3-Fluoropyridine-2-carboxylic acid
- CAS No.
- 152126-31-3
- Chemical Name:
- 3-Fluoropyridine-2-carboxylic acid
- Synonyms
- 3-FLUOROPICOLINIC ACID;3-Fluoropicolinicaci;REF DUPL: 3-fluoropicolinic acid;3-Fluoropyridin-2-carboxylic acid;3-fluropyridine-2-carboxylic acid;3-Fluoro-2-pyridinecarboxylic acid;3-FLUOROPYRIDINE-2-CARBOXYLIC ACID;3-Fluoropyridine-3-Carboxylic Acid;2-Pyridinecarboxylicacid, 3-fluoro-;3-Fluoropyridine-2-carboxylicacid98%
- CBNumber:
- CB2140247
- Molecular Formula:
- C6H4FNO2
- Molecular Weight:
- 141.1
- MDL Number:
- MFCD04114108
- MOL File:
- 152126-31-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Fluoropyridine-2-carboxylic acid Asreported | 276659 | 1g | $340 |
| 3-Fluoropyridine-2-carboxylic acid Asreported | 276659 | 2g | $435 |
| 3-Fluoropyridine-2-carboxylic acid Asreported | 276659 | 5g | $616 |
| 3-Fluoropyridine-2-carboxylic acid Asreported | 276659 | 10g | $828 |
| 3-Fluoropyridine-2-carboxylic acid Asreported | 276659 | 25g | $1204 |
| More product size | |||
| Melting point | 154°C |
|---|---|
| Boiling point | 265.2±20.0 °C(Predicted) |
| Density | 1.419±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| pka | 2.71±0.10(Predicted) |
| form | powder |
| color | White |
| InChI | InChI=1S/C6H4FNO2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,(H,9,10) |
| InChIKey | IRERRSXDWUCFIY-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=NC=CC=C1F |
| CAS DataBase Reference | 152126-31-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
3-Fluoropyridine-2-carboxylic acid price More Price(79)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 276659 | 3-Fluoropyridine-2-carboxylic acid Asreported | 152126-31-3 | 1g | $340 | 2026-06-03 | Buy |
| Usbiological | 276659 | 3-Fluoropyridine-2-carboxylic acid Asreported | 152126-31-3 | 2g | $435 | 2026-06-03 | Buy |
| Usbiological | 276659 | 3-Fluoropyridine-2-carboxylic acid Asreported | 152126-31-3 | 5g | $616 | 2026-06-03 | Buy |
| Usbiological | 276659 | 3-Fluoropyridine-2-carboxylic acid Asreported | 152126-31-3 | 10g | $828 | 2026-06-03 | Buy |
| Usbiological | 276659 | 3-Fluoropyridine-2-carboxylic acid Asreported | 152126-31-3 | 25g | $1204 | 2026-06-03 | Buy |
3-Fluoropyridine-2-carboxylic acid Chemical Properties,Uses,Production
Uses
3-Fluoropyridine-2-carboxylic acid is mainly used as an intermediate in organic synthesis and medicinal chemistry. It is a synthetic intermediate of tridentate nitrogen ligands in pesticide molecules and transition metal catalytic reactions.
Synthesis
372-47-4
124-38-9
152126-31-3
To a diethyl ether (50 ml) solution of 1,4-diazabicyclo[2.2.2]octane (1.15 g, 10.3 mmol) was slowly added n-butyllithium (2.6 M hexane solution, 3.95 ml, 10.3 mmol) dropwise at -78 °C. The reaction mixture was stirred at -20°C for 1 hr, then a diethyl ether (30 ml) solution of 3-fluoropyridine (1.00 g, 10.29 mmol) was added dropwise at -78°C. The resulting yellow suspension was stirred at -60°C for 1 hr and subsequently cooled to -78°C and an excess of dry ice was added. The reaction solution was slowly warmed to -10°C over a period of 20 min. The precipitate was collected by filtration and the residue was washed with ether to give pure 3-fluoropyridine-2-carboxylic acid (1.20 g, 8.51 mmol, 83% yield).
References
[1] Tetrahedron, 1998, vol. 54, # 42, p. 12859 - 12886
[2] Patent: WO2014/82737, 2014, A1. Location in patent: Page/Page column 38
3-Fluoropyridine-2-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| PNP Biotech Co. Ltd | +8618516098983 | sales@pnpbiotech.com | China | 1001 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 3-Fluoropyridine-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 3-FLUOROPYRIDINE-2-CARBOXYLIC ACID
152126-31-3
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-04-04 | 3-Fluoropyridine-2-carboxylicacid
152126-31-3
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2024-03-28 | 3-Fluoropyridine-2-carboxylic acid
152126-31-3
|
25kg | 98% | PNP Biotech Co. Ltd |
-
- 3-FLUOROPYRIDINE-2-CARBOXYLIC ACID
152126-31-3
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-Fluoropyridine-2-carboxylicacid
152126-31-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 3-Fluoropyridine-2-carboxylic acid
152126-31-3
- $0.00
- 98%
- PNP Biotech Co. Ltd
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