Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Ramelteon-d5

Ramelteon-d5

Ramelteon-d5 Structure
Ramelteon-d5 structure
CAS No.
1134159-63-9
Chemical Name:
Ramelteon-d5
Synonyms
Ramelteon-d5;N-{2-[(8S)-1H,2H,6H,7H,8H-indeno[5,4-b]furan-8-yl]ethyl}(2H?)propanamide
CBNumber:
CB22104243
Molecular Formula:
C16H21NO2
Molecular Weight:
259.35
MDL Number:
MOL File:
1134159-63-9.mol
Last updated:2026-01-04 19:55:51
Product description Number Pack Size Price
Ramelteon-d5 ≥99% deuterated forms (d1-d5) 25420 500μg $215
Ramelteon-d5 ≥99% deuterated forms (d1-d5) 25420 1mg $409
RAMELTEON-D5 95.00% RDL0007100 5MG $498.27
Request For Quotation

Ramelteon-d5 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25420 Ramelteon-d5 ≥99% deuterated forms (d1-d5) 1134159-63-9 500μg $215 2023-01-06 Buy
Cayman Chemical 25420 Ramelteon-d5 ≥99% deuterated forms (d1-d5) 1134159-63-9 1mg $409 2023-01-06 Buy
American Custom Chemicals Corporation RDL0007100 RAMELTEON-D5 95.00% 1134159-63-9 5MG $498.27 2021-12-16 Buy
Product number Packaging Price Buy
25420 500μg $215 Buy
25420 1mg $409 Buy
RDL0007100 5MG $498.27 Buy

Ramelteon-d5 Chemical Properties,Uses,Production

Uses

Ramelteon-d5 is deuterium labeled Ramelteon. Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation[1][2].

IC 50

MT2; MT1

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Kato K, et al. Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology. 2005;48(2):301-310. DOI:10.1016/j.neuropharm.2004.09.007
[3] Mayer G, et al. Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia. Sleep. 2009;32(3):351-360. DOI:10.1093/sleep/32.3.351
[4] Hirai K, et al. Ramelteon (TAK-375) accelerates reentrainment of circadian rhythm after a phase advance of the light-dark cycle in rats. J Biol Rhythms. 2005;20(1):27-37. DOI:10.1177/0748730404269890
[5] Miyamoto M, et al. The sleep-promoting action of ramelteon (TAK-375) in freely moving cats. Sleep. 2004;27(7):1319-1325. DOI:10.1093/sleep/27.7.1319

Ramelteon-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

Ramelteon-d5 Suppliers

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39042 58
Adamas Reagent, Ltd. 400-6009262 16621234537 chenyj@titansci.com China 14101 59
Artis Biotech Co. Ltd. 19138486554; 18108108965 sales@artisbio.com China 2124 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
Hefei Molake Biotechnology Co., Ltd. 0551-66336380 18956014586 983438788@qq.com China 2312 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Hubei Xinyang Medical Technology Co., Ltd 15347293736 2853117764@yongstandards.com China 10000 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24963 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Adamas Reagent, Ltd. 59
Artis Biotech Co. Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
Hefei Molake Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Hubei Xinyang Medical Technology Co., Ltd 58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

View Lastest Price from Ramelteon-d5 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ramelteon-d5 pictures 2026-01-04 Ramelteon-d5
1134159-63-9
 US $3420.00-685.00 / mg 10g TargetMol Chemicals Inc.
  • Ramelteon-d5 pictures
  • Ramelteon-d5
    1134159-63-9
  • US $3420.00-685.00 / mg
  • TargetMol Chemicals Inc.

1134159-63-9(Ramelteon-d5)Related Search:

3-(6,7-Dibromo-2,3-dihydrobenzofuran-5-yl)propanoic Acid Ramelteon Impurity 14 (E)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)ethylamine 4-Hydroxy Ramelteon Ramelteon Metabolite M-II
PropanaMide, N-[2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)ethyl]- (R)-Ramelteon (S)-(+)-Ibuprofen Ramelteon Impurity 10 Ramelteon Impurity 1 HCl
Acetonitrile, (1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)-, (2E)- (R)-2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)acetic acid (S)-2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)acetic acid Ramelteon Impurity 6 Despropionyl Ramelteon Hydrochloride
Ramelteon Impurity 22 2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylaMine hydrochloride Ramelteon

1of4

Ramelteon-d5 N-{2-[(8S)-1H,2H,6H,7H,8H-indeno[5,4-b]furan-8-yl]ethyl}(2H?)propanamide 1134159-63-9 C16H16NO2D5