3,5-Bis(tert-butyl)benzaldehyde
- CAS No.
- 17610-00-3
- Chemical Name:
- 3,5-Bis(tert-butyl)benzaldehyde
- Synonyms
- 3,5-DI-TERT-BUTYL-BENZALDEHYDE;RARECHEM AQ A2 0001;3,5-Di-tert-butylbenzaldehyle;3,5-BIS(TERT-BUTYL)BENZLDEHYDE;3,5-BIS(TERT-BUTYL)BENZALDEHYDE;3,5-Di-tert-butylbenzaldehyde>3,5-Di-tert-butylbenzaldehyde 97%;3,5-BIS(TERT-BUTYL)BENZALDEHYDE 97%;3,5-Bis(tert-butyl)-1-formylbenzene;3,5-Bis(tert-butyl)benzaldehyde,97%
- CBNumber:
- CB2226101
- Molecular Formula:
- C15H22O
- Molecular Weight:
- 218.33
- MDL Number:
- MFCD00026298
- MOL File:
- 17610-00-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3,5-Di-tert-butylbenzaldehyde 97% | 574589 | 1g | $76.5 |
| 3,5-Di-tert-butylbenzaldehyde 97% | 574589 | 5g | $226 |
| 3,5-Di-tert-butylbenzaldehyde >97.0%(GC) | D4130 | 1g | $44 |
| 3,5-Di-tert-butylbenzaldehyde >97.0%(GC) | D4130 | 5g | $221 |
| 3,5-DI-TERT-BUTYLBENZALDEHYDE 95% | 60430 | 5G | $34 |
| More product size | |||
| Melting point | 85-89 °C(lit.) |
|---|---|
| Boiling point | 132°C/5mmHg(lit.) |
| Density | 0.9445 (rough estimate) |
| refractive index | 1.5410 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | White to Almost white |
| λmax | 296nm(CHCl3)(lit.) |
| InChI | InChI=1S/C15H22O/c1-14(2,3)12-7-11(10-16)8-13(9-12)15(4,5)6/h7-10H,1-6H3 |
| InChIKey | BRUITYMDHWNCIG-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1 |
| CAS DataBase Reference | 17610-00-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P271-P261-P280 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29122990 |
| Storage Class | 11 - Combustible Solids |
3,5-Bis(tert-butyl)benzaldehyde price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 574589 | 3,5-Di-tert-butylbenzaldehyde 97% | 17610-00-3 | 1g | $76.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 574589 | 3,5-Di-tert-butylbenzaldehyde 97% | 17610-00-3 | 5g | $226 | 2026-04-30 | Buy |
| TCI Chemical | D4130 | 3,5-Di-tert-butylbenzaldehyde >97.0%(GC) | 17610-00-3 | 1g | $44 | 2026-04-30 | Buy |
| TCI Chemical | D4130 | 3,5-Di-tert-butylbenzaldehyde >97.0%(GC) | 17610-00-3 | 5g | $221 | 2026-04-30 | Buy |
| AstaTech | 60430 | 3,5-DI-TERT-BUTYLBENZALDEHYDE 95% | 17610-00-3 | 5G | $34 | 2026-04-30 | Buy |
3,5-Bis(tert-butyl)benzaldehyde Chemical Properties,Uses,Production
Chemical Properties
off-white powder
Uses
3,5-Di-tert-butylbenzaldehyde may be used in the synthesis of the following:
- 5-p-pyridyl-15-(3,5-di-tert-butylphenyl)porphyrin via condensation reaction with 4-pyridinecarboxaldehyde and 2,2′-dipyrrylmethane
- 3,5-di-tert-butylphenyl-dipyrromethane via reaction with pyrrole in the presence of trifluoroacetic acid
- 3,5-di-tert-butyl-2-nitrobenzaldehyde via nitration reaction
Synthesis
22385-77-9
68-12-2
17610-00-3
1-Bromo-3,5-di-tert-butylbenzene (5.00 g, 18.57 mmol) was dissolved in tetrahydrofuran (THF, 50 mL) under nitrogen protection. The reaction mixture was cooled to -78°C. n-Butyllithium (2.5 M hexane solution, 22.29 mL, 55.72 mmol) was slowly added, keeping the temperature at -78°C. The reaction mixture was stirred for 30 min at -78°C. The reaction mixture was then stirred for 30 min at -78°C. Subsequently, N,N-dimethylformamide (DMF, 4.31 mL, 55.72 mmol) was added dropwise. The reaction mixture was slowly warmed to 0°C and stirred at this temperature for 2.5 hours. Upon completion of the reaction, the reaction was quenched by the addition of aqueous ammonium chloride solution (30 mL). The reaction mixture was extracted with ethyl acetate (EtOAc, 3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered, the filtrate collected and concentrated under reduced pressure. The residue was purified by fast column chromatography using a 0-10% ethyl acetate/petroleum ether gradient elution to afford 3,5-bis(tert-butyl)benzaldehyde (2.96 g, 73% yield) as a white solid.LC-ES/MS m/z 219 [M + H]+.
References
[1] Journal of the American Chemical Society, 2011, vol. 133, # 13, p. 4710 - 4713
[2] Patent: WO2013/66640, 2013, A1. Location in patent: Page/Page column 15
3,5-Bis(tert-butyl)benzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23653 | 75 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2501 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Synbest Biotech(Hangzhou) Co., Ltd | 86-571-88737065 | sales@synbestech.com | CHINA | 170 | 58 |
View Lastest Price from 3,5-Bis(tert-butyl)benzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | 3,5-Di-tert-butylbenzaldehyde
17610-00-3
|
$30.00 | 99.89% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | 3,5-Bis(tert-butyl)benzaldehyde
17610-00-3
|
$10.00 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2026-02-02 | 3,5-Bis(tert-butyl)benzaldehyde
17610-00-3
|
10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 3,5-Di-tert-butylbenzaldehyde
17610-00-3
- $30.00
- 99.89%
- TargetMol Chemicals Inc.
-
- 3,5-Bis(tert-butyl)benzaldehyde
17610-00-3
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3,5-Bis(tert-butyl)benzaldehyde
17610-00-3
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
