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Azlocillin sodium

CAS No.
37091-65-9
Chemical Name:
Azlocillin sodium
Synonyms
AZLOCILLIN SODIUM SALT;securopen;Prestwick_48;sodium azlocillin;AZLOCILLIN SODIUM;AZLOCILLINE SODIUM;Aloxicillin sodium;monosodiumazlocillin;D-alpha-([Imidazolidin;Azlocillin sodium, >=95%
CBNumber:
CB2128131
Molecular Formula:
C20H22N5NaO6S
Molecular Weight:
483.47
MDL Number:
MFCD07793330
MOL File:
37091-65-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-03 11:24:09
Product description Number Pack Size Price
Azlocillin sodium salt A7926 1g $153
Azlocillin sodium salt A7926 5g $521
Azlocillin (sodium salt) ≥95% 18424 250mg $36
Azlocillin (sodium salt) ≥95% 18424 500mg $53
Azlocillin (sodium salt) ≥95% 18424 1g $96
More product size

Azlocillin sodium Properties

Melting point >199oC (dec.)
Flash point >110°(230°F)
storage temp. Inert atmosphere,2-8°C
solubility H2O: soluble50mg/mL
form powder
color White to Off-White
Water Solubility Freely soluble in water
Stability Hygroscopic
InChIKey UVOCNBWUHNCKJM-CHNWLKQKNA-M
SMILES N12C([C@@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)C3=CC=CC=C3)[C@H]1SC(C)(C)[C@@H]2C([O-])=O)=O.[Na+] |&1:2,6,22,27,r|
CAS DataBase Reference 37091-65-9(CAS DataBase Reference)
FDA UNII DWV1EFW947
UNSPSC Code 51282412
NACRES NA.85

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H317-H334
Precautionary statements  P280-P302+P352
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  42/43
Safety Statements  36
WGK Germany  3
RTECS  XH9250000
Storage Class 13 - Non Combustible Solids
Hazard Classifications Resp. Sens. 1
Skin Sens. 1
Toxicity mouse,LD50,intramuscular,15420mg/kg (15420mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: TREMORBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX),Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and Medical Biotechnology. Vol. 32, Pg. 453, 1987.

Azlocillin sodium price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A7926 Azlocillin sodium salt 37091-65-9 1g $153 2025-07-31 Buy
Sigma-Aldrich A7926 Azlocillin sodium salt 37091-65-9 5g $521 2023-06-20 Buy
Cayman Chemical 18424 Azlocillin (sodium salt) ≥95% 37091-65-9 250mg $36 2026-04-30 Buy
Cayman Chemical 18424 Azlocillin (sodium salt) ≥95% 37091-65-9 500mg $53 2026-04-30 Buy
Cayman Chemical 18424 Azlocillin (sodium salt) ≥95% 37091-65-9 1g $96 2026-04-30 Buy
Product number Packaging Price Buy
A7926 1g $153 Buy
A7926 5g $521 Buy
18424 250mg $36 Buy
18424 500mg $53 Buy
18424 1g $96 Buy

Azlocillin sodium Chemical Properties,Uses,Production

Originator

Securopen,Bayer,W. Germany,1977

Uses

Antibacterial;Bacterial transpeptidase inhibitor

Uses

Azlocillin sodium is a semisynthetic penicillin and is a potent 1-lactam antibiotic. It is often used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques.

Definition

ChEBI: Azlocillin sodium is an organic sodium salt. It contains an azlocillin(1-).

Manufacturing Process

3.8 parts by weight of D-(-)-α-[(imidazolidin-2-on-1-yl)carbonylamino]phenylacetic acid were dissolved in 65 parts by volume of dichloromethane. 2.7 parts by weight of 1-methyl-2-chloro-δ1-pyrrolinium chloride were added, and after cooling to -10°C 2.0 parts by volume of triethylamine were added gradually. This reaction mixture was then stirred for one hour at -5°C (mixture A). 4.0 parts by weight of 6-aminopenicillanic acid in 80 parts by volume of dichloromethane were treated with 4.4 parts by volume of triethylamine and 4.0 parts by weight of anhydrous sodium sulfate and then stirred for two hours at room temperature. After filtration, the solution was cooled to -20°C and combined with the mixture A. The reaction mixture was left to reach 0°C of its own accord, and was then stirred for a further hour at 0°C. The solvent was removed in a rotary evaporator, the residue was dissolved in water, and the solution was covered with a layer of ethyl acetate and acidified with dilute hydrochloric acid at 0° to 5°C, while stirring, until pH 1.5 was reached. The organic phase was then separated off, washed with water, dried over magnesium sulfate while cooling, and filtered, and after dilution with an equal amount of ether the sodium salt of the penicillin was precipitated from the filtrate by adding a solution of sodium 2-ethylcaproate dissolved in ether containing methanol. Yield: 1.3 parts by weight.

brand name

Azlin (Bayer).

Therapeutic Function

Antibacterial

37091-66-0
37091-65-9
Synthesis of Azlocillin sodium from Azlocillin

Azlocillin sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Azlocillin sodium manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Azlocillin sodium salt pictures 2026-06-02 Azlocillin sodium salt
37091-65-9
$29.00 98.30% 10g TargetMol Chemicals Inc.
Azlocillin sodium salt pictures 2026-06-02 Azlocillin sodium salt
37091-65-9
$29.00 98.30% 10g TargetMol Chemicals Inc.
Azlocillin sodium salt pictures 2026-06-02 Azlocillin sodium salt
37091-65-9
$29.00 98.30% 10g TargetMol Chemicals Inc.

Azlocillin sodium Spectrum

sodium [2S-[2alpha,5alpha,6beta(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Sterile Azlocillin sodium AZLOCILLINE SODIUM d-α-([imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin sodium azlocillin sodium [2s-[2a,5a,6b(s*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-,monosodiumsalt,( 5-alpha,6-beta(s*)))-2s-(2-alph monosodiumazlocillin securopen sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2S)-1-oxo-2-[[oxo-(2-oxo-1-imidazolidinyl)methyl]amino]-2-phenylethyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (2S,5β)-3,3-Dimethyl-7-oxo-6α-[[(R)-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid sodium salt D-alpha-([Imidazolidin Prestwick_48 Azlocillin sodium salt,D-α-([Imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin Azlocillin Sodium (200 mg) 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, sodium salt (1:1), (2S,5R,6R)- Azlocillin sodium, >=95% Sodium [2S-[2a,5a,6b(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxy D-ALPHA-[(IMIDAZOLIDIN-2-ON-1-YL)-CARBONYLAMINO]BENZYLPENICILLIN D-A-([IMIDAZOLIDIN-2-ON-1-YL]CARBONYLAMINO)BENZYLPENICILLIN AZLOCILLIN SODIUM 3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-((R)-2-(2-oxoimidazolidine-1-carboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Azlocillin sodium USP/EP/BP Azlocillin Sodium Salt (1.0mg/ml in DMSO) AzlocillinSodiumQ: What is AzlocillinSodium Q: What is the CAS Number of AzlocillinSodium Q: What is the storage condition of AzlocillinSodium Q: What are the applications of AzlocillinSodium Aloxicillin sodium Phenylephrine Impurity 105-d3 Azlocillin sodium salt, 10 mM in DMSO Azlocillin sodium salt (Standard) AZLOCILLIN SODIUM SALT 37091-65-9 C20H22N5NaO6S C20H23N5O6SNa C20H22N5O6SNa Antibiotics A-F Antibiotics A to Z Antibiotics BioChemical Active Pharmaceutical Ingredients Miscellaneous 37091-65-9