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Azlocillin sodium

Azlocillin sodium structure

CAS No.: 37091-65-9

Chemical Name:: Azlocillin sodium

Synonyms: AZLOCILLIN SODIUM SALT;securopen;Prestwick_48;sodium azlocillin;AZLOCILLIN SODIUM;AZLOCILLINE SODIUM;Aloxicillin sodium;monosodiumazlocillin;D-alpha-([Imidazolidin;Azlocillin sodium, >=95%

CBNumber:: CB2128131

Molecular Formula:: C20H22N5NaO6S

Molecular Weight:: 483.47

MDL Number:: MFCD07793330

MOL File:: 37091-65-9.mol

Last updated:2025-04-30 15:13:52

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Azlocillin sodium Properties

Melting point	>199oC (dec.)
Flash point	>110°(230°F)
storage temp.	Inert atmosphere,2-8°C
solubility	H2O: soluble50mg/mL
form	powder
color	White to Off-White
Water Solubility	Freely soluble in water
Stability	Hygroscopic
CAS DataBase Reference	37091-65-9(CAS DataBase Reference)
FDA UNII	DWV1EFW947

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H317-H334
Precautionary statements	P280-P302+P352
Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	36
WGK Germany	3
RTECS	XH9250000
Toxicity	mouse,LD50,intramuscular,15420mg/kg (15420mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: TREMORBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX),Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and Medical Biotechnology. Vol. 32, Pg. 453, 1987.

Azlocillin sodium price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A7926	Azlocillin sodium salt	37091-65-9	1g	$149	2024-03-01	Buy
Sigma-Aldrich	A7926	Azlocillin sodium salt	37091-65-9	5g	$521	2023-06-20	Buy
Alfa Aesar	J66895	Azlocillin sodium, 90%	37091-65-9	10g	$343	2021-12-16	Buy
Alfa Aesar	J66895	Azlocillin sodium, 90%	37091-65-9	1g	$37.1	2021-12-16	Buy
Cayman Chemical	18424	Azlocillin (sodium salt) ≥95%	37091-65-9	250mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
A7926	1g	$149	Buy
A7926	5g	$521	Buy
J66895	10g	$343	Buy
J66895	1g	$37.1	Buy
18424	250mg	$32	Buy

Azlocillin sodium Chemical Properties,Uses,Production

Originator

Securopen,Bayer,W. Germany,1977

Uses

Antibacterial;Bacterial transpeptidase inhibitor

Uses

Azlocillin sodium is a semisynthetic penicillin and is a potent 1-lactam antibiotic. It is often used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques.

Definition

ChEBI: Azlocillin sodium is an organic sodium salt. It contains an azlocillin(1-).

Manufacturing Process

3.8 parts by weight of D-(-)-α-[(imidazolidin-2-on-1-yl)carbonylamino]phenylacetic acid were dissolved in 65 parts by volume of dichloromethane. 2.7 parts by weight of 1-methyl-2-chloro-δ1-pyrrolinium chloride were added, and after cooling to -10°C 2.0 parts by volume of triethylamine were added gradually. This reaction mixture was then stirred for one hour at -5°C (mixture A). 4.0 parts by weight of 6-aminopenicillanic acid in 80 parts by volume of dichloromethane were treated with 4.4 parts by volume of triethylamine and 4.0 parts by weight of anhydrous sodium sulfate and then stirred for two hours at room temperature. After filtration, the solution was cooled to -20°C and combined with the mixture A. The reaction mixture was left to reach 0°C of its own accord, and was then stirred for a further hour at 0°C. The solvent was removed in a rotary evaporator, the residue was dissolved in water, and the solution was covered with a layer of ethyl acetate and acidified with dilute hydrochloric acid at 0° to 5°C, while stirring, until pH 1.5 was reached. The organic phase was then separated off, washed with water, dried over magnesium sulfate while cooling, and filtered, and after dilution with an equal amount of ether the sodium salt of the penicillin was precipitated from the filtrate by adding a solution of sodium 2-ethylcaproate dissolved in ether containing methanol. Yield: 1.3 parts by weight.

brand name

Azlin (Bayer).

Therapeutic Function

Antibacterial

Azlocillin sodium synthesis

Synthesis of Azlocillin sodium from Azlocillin

Azlocillin sodium Preparation Products And Raw materials

Raw materials

6-Aminopenicillanic acid Azlocillin

Preparation Products

Azlocillin sodium Suppliers

Global( 284)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+86-15531157085; +8615531157085	abby@chuanghaibio.com	China	8807	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12788	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	1015	58
Hangzhou Hyper Chemicals Limited	+86-0086-57187702781 +8613675893055	info@hyper-chem.com	China	295	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29856	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6383	58
HubeiwidelychemicaltechnologyCo.,Ltd	18627774460	faith@widelychemical.com	CHINA	742	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hangzhou ICH Biofarm Co., Ltd	58
Hangzhou Hyper Chemicals Limited	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
HubeiwidelychemicaltechnologyCo.,Ltd	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from Azlocillin sodium manufacturers

Update time	Product	Price	Purity	Supply Ability	Manufacturer
2025-04-30	Azlocillin sodium salt 37091-65-9	US $30.00-48.00 / mg	97.63%	10g	TargetMol Chemicals Inc.
2025-04-30	Azlocillin sodium salt 37091-65-9	US $30.00-48.00 / mg	97.63%	10g	TargetMol Chemicals Inc.
2025-04-28	Azlocillin sodium salt 37091-65-9	US $30.00-48.00 / mg	97.63%	10g	TargetMol Chemicals Inc.

Azlocillin sodium salt
37091-65-9
US $30.00-48.00 / mg
97.63%
TargetMol Chemicals Inc.

Azlocillin sodium salt
37091-65-9
US $30.00-48.00 / mg
97.63%
TargetMol Chemicals Inc.

Azlocillin sodium salt
37091-65-9
US $30.00-48.00 / mg
97.63%
TargetMol Chemicals Inc.

Azlocillin sodium Spectrum

Azlocillin sodium(37091-65-9)¹HNMR

37091-65-9(Azlocillin sodium)Related Search:

Sodium gluconate Diclofenac sodium Acetylacetone Dimethyl ether Diethylstilbestrol

Dimethyl sulfide Dimethyl fumarate Azlocillin N-ACETYL-L-TYROSINE ETHYL ESTER Sodium formate

Sodium bicarbonate N,N-Dimethylformamide Acetylferrocene Sodium carbonate Ampicillin sodium

Ampicillin Dimethyl phthalate Penicillin G

1of4

sodium [2S-[2alpha,5alpha,6beta(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Sterile Azlocillin sodium AZLOCILLINE SODIUM d-α-([imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin sodium azlocillin sodium [2s-[2a,5a,6b(s*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-,monosodiumsalt,( 5-alpha,6-beta(s*)))-2s-(2-alph monosodiumazlocillin securopen sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2S)-1-oxo-2-[[oxo-(2-oxo-1-imidazolidinyl)methyl]amino]-2-phenylethyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (2S,5β)-3,3-Dimethyl-7-oxo-6α-[[(R)-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid sodium salt D-alpha-([Imidazolidin Prestwick_48 Azlocillin sodium salt,D-α-([Imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin Azlocillin Sodium (200 mg) 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, sodium salt (1:1), (2S,5R,6R)- Azlocillin sodium, >=95% Sodium [2S-[2a,5a,6b(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxy D-ALPHA-[(IMIDAZOLIDIN-2-ON-1-YL)-CARBONYLAMINO]BENZYLPENICILLIN D-A-([IMIDAZOLIDIN-2-ON-1-YL]CARBONYLAMINO)BENZYLPENICILLIN AZLOCILLIN SODIUM AZLOCILLIN SODIUM SALT 3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-((R)-2-(2-oxoimidazolidine-1-carboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Azlocillin sodium USP/EP/BP Azlocillin Sodium Salt (1.0mg/ml in DMSO) AzlocillinSodiumQ: What is AzlocillinSodium Q: What is the CAS Number of AzlocillinSodium Q: What is the storage condition of AzlocillinSodium Q: What are the applications of AzlocillinSodium Phenylephrine Impurity 105-d3 Aloxicillin sodium Azlocillin sodium salt, 10 mM in DMSO 37091-65-9 C20H22N5NaO6S C20H23N5O6SNa C20H22N5O6SNa Antibiotics A-F Antibiotics A to Z Antibiotics BioChemical Active Pharmaceutical Ingredients Miscellaneous 37091-65-9