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BOC-PHE-ONP

BOC-PHE-ONP structure

CAS No.: 7535-56-0

Chemical Name:: BOC-PHE-ONP

Synonyms: BOC-PHE-ONP;Boc-L-Phe-ONp;BOC-PHENYLALANINE-ONP;BOC-PHE-ONP USP/EP/BP;Boc-Phe-(4-Nitrophenyl)OH;(Tert-Butoxy)Carbonyl Phe-ONp;Boc-L-phenylanine-4-nitropheny ester;BOC-L-PHENYLALANINE P-NITROPHENYL ESTER;BOC-L-PHENYLALANINE 4-NITROPHENYL ESTER;N-Boc-L-Phenylalanine 4-nitrophenyl ester

CBNumber:: CB2150048

Molecular Formula:: C20H22N2O6

Molecular Weight:: 386.4

MDL Number:: MFCD00042811

MOL File:: 7535-56-0.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:49

Product description	Number	Pack Size	Price
Boc-L-phenylalanine 4-nitrophenyl ester	264826	25g	$383
Boc-Phe-ONP	B662045	50mg	$45
Boc-L-phenylalanine 4-nitrophenyl ester ≥ 99% (HPLC)	03807	25G	$45
4-Nitrophenyl(tert-butoxycarbonyl)-L-phenylalaninate	CS-M0809	1g	$165
BOC-PHE-ONP 95.00%	AAA0003689	25G	$165.48
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BOC-PHE-ONP Properties

Melting point	127-128 °C
Boiling point	558.4±50.0 °C(Predicted)
Density	1.240±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
pka	10.83±0.46(Predicted)
form	Crystalline Powder
color	White
Sensitive	Moisture Sensitive
CAS DataBase Reference	7535-56-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

WGK Germany

3-10-21

NFPA 704

	1
0		0

BOC-PHE-ONP price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	264826	Boc-L-phenylalanine 4-nitrophenyl ester	7535-56-0	25g	$383	2021-12-16	Buy
TRC	B662045	Boc-Phe-ONP	7535-56-0	50mg	$45	2021-12-16	Buy
Chem-Impex	03807	Boc-L-phenylalanine 4-nitrophenyl ester ≥ 99% (HPLC)	7535-56-0	25G	$45	2021-12-16	Buy
ChemScene	CS-M0809	4-Nitrophenyl(tert-butoxycarbonyl)-L-phenylalaninate	7535-56-0	1g	$165	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0003689	BOC-PHE-ONP 95.00%	7535-56-0	25G	$165.48	2021-12-16	Buy

Product number	Packaging	Price	Buy
264826	25g	$383	Buy
B662045	50mg	$45	Buy
03807	25G	$45	Buy
CS-M0809	1g	$165	Buy
AAA0003689	25G	$165.48	Buy

BOC-PHE-ONP Chemical Properties,Uses,Production

Uses

4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate is a phenylalanine derivative[1].

Synthesis

100-02-7

13734-34-4

7535-56-0

The general procedure for the synthesis of Boc-L-aniline-4-nitrophenyl ester from 4-nitrophenol and Boc-L-phenylalanine is as follows: dissolve N-tert-butoxycarbonyl-L-phenylalanine (50 g) in dichloromethane (800 ml), stirring until completely dissolved. P-nitrophenol (39 g), 4-dimethylaminopyridine (DMAP, 3 g) and dicyclohexylcarbodiimide (DCC, 39 g) were added and the reaction was carried out for 5 hours at about 20°C. After completion of the reaction, the reaction mixture was filtered and the filtrate was evaporated. Ethanol was added to the residue and heated until complete dissolution, then slowly cooled to 20-30°C to allow the solid to precipitate gradually. Water (50 ml) was added and the mixture was cooled to 0°C and crystallized for 1 hour. The solid was collected by filtration to afford the target product Boc-L-aniline-4-nitrophenyl ester (62 g, 86.5% yield, 93% purity).

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-855. DOI:10.1080/10408398.2012.708368

BOC-PHE-ONP Preparation Products And Raw materials

Raw materials

4-Nitrophenol N-(tert-Butoxycarbonyl)-L-phenylalanine Dicyclohexylcarbodiimide 4-Dimethylaminopyridine Dichloromethane

Preparation Products

BOC-PHE-ONP Suppliers

Global( 102)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+8618382028708	ni@enlaibio.com	China	1098	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10404	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9540	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
GL Biochem(Binhai) Ltd.	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from BOC-PHE-ONP manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-30	Boc-L-Phe-Onp 7535-56-0	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
	2020-01-15	BOC-PHE-ONP 7535-56-0	US $1.00 / g	100g	>98%	g/kg/Ton	Career Henan Chemical Co

Boc-L-Phe-Onp
7535-56-0
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

BOC-PHE-ONP
7535-56-0
US $1.00 / g
>98%
Career Henan Chemical Co

7535-56-0(BOC-PHE-ONP)Related Search:

Aniline BOC-TYR-ONP N-Boc-L-Phenylalaninol BOC-ABU-ONP BOC-PHE-ONP

BOC-L-ALANINE METHYL ESTER Phenylalanine-N-carboxylic acid dimethyl ester BOC-DL-PHENYLALANINE METHYL ESTER N-(tert-Butoxycarbonyl)-L-phenylalanine BOC-ALA-ONP

BOC-GLY-ONP N-Boc-L-phenylalaninal 4-(3-phenylpropoxy)phenylamine BOC-O-BENZYL-L-TYROSINE 4-NITROPHENYL ESTER BOC-PHE-OME

FOR-PHE-OME

1of4

N-TERT-BUTOXYCARBONYL-L-PHENYLALANINE-P-NITROPHENYL ESTER 4-nitrophenyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoate N-[(1,1-Dimethylethoxy)Carbonyl]-L-Phenylalanine 4-Nitrophenyl Ester (Tert-Butoxy)Carbonyl Phe-ONp (S)-4-Nitrophenyl2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate N-(tert-Butyloxycarbonyl)-L-phenylalanine p-nitrophenyl ester Boc-L-phenylalanine 4-nitrophenyl ester≥ 99% (HPLC) BOC-PHENYLALANINE-ONP BOC-PHE-ONP BOC-L-PHENYLALANINE 4-NITROPHENYL ESTER BOC-L-PHENYLALANINE P-NITROPHENYL ESTER 4-nitrophenyl N-(tert-butoxycarbonyl)-3-phenyl-L-alaninate N-alpha-t-boc-L-phenylalanine-p-nitrophenylester,crystalline n-alpha-t-boc-l-phenylalanine-p-nitrophenylestercrystalline N-tert-Butoxycarbonyl-L-phenylalanine 4-nitrophenyl ester Boc-L-Phe-ONp N-alpha-t-Butyloxycarbonyl-L-phenylalanine p-nitrophenyl ester N-(tert-butoxycarbonyl)-L-phenylalanine-4-nitrophenyl Boc-Phe-(4-Nitrophenyl)OH N-(tert-Butyloxycarbonyl)-L-phenylalanine 4-nitrophenyl ester N-Boc-L-Phenylalanine 4-nitrophenyl ester Boc-L-phenylanine-4-nitropheny ester 4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, 4-nitrophenyl ester (4-nitrophenyl)(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoate BOC-PHE-ONP USP/EP/BP Boc-l-phenylalanine 4-nitrophenyl ester, 98%+ BOC-4-Nitro-L-Phenylalanine Ethyl Ester extrapure, 98% 4-Nitrophenyl (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoate (N-BOC-L-Phenylalanine 4-Nitrophenyl Ester) N-Boc-L-phenylalanine p-nitrophenyl ester 4-Nitrophenyl (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoate (N-BOC-L-Phenylalanine 4-Nitrophe (S)-4-Nitrophenyl 2-(N-BOC-amino)-3-phenylpropanoate 7535-56-0 7536-56-0 Amino Acid Derivatives Peptide Synthesis Phenylalanine Specialty Synthesis Amino Acids