ChemicalBook >> CAS DataBase List >>Uridine-5'-diphosphate disodium salt

Uridine-5'-diphosphate disodium salt

Uridine-5'-diphosphate disodium salt structure

CAS No.: 27821-45-0

Chemical Name:: Uridine-5'-diphosphate disodium salt

Synonyms: UDP 2NA;UDP.Na2;5′-UDP,2Na;5'-UDP-Na2;Einecs 248-678-9;5'-UDP 2Na Hydrate;Diquafosol Impurity 17;Uridine 5’-diphosphate;Sodium 1-((2R,3R,4S,5R);Disodiumuridinediphosphate

CBNumber:: CB2143213

Molecular Formula:: C9H15N2NaO12P2

Molecular Weight:: 428.16

MDL Number:: MFCD00084679

MOL File:: 27821-45-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
Uridine 5′-diphosphate disodium salt hydrate ≥96.0% (HPLC)	94330	100mg	$139
Uridine 5′-diphosphate disodium salt hydrate ≥96.0% (HPLC)	94330	500mg	$588
UDP (sodium salt) ≥95%	18137	100mg	$32
UDP (sodium salt) ≥95%	18137	1g	$109
UDP (sodium salt) ≥95%	18137	500mg	$70
More product size

Request For Quotation

Uridine-5'-diphosphate disodium salt Properties

storage temp.	-20°C
form	Powder
color	White to Off-white
biological source	synthetic
Water Solubility	Slightly soluble in water.
Sensitive	Moisture Sensitive
BRN	8817400
InChIKey	KWDGQJWFEYTPBN-IBOJMDDDSA-L
SMILES	O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] \|&1:1,2,3,15,r\|
CAS DataBase Reference	27821-45-0(CAS DataBase Reference)
FDA UNII	CU84BH96WL
UNSPSC Code	41106305
NACRES	NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
F	10-21
HS Code	29349990
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

Uridine-5'-diphosphate disodium salt price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	94330	Uridine 5′-diphosphate disodium salt hydrate ≥96.0% (HPLC)	27821-45-0	100mg	$139	2026-04-30	Buy
Sigma-Aldrich	94330	Uridine 5′-diphosphate disodium salt hydrate ≥96.0% (HPLC)	27821-45-0	500mg	$588	2026-04-30	Buy
Cayman Chemical	18137	UDP (sodium salt) ≥95%	27821-45-0	100mg	$32	2024-03-01	Buy
Cayman Chemical	18137	UDP (sodium salt) ≥95%	27821-45-0	1g	$109	2024-03-01	Buy
Cayman Chemical	18137	UDP (sodium salt) ≥95%	27821-45-0	500mg	$70	2024-03-01	Buy

Product number	Packaging	Price	Buy
94330	100mg	$139	Buy
94330	500mg	$588	Buy
18137	100mg	$32	Buy
18137	1g	$109	Buy
18137	500mg	$70	Buy

Uridine-5'-diphosphate disodium salt Chemical Properties,Uses,Production

Description

Uridine-5'-diphosphate disodium salt (UDP-Na2) is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). It is an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis. It has also been used as a purinergic agonist, in order to study its effect on the flux of absorbed cations in cochlear outer sulcus cells (OSC) and vestibular migratory cells (VTC). UDP-Na2 has also been used to determine the activity of nucleoside diphosphatase (NDPase) in the rabbit retina.

Uses

Uridine-5'-diphosphate disodium salt is mainly used in nucleic acid (RNA) biosynthesis and cell signalling studies. Uridine-5'-monophosphate disodium salt (UDP-MS) is a structural analogue of uridine and is used as a dietary supplement. It has been shown to inhibit phosphodiesterase and cyclic nucleotide phosphodiesterase, both of which are enzymes that degrade the secondary messenger cyclic adenosine monophosphate (cAMP).

Uses

Uridine-5'-diphosphate disodium salt (UDP-Na2) is an organometallic compound, It is a P2Y6 receptor agonist and GPR105 receptor inhibitor. It is used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled Protein Receptors (GPCR) and cell signaling molecules such as Rho-signaling via Guanine Nucleotide Exchange Factors (GEF).

Application

Uridine-5'-diphosphate disodium salt hydrate has been used:
as a standard for quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC/MS)
as a UDP standard for nucleotide analysis by liquid chromatography-high resolution mass spectrometry (LC-HRMS)
to treat E6.5 retina explants in vitro, to study its effect on the entry and elongation of microglial cells into the embryonic quail retina

Biochem/physiol Actions

Uridine-5'-diphosphate disodium salt is an endogenous signaling molecule produced by damaged cells to attract macrophages. In response to neuronal damage, UDP promotes chemotaxis and chemokinesis in microglial cells. UDP serves as a ligand for P2Y receptors. UDP and uridine 5′-triphosphate (UTP) may be used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled protein receptors (GPCR) and cell signaling molecules such as Rho-signaling via guanine nucleotide exchange factors (GEF).

storage

Store at -20°C

Purification Methods

Crystallise it from MeOH. It may contain some Ba salt(s); hence stir it with Amberlite IR-120 cation exchanger (25mL, wet resin, 15-50 mesh in H+ form) in H2O (50mL) until the nucleotide dissolves. Filter, wash resin with H2O until the eluate is neutral. Combine the filtrate and washings, and adjust the pH to 8.0 with 2.0 M aqueous NaOH. Concentrate it in vacuo to a small volume (~ 20mL), and add Me2CO dropwise until crystallisation begins. Cool to 0o, and the shiny plates of di Na uridine-5’-phosphate dihydrate are filtered off and dried over P2O5 at 25o/0.1mm for 24hours (>76% recovery). UV: max at 262nm ( 10,000 M-1cm -1) in 0.1 M HCl. [Boon et al. J Chem Soc 408 1950, Smith Biochemical Preparations 8 130 1960.] [Beilstein 24 IV 1214.]

Uridine-5'-diphosphate disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

Uridine-5'-diphosphate disodium salt Suppliers

Global( 393)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	17259	58
WeiTai BioPharmaceutical Co.,Ltd(Hangzhou)	+86-57182358004 13588810720	sales1@weitai-pharmaceutical.com	China	61	58
Hangzhou Meiya Pharmaceutical Co Ltd	+86-021-33686691 +86-18001850931	sales@meiyapharm.com	China	58	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	4000	58
Shaanxi Dideu Medichem Co. Ltd	+8617392709771	1097@dideu.com	China	3996	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5235	58
HangZhou RunYan Pharma Technology Co.,LTD.	+8618882027439	sales2@runyanpharma.com	China	302	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55

Supplier	Advantage
CD Chemical Group Limited	58
WeiTai BioPharmaceutical Co.,Ltd(Hangzhou)	58
Hangzhou Meiya Pharmaceutical Co Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
HangZhou RunYan Pharma Technology Co.,LTD.	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55

Related Qustion

Ask a question

Q:What are the biological functions of uridine 5’-diphosphate disodium salt (UDP-Na2)?jia - Nov 5，2025

A:Uridine 5'-diphosphate disodium salt (UDP- Na2) is a fundamental building block of RNA biosynthesis. After phosphorylation to uridine triphosphate (UTP), it serves as a substrate for various enzymes, including RNA polymerase, which is involved in the transcription of genetic information. UDP-Na2 plays a crucial role in carbohydrate metabolism, participating in glycosylation, which is essential for the formation of glycoproteins and glycolipids. As a signaling molecule, UDP-Na2 can interact with specific purinergic receptors (such as the P2Y6 receptor), thereby influencing a range of cellular activities, such as inflammatory responses and cytoskeleton dynamics. It is a potent and selective natural agonist of the P2Y6 receptor.

View Lastest Price from Uridine-5'-diphosphate disodium salt manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-30	Uridine-5'-diphosphoglucose disodium salt 27821-45-0	US $12.00 / KG	1KG	99%	200mt/year	Jinan Finer Chemical Co., Ltd
2026-04-30	Uridine-5'-diphosphoglucose disodium salt 27821-45-0	US $0.00 / g	1g	98%	10kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-04-28	uridine 5'-diphosphate disodium salt 27821-45-0	US $0.00 / Kg	1Kg	98%	20Ton	Xinxiang Aurora Biotechnology Co.,Ltd.

Uridine-5'-diphosphoglucose disodium salt
27821-45-0
US $12.00 / KG
99%
Jinan Finer Chemical Co., Ltd

Uridine-5'-diphosphoglucose disodium salt
27821-45-0
US $0.00 / g
98%
WUHAN FORTUNA CHEMICAL CO., LTD

uridine 5'-diphosphate disodium salt
27821-45-0
US $0.00 / Kg
98%
Xinxiang Aurora Biotechnology Co.,Ltd.

Uridine-5'-diphosphate disodium salt Spectrum

Uridine-5'-diphosphate disodium salt(27821-45-0)¹HNMR Uridine-5'-diphosphate disodium salt(27821-45-0)¹³CNMR

27821-45-0(Uridine-5'-diphosphate disodium salt)Related Search:

Pamidronate disodium salt Doxifluridine 1-beta-D-Arabinofuranosyluracil Ethylenediaminetetraacetic acid disodium salt Sodium Monofluorophosphate

Uridine-5'-triphosphoric acid trisodium salt Uridine 5′-monophosphate disodium salt Uridine UDP URODILATIN HUMAN

Uridine Diphosphate Choline Diquafosol UDP-rhamnose Clodronate disodium Salt Uridine 5'-monophosphate

Sodium Phosphate, Dibasic Guanosine-5'-diphosphate disodium salt Uridine 5'-diphosphoglucose disodium salt from Saccharomyces cerevisiae

1of4

UDP 2NA URIDINE 5'-DIPHOSPHORIC ACID DISODIUM SALT Uridine 5'-diphosphate disodiu salt Diquafosol Impurity 2(UDP Sodium Salt) 5'-UDP-Na2 Uridine 5'-(trihydrogen diphosphate), disodium salt UDP(URIDINE-5''-DIPHOSPHATE) URIDINE-5''- DIPHOSPHATE, DISODIUM SALT(UDP.NA2) URIDINE-5''-DIPHOSPHATE DISODIUM SALT HYDRATE (UDP) URIDINE 5''- DIPHOSPHATE DISODIUM SALT (5''-UDP-NA2) Uriidine-5'-diphosphate, disodium salt Uridine-5'-diphosphoglucose disodium salt Einecs 248-678-9 5′-UDP,2Na UDP.Na2 SodiuM 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyriMidin-5-yl hydrogendiphosphate -2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl hydrogendiphosphate Sodium 1-((2R,3R,4S,5R) 5'-UDP 2Na Hydrate Uridine 5'-diphosphate disodium salt hydrate, ≥96.0% (HPLC) Uridine-5'-diphosphoglucose disodium salt (UDP) Uridine 5'-diphosphate disodium salt hyd ridine 5'-diphosphate disodium salt Uridine 5'-(trihydrogen diphosphate), sodium salt (1:2) Uridine 5'-diphosphoric acid disodium Uridine-5-diphosphate disodium Uridine 5'-diphosphate Disodium Salt Monohydrate Uridine -5- disodium diphosphate sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate, sodium salt glucuronidation,Endogenous Metabolite,nucleic,P2Y6,P2Y14,P2Y Receptor,substrates,Uridine5'diphosphate disodium salt,inhibit,Inhibitor,acid,Uridine 5' diphosphate disodium salt,DNA/RNA Synthesis Uridine 5＇-diphosphate disodium salt ·X Hydrate Diquafosol Impurity 17 Uridine -5'- diphosphate disodium salt(UDP-Na,) Uridine 5’-diphosphate Uridine 5'-diphosphate disodium salt hydrate Uridine 5'-diphosphate disodium salt (UDP- Na2) Uridine 5'-diphosphate Disodium Salt Uridine-5'-diphosphate sodium salt (UDP) Uridine-5''-diphosphate disodium salt UDP·Na2, Uridine 5''-diphosphate disodium salt hydrate Uridine-5''-diphosphate disodium salt, 10 mM in DMSO Disodiumuridinediphosphate Disodium hydrogen ({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate 27821-45-0 C9H12N2Na2O12P2 C9H12N2Na2O12P23H2O C9H12N2Na2O12P2xH2O C9H12N2O13P22Na BioChemical Biochemicals and Reagents Nucleotides Nucleosides, Nucleotides, Oligonucleotides Material Pharmaceutical API 27821-45-0