Thalidomide-5-PEG4-COOH
- CAS No.
- 2828438-28-2
- Chemical Name:
- Thalidomide-5-PEG4-COOH
- Synonyms
- Thalidomide-5-PEG4-COOH;3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]oxy]ethoxy]ethoxy]ethoxy]-propanoic Acid;Propanoic acid, 3-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]oxy]ethoxy]ethoxy]ethoxy]-
- CBNumber:
- CB213889034
- Molecular Formula:
- C22H26N2O10
- Molecular Weight:
- 478.45
- MDL Number:
- MOL File:
- 2828438-28-2.mol
Thalidomide-5-PEG4-COOH Chemical Properties,Uses,Production
Uses
Thalidomide-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
IC 50
Cereblon
References
[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-986. DOI:10.7554/eLife.58504
Thalidomide-5-PEG4-COOH Preparation Products And Raw materials
Raw materials
Preparation Products
Thalidomide-5-PEG4-COOH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6585 | 65 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1592 | 58 |
| Supplier | Advantage |
|---|---|
| Daicel Chiral Technologies (China)CO.,LTD | 65 |
| Jilin Province Woda Biotechnology Co., Ltd. | 58 |