ChemicalBook >> CAS DataBase List >>4-Nitrobenzoyl chloride

4-Nitrobenzoyl chloride

CAS No.
122-04-3
Chemical Name:
4-Nitrobenzoyl chloride
Synonyms
P-NITROBENZOYL CHLORIDE;PNBC;4-Nitrobenzoyl;SKL748;4-Nitrobenzoyl chlor;p-Nitrobenzoyl chlori;LABOTEST-BB LT00077260;4-nitro-benzoylchlorid;p-nitro-benzoylchlorid;NITROBENZOYL-4 CHLORIDE
CBNumber:
CB2182076
Molecular Formula:
C7H4ClNO3
Molecular Weight:
185.56
MDL Number:
MFCD00007345
MOL File:
122-04-3.mol
MSDS File:
SDS
Last updated:2025-09-25 17:15:13
Product description Number Pack Size Price
4-Nitrobenzoyl chloride for synthesis 8.06772 5G $26.9
4-Nitrobenzoyl chloride for synthesis 8.06772 250g $114
4-Nitrobenzoyl chloride 98% 112208 50g $45
4-Nitrobenzoyl chloride 98% 112208 250g $96.7
4-Nitrobenzoyl Chloride >98.0%(GC)(T) N0176 25g $22
More product size

4-Nitrobenzoyl chloride Properties

Melting point 71-74 °C (lit.)
Boiling point 202-205 °C/105 mmHg (lit.)
Density 1.53
refractive index 1.5890 (estimate)
Flash point 102 °C
storage temp. Store below +30°C.
solubility Soluble in terahydrofuran, dichloromethane, chloroform and pyridine.
form Flakes or Crystals
color Yellow
Odor pungent odor
Water Solubility Decomposes
Sensitive Moisture Sensitive
Merck 14,6589
BRN 473192
Stability Stable, but moisture sensitive. Combustible. Incompatible with water, alcohols, strong oxidizing agents, strong bases.
InChIKey SKDHHIUENRGTHK-UHFFFAOYSA-N
CAS DataBase Reference 122-04-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII X3H8PW2GC4
NIST Chemistry Reference 4-Nitrobenzoic acid chloride(122-04-3)
EPA Substance Registry System p-Nitrobenzoyl chloride (122-04-3)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P305+P351+P338-P310
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3261 8/PG 2
WGK Germany  2
RTECS  DM6651000
9-19-21
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29163900
Toxicity LD50 orally in Rabbit: 5600 mg/kg
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 2
W

4-Nitrobenzoyl chloride price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.06772 4-Nitrobenzoyl chloride for synthesis 122-04-3 5G $26.9 2025-07-31 Buy
Sigma-Aldrich 8.06772 4-Nitrobenzoyl chloride for synthesis 122-04-3 250g $114 2025-07-31 Buy
Sigma-Aldrich 112208 4-Nitrobenzoyl chloride 98% 122-04-3 50g $45 2025-07-31 Buy
Sigma-Aldrich 112208 4-Nitrobenzoyl chloride 98% 122-04-3 250g $96.7 2025-07-31 Buy
TCI Chemical N0176 4-Nitrobenzoyl Chloride >98.0%(GC)(T) 122-04-3 25g $22 2025-07-31 Buy
Product number Packaging Price Buy
8.06772 5G $26.9 Buy
8.06772 250g $114 Buy
112208 50g $45 Buy
112208 250g $96.7 Buy
N0176 25g $22 Buy

4-Nitrobenzoyl chloride Chemical Properties,Uses,Production

Chemical Properties

yellow needles or powder

Uses

4-Nitrobenzoyl Chloride is used inorganic syntheses such as Michael additions. Also used in the synthesis of polysubstituted furanonaphthoquinoines.

Uses

4-Nitrobenzoyl chloride is used in the preparation of polysubstituted furanonaphthoquinoines. It is also involved in Michael addition, Henry reaction, O-alkylation and cycloaddition reactions. Further, it is employed as an intermediate in active pharmaceutical ingredient and dyes.

General Description

Yellow needles or powder with a pungent odor.

Air & Water Reactions

Unstable in moist surroundings and should be kept in a tightly-closed container. React with water or steam .

Reactivity Profile

4-Nitrobenzoyl chloride is incompatible with bases (including amines), with strong oxidizing agents, and with alcohols. May react with reducing agents. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Flash point data are not available for 4-Nitrobenzoyl chloride, but 4-Nitrobenzoyl chloride is combustible.

Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and Cl-. See also NITRO COhlPOUNDS OF AROMATIC HYDROCARBONS and CHLORIDES.

Purification Methods

Crystallise the acid chloride from dry pet ether (b 60-80o), *C6H6 or CCl4. Distil it under vacuum. Irritant. [Adama & Jenkins Org Synth Coll Vol I 394 1941, Beilstein 9 III 1709, 9 IV 1191.]

Global( 43)Suppliers
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Hebei Junhua Import and Export Co., LTD
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Jinan Carbotang Biotech Co.,Ltd.
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GetChem Co., Ltd.
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View Lastest Price from 4-Nitrobenzoyl chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Nitrobenzoyl chloride pictures 2025-10-16 4-Nitrobenzoyl chloride
122-04-3
US $0.00 / kg 1kg 99% 1000 Hebei Junhua Import and Export Co., LTD
4-NITROBENZOYL CHLORIDE 4-NITROBENZOIC ACID CHLORIDE LABOTEST-BB LT00077260 P-NITROBENZOYL CHLORIDE NITROBENZOYL-4 CHLORIDE 4-nitro-benzoylchlorid Benzoyl chloride, 4-nitro- Benzoyl chloride, p-nitro- Benzoylchloride,4-nitro- Nitrobenzoyl chloride, 4- p-Nitrobenzoic acid chloride p-nitrobenzoicacidchloride p-nitro-benzoylchlorid 4-Nitrobenzoic acid chloran hydride 4-Nitrobenzenecarbonyl chloride 4-Nitrobenzoyl chloride,98% 4-Nitrobenzoyl chlor 4-(Chlorocarbonyl)nitrobenzene 4-Nitrobenzoyl chloride, 98% 100GR 4-Nitrobenzoyl chloride, 98% 5GR 4-NITROBENZOYL CHLORIDE FOR SYNTHESIS p-Nitrobenzoyl chlori 4-(Chlorocarbonyl)nitrobenzene, 4-(Chloroformyl)nitrobenzene The nitrobenzene forMyl chloride p-Nitro Benzoyl Chloride 4-Nitro Benzoyl Chloride paraNitro Benzoyl Chloride 4-NitrobenzoylChloride99% PNBC 4-Nitrobenzoyl 4-NitrobenzoylChloride> SKL748 TIANFUCHEM--122-04-3--4-Nitrobenzoyl chloride factory price 4-Nitrobenzoyl Chloride (PNBC) pure, 98% 122-04-3 112-04-3 O2NC6H4COCl NO2C6H4COCl Acid Halides UV-VIS Organic Building Blocks Carbonyl Compounds Building Blocks ACID CHLORIDE Amino Group Labeling Reagents for HPLC Exciton Chirality CD Method (for Hydroxyl Groups) UV Detection (HPLC Labeling Reagents) HPLC Labeling Reagents Enantiomer Excess & Absolute Conefiguration Determination Hydroxyl Group Labeling Reagents for HPLC Absolute Conefiguration Determination (Exciton Chirality CD Method) Acid Halides Carbonyl Compounds Organic Building Blocks Derivatization Reagents Derivatization Reagents HPLC UV-VIS Absolute Configuration Determination (Exciton Chirality CD Method) Amino Group Labeling Reagents for HPLC