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H-TYR-D-ALA-GLY-PHE-D-LEU-OH

H-TYR-D-ALA-GLY-PHE-D-LEU-OH structure

CAS No.: 63631-40-3

Chemical Name:: H-TYR-D-ALA-GLY-PHE-D-LEU-OH

Synonyms: YAGFL;DADLE;BW-180;BW-180C;BW-180C, 10 mM in DMSO;TYR-D-ALA-GLY-PHE-D-LEU;(D-ALA2,D-LEU5)-ENKEPHALIN;H-TYR-D-ALA-GLY-PHE-D-LEU-OH;Enkephalin, Leucine-2-Alanine;TYR-D-ALA-GLY-PHE-D-LEU ACOH H2O

CBNumber:: CB2167318

Molecular Formula:: C29H39N5O7

Molecular Weight:: 569.65

MDL Number:: MFCD00076411

MOL File:: 63631-40-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-11 16:31:51

Product description	Number	Pack Size	Price
DADLE ≥98%	28928	1mg	$36
DADLE ≥98%	28928	5mg	$103
DADLE ≥98%	28928	10mg	$186
DADLE ≥98%	28928	50mg	$835
DADLE	28928	5mg	$93

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H-TYR-D-ALA-GLY-PHE-D-LEU-OH Properties

Melting point	>167°C (dec.)
Boiling point	991.9±65.0 °C(Predicted)
Density	1.257±0.06 g/cm3(Predicted)
storage temp.	-15°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.40±0.10(Predicted)
form	Solid
color	White to Off-White
Water Solubility	Soluble to 1 mg/ml in water
Stability	Hygroscopic
FDA UNII	HB4QD9GL6F

H-TYR-D-ALA-GLY-PHE-D-LEU-OH price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	28928	DADLE ≥98%	63631-40-3	1mg	$36	2026-04-30	Buy
Cayman Chemical	28928	DADLE ≥98%	63631-40-3	5mg	$103	2026-04-30	Buy
Cayman Chemical	28928	DADLE ≥98%	63631-40-3	10mg	$186	2026-04-30	Buy
Cayman Chemical	28928	DADLE ≥98%	63631-40-3	50mg	$835	2026-04-30	Buy
Cayman Chemical	28928	DADLE	63631-40-3	5mg	$93	2024-03-01	Buy

Product number	Packaging	Price	Buy
28928	1mg	$36	Buy
28928	5mg	$103	Buy
28928	10mg	$186	Buy
28928	50mg	$835	Buy
28928	5mg	$93	Buy

H-TYR-D-ALA-GLY-PHE-D-LEU-OH Chemical Properties,Uses,Production

Uses

DADLE is a selective δ-OR agonist.

in vivo

BW-180C ( [D-Ala2, D-Leu5]-Enkephalin; DADLE) protects liver against ischemia-reperfusion injury in the rat. DADLE (5 mg/kg) protects the heart, lung, and jejunum against ischemia-reperfusion (I-R) injury^[2].
BW-180C (DADLE) improves hepatic ischemia/reperfusion injury in mice via activation of the Nrf2/HO1 pathway^[3].
DADLE (5 mg/kg) significantly reduces the levels of alanine aminotransferase and aspartate aminotransferase in the serum, and the levels of malondialdehyde in the liver homogenate^[3].

Animal Model:	Male Wistar rats weighing 200 to 250 g^[2]
Dosage:	5 mg/kg
Administration:	Administered intravenously into the inferior vena cava
Result:	After 120 min of reperfusion, the serum GPT levels were significantly lower in the DADLE group than in the Control group.

Animal Model:	Male C57BL/6 mice (age, 35-42 days; weight, 18-22 g; 6 mice in each group)^[3]
Dosage:	5 mg/kg
Administration:	Injected intraperitoneally 15 min prior to I/R
Result:	The serum levels of AST and ALT in the serum DADLE group were significantly lower.

storage

Store at -20°C

H-TYR-D-ALA-GLY-PHE-D-LEU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-TYR-D-ALA-GLY-PHE-D-LEU-OH Suppliers

Global( 104)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28509	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
Nanjing TGpeptide	+86-13347807150	support@tgpeptide.com	China	3279	58

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
career henan chemical co	58
Dideu Industries Group Limited	58
BOC Sciences	58
Zhejiang J&C Biological Technology Co.,Limited	58
Nextpeptide Inc	58
Chengdu Youngshe Chemical Co., Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
Nanjing TGpeptide	58

View Lastest Price from H-TYR-D-ALA-GLY-PHE-D-LEU-OH manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	BW-180C 63631-40-3	$35.00-89.00		100.00%	10g	TargetMol Chemicals Inc.
	2020-02-19	H-TYR-D-ALA-GLY-PHE-D-LEU-OH 63631-40-3	$7.00	1KG	99%	100kg	Career Henan Chemical Co

BW-180C
63631-40-3
$35.00-89.00
100.00%
TargetMol Chemicals Inc.

H-TYR-D-ALA-GLY-PHE-D-LEU-OH
63631-40-3
$7.00
99%
Career Henan Chemical Co

63631-40-3(H-TYR-D-ALA-GLY-PHE-D-LEU-OH)Related Search:

Semaglutide PENTAGLYCINE H-HIS-LEU-OH [LEU5]-ENKEPHALIN GLYCYL-D-LEUCINE

AC-D-NVA-OH TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT D-2-Amino-4-methylpentanoic acid GLY-GLY-D-LEU H-TYR-D-ALA-GLY-PHE-D-LEU-OH

N-Acetyl-D-leucine (2-D-ALANINE-5-D-LEUCINE), [TYROSYL-3,-3H(N)]-

1of3

YAGFL TYR-D-ALA-GLY-PHE-D-LEU TYR-D-ALA-GLY-PHE-D-LEU ACOH H2O H-TYR-D-ALA-GLY-PHE-D-LEU-OH (D-ALA2,D-LEU5)-ENKEPHALIN [D-ALA2,D-LEU5]-ENKEPHALIN ACOH H2O DADLE Enkephalin, Leucine-2-Alanine (D-Ala2,D-Leu5)-Enkephalinv MW : 2-D-Alanine-5-D-leucine-enkephalin BW-180 (D-Ala2,D-Leu5)-Enkephalin H-Tyr-D-Ala-Gly-Phe-D-Leu-OH D-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl- H-TYR-D-ALA-GLY-PHE-D-LEU-OH USP/EP/BP L-Tyrosyl-D-Alanylglycyl-L-Phenylalanyl-D-Leucine BW-180C BW-180C,BW180C,Inhibitor,Opioid Receptor,inhibit,BW 180C (D-Ala?,D-Leu?)-Enkephalin acetate salt DADLE, delta-Opioid peptide agonist BW-180C, 10 mM in DMSO 63631-40-3 peptide