6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
- CAS No.
- 26893-73-2
- Chemical Name:
- 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
- Synonyms
- 1-Naphthalene bromide;6-METHOXYPICOLINIC ACID;Picolinic acid, 6-methoxy-;2-methoxy-6-picolinic acid;6-Methoxypyridine-2-carboxyL;6-methoxypyridine-2-carboxylicaci;6-Methoxypyridin-2-carboxylic acid;6-METHOXYPYRIDINE-2-CARBOXYLIC ACID;6-METHOXY-2-PYRIDINECARBOXYLIC ACID;2-methoxypyridine-6-carboxylic acid
- CBNumber:
- CB2128292
- Molecular Formula:
- C7H7NO3
- Molecular Weight:
- 153.14
- MDL Number:
- MFCD06800962
- MOL File:
- 26893-73-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Methoxypyridine-2-carboxylic acid 97% | 679607 | 1g | $70.9 |
| 6-Methoxypyridine-2-carboxylic Acid >98.0%(GC)(T) | M2189 | 1g | $43 |
| 6-Methoxypyridine-2-carboxylic Acid >98.0%(GC)(T) | M2189 | 5g | $173 |
| 6-Methoxypicolinicacid | M266460 | 500mg | $65 |
| 6-METHOXY-PYRIDINE-2-CARBOXYLIC ACID 95.00% | CHM0027806 | 5G | $2181.31 |
| More product size | |||
| Melting point | 38.5-39.5°C |
|---|---|
| Boiling point | 300.8±22.0 °C(Predicted) |
| Density | 1.284±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | powder to crystal |
| pka | 3.52±0.10(Predicted) |
| color | White to Almost white |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C7H7NO3/c1-11-6-4-2-3-5(8-6)7(9)10/h2-4H,1H3,(H,9,10) |
| InChIKey | QCCJUEURAZMEGY-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=NC(OC)=CC=C1 |
| CAS DataBase Reference | 26893-73-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
6-METHOXYPYRIDINE-2-CARBOXYLIC ACID price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 679607 | 6-Methoxypyridine-2-carboxylic acid 97% | 26893-73-2 | 1g | $70.9 | 2023-06-20 | Buy |
| TCI Chemical | M2189 | 6-Methoxypyridine-2-carboxylic Acid >98.0%(GC)(T) | 26893-73-2 | 1g | $43 | 2026-03-19 | Buy |
| TCI Chemical | M2189 | 6-Methoxypyridine-2-carboxylic Acid >98.0%(GC)(T) | 26893-73-2 | 5g | $173 | 2026-03-19 | Buy |
| TRC | M266460 | 6-Methoxypicolinicacid | 26893-73-2 | 500mg | $65 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0027806 | 6-METHOXY-PYRIDINE-2-CARBOXYLIC ACID 95.00% | 26893-73-2 | 5G | $2181.31 | 2021-12-16 | Buy |
6-METHOXYPYRIDINE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Synthesis
19621-92-2
74-88-4
26893-73-2
General procedure for the synthesis of 6-methoxypyridine-2-carboxylic acid from 6-hydroxypyridine-2-carboxylic acid and iodomethane: To a solution of 6-hydroxypyridine-2-carboxylic acid (1.39 g, 10.0 mmol) in toluene (35 mL) was added silver oxide (2.43 g, 10.5 mmol) and the mixture was stirred for 30 minutes. Subsequently, iodomethane (1.31 mL, 21.0 mmol) was added to the reaction system and the reaction mixture was heated to reflux and reacted overnight. Upon completion of the reaction, the reaction mixture was filtered through diatomaceous earth and the filtrate was concentrated to give 1.45 g of methyl 6-methoxypyridine-2-carboxylate as a yellow solid. The solid was dissolved in tetrahydrofuran (50 mL) and then added to a mixture of 5N NaOH (20 mL, 100 mmol) and water (5 mL). After 1 hour of reaction, the reaction mixture was acidified to pH 3 with 5N HCl and then concentrated. To the resulting white solid, 20% MeOH/CHCl3 solvent mixture was added and the mixture was sonicated for 20 min. The mixture was filtered and the mother liquor was dried with anhydrous MgSO4 and concentrated to give 1.33 g of 6-methoxypyridine-2-carboxylic acid as a white solid in 87% yield. The product was confirmed to be structurally consistent by 1H NMR and MS (ion spray) showed m/z 152 (M-).
References
[1] Patent: US2003/100576, 2003, A1
6-METHOXYPYRIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29822 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 954 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9548 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
26893-73-2
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-11-18 | 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
26893-73-2
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-09-25 | 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
26893-73-2
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
26893-73-2
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
26893-73-2
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID
26893-73-2
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
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