Q

5,10-Methylene-THF Chemical Properties,Uses,Production

Uses

Arfolitixorin is a folate prodrug that is used in the treatment for colorectal cancer as a way for increase in efficacy and reducing the side effects of antimetabolites used in cancer treatment.

Definition

ChEBI: (6R)-5,10-methylenetetrahydrofolic acid is the (6R)-stereoisomer of 5,10-methylenetetrahydrofolic acid. It has a role as an Escherichia coli metabolite, a mouse metabolite and a cofactor. It is a conjugate acid of a (6R)-5,10-methylenetetrahydrofolate(2-).

5,10-Methylene-THF Preparation Products And Raw materials

Raw materials

Preparation Products

5,10-Methylene-THF Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32434 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11922 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 19961 58
QUALITY CONTROL SOLUTIONS LTD.
+86-0755-66853366 +86-13670046396 export03@qcsrm.com China 24342 58
Nanjing zehe Pharmaceutical Technology Co., Ltd 17768115366 henry124604479@163.com China 228 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 18234 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9906 50
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 9662 55
TOSUN PHARM 020-61855200 13326451905 260366801@qq.com China 7906 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 020-36607679 17825480238 3008233717@qq.com China 9879 12

View Lastest Price from 5,10-Methylene-THF manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Arfolitixorin pictures 2025-08-21 Arfolitixorin
31690-11-6
US $2500.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • Arfolitixorin pictures
  • Arfolitixorin
    31690-11-6
  • US $2500.00-1980.00 / mg
  • TargetMol Chemicals Inc.
5,10-Methylene-THF (6R) 5,10-Methylenetetrahydrofolate 5,10-Methylene-THF// (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydro imidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzami do)pentanedioic acid N5,N10-Methylene-5,6,7,8-tetrahydrofolate (S)-2-(4-((R)-3-amino-1-oxo (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydroimidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzamido)pentanedioic acid L-Glutamic acid, N-[4-[(6aR)-3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl]- Folinic Acid EP Impurity I Folinic Acid Impurity 7 Calcium Levofolinate EP Impurity I Levofolinate EP Impurity I (6aR)-5,10-Methylenetetrahydrofolic Acid Folic Acid EP Impurity I Calcium Levofolinate Impurity 10 (Calcium Levofolinate EP Impurity I) Levofolinate EP Impurity I(Folic Acid EP Impurity I) 31690-11-6 C20H23N7O6