ChemicalBook >> CAS DataBase List >>4-Bromoanisole

4-Bromoanisole

4-Bromoanisole structure

CAS No.: 104-92-7

Chemical Name:: 4-Bromoanisole

Synonyms: 1-BROMO-4-METHOXYBENZENE;P-BROMOANISOLE;2-Bromoanisole,98%;4-Bromoanisole,98%;1-bromo-4-methoxy-benzen;4-Bromoanisole,1-Bromo-4-methoxybenzene;p-Bromanisole;p-bromoanisol;Anisyl bromide;p-bromo-anisol

CBNumber:: CB2223135

Molecular Formula:: C7H7BrO

Molecular Weight:: 187.03

MDL Number:: MFCD00000097

MOL File:: 104-92-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-10 10:27:08

Product description	Number	Pack Size	Price
4-Bromoanisole ≥99.0%	B56501	50g	$44
4-Bromoanisole ≥99.0%	B56501	100g	$58.9
4-Bromoanisole >97.0%(GC)	B0547	25g	$18
4-Bromoanisole >97.0%(GC)	B0547	100g	$34
4-Bromoanisole ≥99.0%	B56501	500g	$175
More product size

Request For Quotation

4-Bromoanisole Properties

Melting point	9-10 °C (lit.)
Boiling point	223 °C (lit.)
Density	1.494 g/mL at 25 °C (lit.)
refractive index	n20/D 1.564(lit.)
Flash point	202 °F
storage temp.	Store below +30°C.
solubility	Chloroform (Sparingly), Ethyl Acetate (Slightly)
form	Liquid
color	Clear colorless to slightly yellow
Water Solubility	immiscible
Merck	14,1428
BRN	1237590
Henry's Law Constant	1.1×10^-2 mol/(m³Pa) at 25℃, Pfeifer et al. (2001)
Dielectric constant	7.4000000000000004
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
InChI	1S/C7H7BrO/c1-9-7-4-2-6(8)3-5-7/h2-5H,1H3
InChIKey	QJPJQTDYNZXKQF-UHFFFAOYSA-N
SMILES	COc1ccc(Br)cc1
CAS DataBase Reference	104-92-7(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	U430F901J9
NIST Chemistry Reference	Benzene, 1-bromo-4-methoxy-(104-92-7)
EPA Substance Registry System	Benzene, 1-bromo-4-methoxy- (104-92-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315

Precautionary statements

P264-P270-P280-P301+P312-P302+P352-P332+P313

PPE

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Hazard Codes

Safety Statements

23-24/25

WGK Germany

RTECS

BZ8501000

TSCA

TSCA listed

HS Code

29093038

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Oral
Skin Irrit. 2

Toxicity

LD50 orl-mus: 2200 mg/kg GISAAA 44(12),19,79

NFPA 704

	0
1		0

4-Bromoanisole price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B56501	4-Bromoanisole ≥99.0%	104-92-7	50g	$44	2026-03-19	Buy
Sigma-Aldrich	B56501	4-Bromoanisole ≥99.0%	104-92-7	100g	$58.9	2026-03-19	Buy
TCI Chemical	B0547	4-Bromoanisole >97.0%(GC)	104-92-7	25g	$18	2026-03-19	Buy
TCI Chemical	B0547	4-Bromoanisole >97.0%(GC)	104-92-7	100g	$34	2026-03-19	Buy
Sigma-Aldrich	B56501	4-Bromoanisole ≥99.0%	104-92-7	500g	$175	2026-03-19	Buy

Product number	Packaging	Price	Buy
B56501	50g	$44	Buy
B56501	100g	$58.9	Buy
B0547	25g	$18	Buy
B0547	100g	$34	Buy
B56501	500g	$175	Buy

4-Bromoanisole Chemical Properties,Uses,Production

Chemical Properties

4-Bromoanisole is a colourless to pale yellow oily liquid with a pleasant smell similar to that of anise seed. Insoluble in water, soluble in ethanol, ether and chloroform. It is one of three isomers of bromoanisole, the others being 3-bromoanisole and 2-bromoanisole. It is the precursor to many 4-anisyl derivatives.

Uses

4-Bromoanisole finds application as an intermediate in synthetic chemistry. It is used in the preparation of aryl 1,3-diketones and ethyl 4-methoxycinnamate. It is a used as a brominating reagent. Further, it is used in Suzuki coupling reaction with phenylboronic acid as well as in Heck reaction.

Preparation

4-Bromoanisole is obtained by reacting p-bromophenol with dimethyl sulfate.

Definition

ChEBI: 4-bromoanisole is a monomethoxybenzene carrying a bromo substituent at position 4. It is a monomethoxybenzene and an organobromine compound.

Biological Functions

4-Bromoanisole is compound sometimes used in RNA extraction which serves to further eliminate DNA contamination. It interacts with genomic DNA(gDNA) and through a separation phase, it will be located in the organic layer instead of the aqueous layer (upper layer) containing the RNA extract.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 7429, 1994 DOI: 10.1016/0040-4039(94)85333-9
Synthesis, p. 868, 1986 DOI: 10.1055/s-1986-31813

General Description

4-Bromoanisole is a useful brominating reagent. It is formed as reaction product in the reaction between HOBr and anisole. Suzuki coupling of 4-bromoanisole with phenylboronic acid catalyzed by palladium pincer complexes has been studied. Heck Reaction of 4-bromoanisole with ethyl acrylates in room-temperature ionic liquids is reported to afford ethyl 4-methoxycinnamate.

Safety Profile

Moderately toxic by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic vapors of Br^-.

Purification Methods

Crystallise the anisole by repeated partial freezing, then distil it under reduced pressure. [Beilstein 6 III 741, 6 IV 1044.]

4-Bromoanisole synthesis

Synthesis of 4-Bromoanisole from Anisole

4-Bromoanisole Preparation Products And Raw materials

Raw materials

Extractant Anisole 4-Bromophenol Bromine Dimethyl ether

Dimethyl sulfate 2-Chloroanisole 2,4-DIBROMOANISOLE 2-Bromoanisole

1of2

Preparation Products

cis-Anethol 4-(IMIDAZOL-1-YL)PHENOL TRIS(4-HYDROXYPHENYL)PHOSPHINE OXIDE (4-METHOXYPHENYL)-BORANE 4-Methoxytriphenylmethyl chloride

5-Bromo-2-methoxyphenol 1-(5-Bromo-2-methoxy-phenyl)adamantane 4,4'-DIMETHOXYDIPHENYLAMINE 5-BROMO-3,3-DIMETHYL-2,3-DIHYDROBENZOFURAN 4-METHOXYPHENETHYL BROMIDE

(4-METHOXYPHENYLETHYNYL)TRIMETHYLSILANE& 4,4'-Dimethoxybiphenyl

1of3

4-Bromoanisole Suppliers

Global( 510)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	17259	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Yancheng Longshen Chemical Co.,Ltd.	+86-18352073383 +86-18352073383	sales@longshenchem.com	China	100	55
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Qingdao RENAS Polymer Material Co., Ltd.	+86-0532-86867058 +86-18562606086	sales@qdrenas.com	China	1066	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21591	55
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58

Supplier	Advantage
CD Chemical Group Limited	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Yancheng Longshen Chemical Co.,Ltd.	55
Hebei Chuanghai Biotechnology Co., Ltd	58
Qingdao RENAS Polymer Material Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Xiamen AmoyChem Co., Ltd	58

View Lastest Price from 4-Bromoanisole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-29	4-Bromoanisole 104-92-7	US $0.00 / KG	1KG	≥99%	30 Tons/Month	Yancheng Longshen Chemical Co.,Ltd.
2026-04-22	4-Bromoanisole 104-92-7	US $0.00 / kg	20kg	99%	20 tons	Qingdao RENAS Polymer Material Co., Ltd.
2026-03-20	4-Bromoanisole 104-92-7	US $10.00 / kg	1kg	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

4-Bromoanisole
104-92-7
US $0.00 / KG
≥99%
Yancheng Longshen Chemical Co.,Ltd.

4-Bromoanisole
104-92-7
US $0.00 / kg
99%
Qingdao RENAS Polymer Material Co., Ltd.

4-Bromoanisole
104-92-7
US $10.00 / kg
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Bromoanisole Spectrum

4-Bromoanisole(104-92-7)MS 4-Bromoanisole(104-92-7)¹HNMR 4-Bromoanisole(104-92-7)¹³CNMR 4-Bromoanisole(104-92-7)IR1 4-Bromoanisole(104-92-7)IR2 4-Bromoanisole(104-92-7)Raman

104-92-7(4-Bromoanisole)Related Search:

Anisole Thioanisole (Trifluoromethoxy)benzene Tetrabromobisphenol A bis(dibromopropyl ether) m-Anisyl alcohol

Decabromodiphenyl oxide 1,2-Dibromobenzene Anise oil Bromoxynil 4'-Bromopropiophenone

4-Methoxyphenol 2-Bromobenzonitrile 4-Methoxybenzyl alcohol 4-Bromobenzaldehyde 4-Methoxyphenylacetic acid

o-Anisaldehyde 1,3-Dibromobenzene 4-Methoxybenzoic acid

1of4

p-methoxyphenylbromide 2-Bromoanisole,98% 4-Bromomethoxybenzene 4-Methoxy-1-bromobenzene 4-Methoxybromobenzene 4-Methoxyphenyl bromide 4-methoxyphenylbromide Anisole, p-bromo- Anisyl bromide Benzene,1-bromo-4-methoxy- p-Anisyl bromide p-anisylbromide p-Bromanisole p-bromoanisol p-bromo-anisol p-Bromophenyl methyl ether para-BROMOANISOLE 4-BROMO ANISOLE 99%MIN Bromophenol methyl ether 4-Bromoanisole,98% 4-Bromoanisole,1-Bromo-4-methoxybenzene Of BroMoanisole p-BroMophenol Methyl ether 4-BroMoanisole, 98% 100ML 4-BROMOANISOLE FOR SYNTHESIS 100 ML 4-BROMOANISOLE FOR SYNTHESIS 250 ML 4-BroMoanisole >=99.0% The broMobenzene Methyl ether BROMOANISOLE(4-) 4-Bromoanisole≥ 99% (GC) 4-BROMO ANISOL 4-BROMOANISOLE 1-bromo-4-methoxy-benzen p-bromophenylmethylether p-Methoxybromobenzene p-Methoxyphenyl bromide 4-Bromoanisole > 4-Bromoanisole (p-Methoxyphenyl Bromide) 4-Bromoanisole,99% Para Bromo Anisole (PBA) (Campaign base) 4-Bromoanisole pure, 98% PARA BROMO ANISOLE/ ALKYL BROMIDE P-bromophenyl ether 4-Bromoanisole 98% For Synthesis p-Bromobenzylmethylether 1-BROMO-4-METHOXYBENZENE P-BROMOANISOLE 104-92-7 104-92-2 102-92-7 Building Blocks Organic Building Blocks Oxygen Compounds ARYL HALIDE Ethers Anisoles, Alkyloxy Compounds & Phenylacetates Bromine Compounds alkyl bromide