1,2-Phenylenediacetic acid
- CAS No.
- 7500-53-0
- Chemical Name:
- 1,2-Phenylenediacetic acid
- Synonyms
- RARECHEM AL BO 0119;O-BENZENEDIACETIC ACID;2-Phenylenediacetic acid;O-PHENYLENEDIACETIC ACID;1,2-Benzenediacetic acid;BENZENE-1,2-DIACETIC ACID;1,2-PHENYLENEDIACETIC ACID;o-Phenylenebis(acetic acid);1,2-PhenylenediaceticAcid>o-Phenylenediacetic acid, 98+%
- CBNumber:
- CB2204020
- Molecular Formula:
- C10H10O4
- Molecular Weight:
- 194.18
- MDL Number:
- MFCD00004329
- MOL File:
- 7500-53-0.mol
- MSDS File:
- SDS
| Melting point | 150-152 °C (lit.) |
|---|---|
| Boiling point | 290.62°C (rough estimate) |
| Density | 1.2534 (rough estimate) |
| refractive index | 1.5430 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Needle-Like Crystalline Powder |
| pka | 3.90±0.10(Predicted) |
| color | Beige to beige-brown |
| BRN | 2616747 |
| InChI | InChI=1S/C10H10O4/c11-9(12)5-7-3-1-2-4-8(7)6-10(13)14/h1-4H,5-6H2,(H,11,12)(H,13,14) |
| InChIKey | MMEDJBFVJUFIDD-UHFFFAOYSA-N |
| SMILES | C1(CC(O)=O)=CC=CC=C1CC(O)=O |
| CAS DataBase Reference | 7500-53-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29173990 | |||||||||
| NFPA 704 |
|
1,2-Phenylenediacetic acid price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 131407 | 1,2-Phenylenediacetic acid 99% | 7500-53-0 | 5g | $61.4 | 2023-06-20 | Buy |
| TCI Chemical | P1052 | 1,2-Phenylenediacetic Acid >98.0%(HPLC)(T) | 7500-53-0 | 5g | $28 | 2025-07-31 | Buy |
| TRC | P319930 | 1,2-Phenylenediacetic acid | 7500-53-0 | 5g | $75 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK133996 | 1,2-Phenylenediacetic acid | 7500-53-0 | 25g | $133 | 2021-12-16 | Buy |
| AK Scientific | J56497 | o-Phenylenediaceticacid | 7500-53-0 | 5g | $27 | 2021-12-16 | Buy |
1,2-Phenylenediacetic acid Chemical Properties,Uses,Production
Chemical Properties
beige to beige-brown needle-like crystalline
Uses
1,2-Phenylenediacetic Acid has been used in the preparation of nanomolar inhibitors of cancer-relevant transcription factor STAT5b.
General Description
A coordination polymer with 1,2-Phenylenediacetic acid was synthesized and characterized by single crystal X-ray diffraction.
Synthesis
613-73-0
7500-53-0
The general procedure for the synthesis of 2,2'-(1,2-phenylene)diacetic acid from 1,2-phenylenediacetonitrile was as follows: 1,2-phenylenediacetonitrile (5.0 g) was dissolved in 50 mL of concentrated hydrochloric acid and heated and refluxed for 3 hours. After the reaction was completed, 30 mL of water was added and heating was continued overnight. The reaction mixture was cooled to room temperature and washed with ether. Subsequently, the organic layer was extracted twice with aqueous sodium carbonate. The aqueous layers were combined, acidified to pH 2-3 with hydrochloric acid and extracted with ether. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated to give 2,2'-(1,2-phenylene)diacetic acid as a light yellow solid in 56% yield with a melting point of 123-125 °C. The product was confirmed by 1H NMR (250 MHz, DMSO-d6): δ 3.58 (s, 4H), 7.20 (s, 4H), 12.34 (br s, 2H); 13C NMR (63 MHz, DMSO-d6): δ 37.1 (2C), 126.8 (2C), 130.6 (2C), 134.1 (2C), 172.4 (2C).
References
[1] Patent: WO2011/41349, 2011, A1. Location in patent: Page/Page column 19-20
[2] Chemische Berichte, 1884, vol. 17, p. 447
[3] Journal of the Chemical Society, 1907, vol. 91, p. 176
[4] Journal of the Chemical Society, 1923, vol. 123, p. 2075
[5] Recueil des Travaux Chimiques des Pays-Bas, 1923, vol. 42, p. 412
1,2-Phenylenediacetic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2955 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8829 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 1,2-Phenylenediacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-12 | 1,2-Phenylenediacetic acid
7500-53-0
|
US $5.00 / kg | 1kg | ≥99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2025-06-27 | 1,2-Phenylenediacetic acid
7500-53-0
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-05-26 | 1,2-Phenylenediacetic acid
7500-53-0
|
US $30.00-10.00 / kg | 10kg | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 1,2-Phenylenediacetic acid
7500-53-0
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 1,2-Phenylenediacetic acid
7500-53-0
- US $0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1,2-Phenylenediacetic acid
7500-53-0
- US $30.00-10.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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