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1-Adamantanol

1-Adamantanol Structure
1-Adamantanol structure
CAS No.
768-95-6
Chemical Name:
1-Adamantanol
Synonyms
ADAMANTANOL;ADAMANTAN-1-OL;(3s,5s,7s)-adamantan-1-ol;1-Adamantol;1-AD-OH;1-Admantanol;1-HYDROXYADAMANTANE;1-Adamatanol;1-ADA-OH;damantol-(1)
CBNumber:
CB2135047
Molecular Formula:
C10H16O
Molecular Weight:
152.23
MDL Number:
MFCD00074729
MOL File:
768-95-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:56:01
Product description Number Pack Size Price
1-Adamantanol ReagentPlus , 99% 130346 5g $40
1-Adamantanol ReagentPlus , 99% 130346 25g $91.9
Adamantan-1-ol (99.99%, trace metals basis) min. 98.0 % A3477 1G $59
Adamantan-1-ol (99.99%, trace metals basis) min. 98.0 % A3477 5G $175
1-Adamantanol >98.0%(GC) A0939 25g $62
More product size
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1-Adamantanol Properties

Melting point 247 °C (subl.) (lit.)
Boiling point 214.73°C (rough estimate)
Density 0.8544 (rough estimate)
refractive index 1.4880 (estimate)
Flash point 240°C
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Crystalline Powder or Needles
pka 15.38±0.20(Predicted)
color White to off-white
Water Solubility Soluble in ethanol , methanol, and diethyl ether. Partly miscible in water.
Sublimation 240 ºC
BRN 1903952
Henry's Law Constant 6.0×100 mol/(m3Pa) at 25℃, Roon et al. (2005)
InChI 1S/C10H16O/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9,11H,1-6H2/t7-,8+,9-,10-
InChIKey VLLNJDMHDJRNFK-UHFFFAOYSA-N
SMILES OC12C[C@H]3C[C@H](C[C@H](C3)C1)C2
CAS DataBase Reference 768-95-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII P9J0B0C8ZB
NIST Chemistry Reference 1-Adamantanol(768-95-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
RTECS  AU4980000
Hazard Note  Irritant
HS Code  29061900
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

1-Adamantanol price More Price(70)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 130346 1-Adamantanol ReagentPlus , 99% 768-95-6 5g $40 2026-04-30 Buy
Sigma-Aldrich 130346 1-Adamantanol ReagentPlus , 99% 768-95-6 25g $91.9 2026-04-30 Buy
TCI Chemical A3477 Adamantan-1-ol (99.99%, trace metals basis) min. 98.0 % 768-95-6 1G $59 2026-04-30 Buy
TCI Chemical A3477 Adamantan-1-ol (99.99%, trace metals basis) min. 98.0 % 768-95-6 5G $175 2026-04-30 Buy
TCI Chemical A0939 1-Adamantanol >98.0%(GC) 768-95-6 25g $62 2026-04-30 Buy
Product number Packaging Price Buy
130346 5g $40 Buy
130346 25g $91.9 Buy
A3477 1G $59 Buy
A3477 5G $175 Buy
A0939 25g $62 Buy

1-Adamantanol Chemical Properties,Uses,Production

Outline

1-adamantanol is also known as 1-hydroxide adamantane, 1-tricyclo [3.3.1.1 (3.7)] decyl alcohol. At room temperature, it is white crystalline powder with the melting point higher than 240 ℃. It is soluble in organic solvents and insoluble in water with sublimation property. It can be used for the manufacture of synthetic adamantane derivatives and adapalene. It can react with vinylidene chloride to generate 1-adamantane acetic acid. 1-adamantyl acetate can further undergo bromination and hydrolyzed into 3-hydroxy-1-adamantyl acetate which can further react with vinylidene chloride to give 1, 3-adamantane di-acetic acid.
1-adamantanol can have Friedel-Crafts alkylation reaction acetanilide in the 98% sulfuric acid medium at room temperature for direct synthesis of 1, 3-bis (4-acetylamino-phenyl) adamantane which can undergo alkaline hydrolysis for synthesis of 1, 3 bis (4-aniline) adamantane. The synthetic route has many advantages including relative high reaction yield and easy purification, etc., therefore greatly facilitating the synthesis of 1, 3-diaryl adamantane derivatives.
The above information is edited by the Chemicalbook of Dai Xiongfeng.

Uses

1-adamantanol can be used as the intermediate for synthesis of adamantanes derivatives. For example, it can be used for the manufacture of synthetic adamantane derivatives and adapalene. It can react with vinylidene chloride to give 1-adamantane acetic acid.

Description

1-Adamantanol is a cyclic molecule with a hydroxyl group. It is produced by the oxidation of 2-methyl-2-adamantanol. 1-Adamantanol has been shown to be an effective substrate for bioremediation in wastewater treatment plants and can be used as a precursor to produce trifluoroacetic acid.

Chemical Properties

white to off-white crystalline powder or needles

Uses

1-Adamantanol was used in the preparation of 1,3-adamantanediol. It is used in the manufacture of synthetic adamantane derivatives and adapalene.

Synthesis Reference(s)

Synthetic Communications, 19, p. 2061, 1989 DOI: 10.1080/00397918908052598
Tetrahedron Letters, 28, p. 1941, 1987 DOI: 10.1016/S0040-4039(00)96015-5

Purification Methods

If 2-adamantanol is a suspected impurity, then dissolve the substance (10g) in acetone (100mL) and add Jones's reagent [CrO3 (10.3g) in H2O (30mL)], then conc H2SO4 (8.7mL) is added dropwise (turns green in colour) until excess reagent is present (slight red colour). Stir overnight, decant the acetone solution from the Cr salts and adamantan-2-one, dry (Na2SO4) and evaporate to dryness. The residue (ca 7g) is chromatographed through Al2O3 (250g) and washed with 50% *benzene/pet ether (b 40-60o), then 100% Et2O (to remove any adamantan-2-one present) and the 1-adamantanol is then eluted with 5% MeOH in Et2O. The eluate is evaporated, and the residue is recrystallised from pet ether (b 30-60o) at -70o, m 287.2-288.5o. It also crystallises from MeOH and can be sublimed in vacuo. It has characteristic IR, max 3640, 1114, 1086, 982 and 930cm-1. [Schleyer & Nicholas J Am Chem Soc 83 182 1961.] [Beilstein 6 IV 391.] Alternatively, if free from the 2-isomer, dissolve it in tetrahydrofuran, dilute with H2O to precipitate the alcohol. Collect, dry and sublime it in a vacuum at 130o. [Stetter et al. Chem Ber 92 1629 1959.]

1-Adamantanol synthesis

36960-53-9
768-95-6
Synthesis of 1-Adamantanol from Tricyclo[3.3.1.13,7]decane, 1-[(trimethylsilyl)oxy]-

1-Adamantanol Preparation Products And Raw materials

Raw materials

Adamantane N-Hydroxyphthalimide Cobalt acetate N,N-Dimethylformamide Sodium thiosulfate
Oxygen Hydrochloric acid Bromine Acetic acid Methanol

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Preparation Products

Phenol, 2-tricyclo[3.3.1.13,7]dec-1-yl- 1-phenoxyadamantane 5-Hydroxyadamantan-2-one 1-(5-Bromo-2-methoxy-phenyl)adamantane CIS-1-BROMO-2-ETHOXYETHYLENE
P-(1-ADAMANTYL)TOLUENE

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1-Adamantanol Suppliers

Global( 555)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Yuanda Chemical Co., Ltd
28-85356300 +8618980937689 sales@ydachem.com CHINA 94 58
Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.
+86-025-86819862 +86-13913839793 sales@jinchemical.com China 29 58
Huzhou Chenxi Environmental Protection Technology Co. , Ltd.
+86-16762203950 1034385273@qq.com China 55 58
Hebei Yanxi Chemical Co., Ltd. 		+86-17531190177 faithe@yan-xi.com China 5838 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1059@dideu.com China 29096 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 sales1@chuanghaibio.com China 5218 58
Hebei Chuanghai Biotechnology Co., Ltd 		+86-17732866630 mina@chuanghaibio.com China 18114 58
Shaanxi Haibo Biotechnology Co., Ltd 		+86-18629295024 qinhe02@xaltbio.com China 996 58
Wuhan JiyunZen Tech Co., Ltd. 		+86-18062099985 Amyjiyunzen@yeah.net China 672 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Supplier Advantage
Chengdu Yuanda Chemical Co., Ltd
58
Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.
58
Huzhou Chenxi Environmental Protection Technology Co. , Ltd.
58
Hebei Yanxi Chemical Co., Ltd. 		58
Dideu Industries Group Limited 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Shaanxi Haibo Biotechnology Co., Ltd 		58
Wuhan JiyunZen Tech Co., Ltd. 		58
Capot Chemical Co.,Ltd. 		60

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Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Adamantanol pictures 2026-08-10 1-Adamantanol
768-95-6
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
1-Adamantanol pictures 2026-07-29 1-Adamantanol
768-95-6
 1kg 99% 1 Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.
1-Adamantanol pictures 2026-05-28 1-Adamantanol
768-95-6
 $10.70 10kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
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1-Adamantanol Spectrum

1-Adamantanol(768-95-6)MS1-Adamantanol(768-95-6)1HNMR1-Adamantanol(768-95-6)13CNMR1-Adamantanol(768-95-6)IR11-Adamantanol(768-95-6)IR21-Adamantanol(768-95-6)Raman

768-95-6(1-Adamantanol)Related Search:

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TRICYCLO[3.3.1.1(3,7)]DECAN-1-OL TRICYCLO[3.3.1.1]DECAN-1-OL 1-HYDROXYDIAMANTANE 1-ADA-OH 1-ADAMANTANOL -Adamantyl alcohol damantol-(1) tricyclo(3.3.1.1(sup3,7))decan-1-ol ADAMANTANOL, 1- AKOS BC-0650 1-Adamantonal 1-Adamantanol,98% LABOTEST-BB LT00436924 ADAMANTANOL, 1-(SG) (1-Adamantyl) alcohol Adamantan-3-ol Hydroxyadamantane 1-Adamantanol,99% Tricyclo[3,3,1,1]3,7 decanol-1 adamantan-1-ol(SALTDATA: FREE) 1-AdaMantanol, 99% 5GR 1-ADAMANTANOL FOR SYNTHESIS 10 G Adapalene IMpurity H Adamantan-1-ol, Tricyclo[3.3.1.1~3,7~]decan-1-ol 1-Adamanthanol/Adamantan-1-ol 1-Admantanol 1-Adamantano 1-Adamantanol Vetec(TM) reagent grade, 98% Tricyclo(3.3.1.1(sup 3,7))decan-1-ol (9CI) 1-AdaMantanol ReagentPlus(R), 99% 1 - adaMantane alcohol 1 Adamentanol (768-95-6) 1-Adamantanol > 1-Adamantanol (6CI, 7CI, 8CI) 1-HYDROXY ADAMANTANE (1-adamantanol) HYDROXY ADAMANTANE (1-ADAMANTANOL) 1-HYDROXYADAMANTANE (3s,5s,7s)-adamantan-1-ol 1-Adamantol 1-Adamatanol 1-AD-OH ADAMANTANOL ADAMANTAN-1-OL 768-95-6 C9 to C30 Alcohols Building Blocks Oxygen Compounds Organic Building Blocks Adamantanes Alcohols Building Blocks C9 to C10 Chemical Synthesis Organic Building Blocks Oxygen Compounds FINE Chemical & INTERMEDIATES Adamantane derivatives