2',6'-DIMETHYLACETANILIDE
- CAS No.
- 2198-53-0
- Chemical Name:
- 2',6'-DIMETHYLACETANILIDE
- Synonyms
- Lidocaine EP Impurity C;NSC 54130;2,6-Acetoxylide;2’,6’-Acetoxylidid;LIDOCAINE EP IMP C;2',6'-ACETOXYLIDIDE;TIMTEC-BB SBB008144;Lidocaine Impurity 7;N-ACETYL-2,6-XYLIDINE;N-Acetyl-2,6-xylidene
- CBNumber:
- CB2161927
- Molecular Formula:
- C10H13NO
- Molecular Weight:
- 163.22
- MDL Number:
- MFCD00008675
- MOL File:
- 2198-53-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2′,6′-Dimethylacetanilide 97% | 126357 | 25g | $89.8 |
| 2′,6′-Dimethylacetanilide (Lidocaine RCC) Pharmaceutical Secondary Standard; Certified Reference Material | PHR1671 | 100mg | $544 |
| N-(2,6-Dimethylphenyl)acetamide >95%(HPLC) | TRC-D446680-50G | 50g | $222 |
| N-(2,6-Dimethylphenyl)acetamide >95%(HPLC) | TRC-D446680-1G | 1g | $116 |
| N-(2,6-Dimethylphenyl)acetamide >95%(HPLC) | TRC-D446680-100MG | 100mg | $81 |
| More product size | |||
| Melting point | 182-184 °C(lit.) |
|---|---|
| Boiling point | 290.31°C (rough estimate) |
| Density | 1.052 |
| refractive index | 1.5400 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 15.14±0.70(Predicted) |
| color | Crystals |
| InChI | 1S/C10H13NO/c1-7-5-4-6-8(2)10(7)11-9(3)12/h4-6H,1-3H3,(H,11,12) |
| InChIKey | NRPTXWYBRKRZES-UHFFFAOYSA-N |
| SMILES | CC(=O)Nc1c(C)cccc1C |
| CAS DataBase Reference | 2198-53-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 68GZI4J9FM |
| EPA Substance Registry System | Acetamide, N-(2,6-dimethylphenyl)- (2198-53-0) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AN7470000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29242990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Toxicity | LD50 orl-mus: 620 mg/kg TXAPA9 19,20,71 | |||||||||
| NFPA 704 |
|
2',6'-DIMETHYLACETANILIDE price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 126357 | 2′,6′-Dimethylacetanilide 97% | 2198-53-0 | 25g | $89.8 | 2023-06-20 | Buy |
| Sigma-Aldrich | PHR1671 | 2′,6′-Dimethylacetanilide (Lidocaine RCC) Pharmaceutical Secondary Standard; Certified Reference Material | 2198-53-0 | 100mg | $544 | 2022-05-15 | Buy |
| TRC | TRC-D446680-50G | N-(2,6-Dimethylphenyl)acetamide >95%(HPLC) | 2198-53-0 | 50g | $222 | 2026-06-03 | Buy |
| TRC | TRC-D446680-1G | N-(2,6-Dimethylphenyl)acetamide >95%(HPLC) | 2198-53-0 | 1g | $116 | 2026-06-03 | Buy |
| TRC | TRC-D446680-100MG | N-(2,6-Dimethylphenyl)acetamide >95%(HPLC) | 2198-53-0 | 100mg | $81 | 2026-06-03 | Buy |
2',6'-DIMETHYLACETANILIDE Chemical Properties,Uses,Production
Chemical Properties
off-white to yellow cryst. needles or cryst.powder
Uses
Lidocaine (L397800) impurity.
Synthesis Reference(s)
Journal of the American Chemical Society, 106, p. 5759, 1984 DOI: 10.1021/ja00331a073
Chemical and Pharmaceutical Bulletin, 30, p. 4242, 1982 DOI: 10.1248/cpb.30.4242
Journal of Heterocyclic Chemistry, 2, p. 181, 1965 DOI: 10.1002/jhet.5570020214
General Description
2,6-Dimethylacetanilide undergoes iodination by electrophylic substitution reaction of chloroacetanilide, in the presence of ferroiodide and copperchloride as catalyst, to form 4-iodine-2,6-dimethylacetanilide.
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits toxic fumes ofNOx.
2',6'-DIMETHYLACETANILIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Sense Chemicals (Shanghai) Co., Ltd. | +86-21-52751036; +8613818977689 | david.dai@sensechemicals.com | China | 225 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
View Lastest Price from 2',6'-DIMETHYLACETANILIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-12 | Lidocaine EP Impurity C
2198-53-0
|
10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | ||
![]() |
2025-12-01 | 2,6-Dimethylacetanilide
2198-53-0
|
1kg | 98% | 10000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
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2020-02-01 | 2',6'-DIMETHYLACETANILIDE
2198-53-0
|
$3.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-

- Lidocaine EP Impurity C
2198-53-0
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-

- 2,6-Dimethylacetanilide
2198-53-0
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- 2',6'-DIMETHYLACETANILIDE
2198-53-0
- $3.00
- 98%
- Career Henan Chemical Co
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