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ChemicalBook >> CAS DataBase List >>7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Structure
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER structure
CAS No.
16600-22-9
Chemical Name:
7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER
Synonyms
NSC 403048;MK075B byproduct;3-Carbethoxy-4-hydroxy-7-chloroquinoline;Ethyl7-chloro-4-hydroxy-3-quinolinecarboxylate;Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate;Ethyl 4-hydroxy-7-chloroquinoline-3-carboxylate;ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate;Ethyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylate;4-Hydroxy-7-chloroquinoline-3-carboxylic acid ethyl ester;7-chloro-4-oxo-1H-quinoline-3-carboxylic acid methyl ester
CBNumber:
CB2234544
Molecular Formula:
C12H10ClNO3
Molecular Weight:
251.67
MDL Number:
MFCD00438741
MOL File:
16600-22-9.mol
MSDS File:
SDS
Last updated:2026-05-28 00:00:15
Product description Number Pack Size Price
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate ≥95% OR183495 250mg $131
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate ≥95% OR183495 1g $327
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate 301324 100.00mg $104
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate 301324 250.00mg $139
Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate 301324 1.00g $341
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7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Properties

Melting point 296-298℃
Boiling point 366.8±37.0 °C(Predicted)
Density 1.386
storage temp. Sealed in dry,Room Temperature
pka 2.18±0.50(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H361-H341
Precautionary statements  P501-P202-P201-P280-P308+P313-P405
HS Code  2933499090

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR183495 Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate ≥95% 16600-22-9 250mg $131 2026-06-04 Buy
Apolloscientific OR183495 Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate ≥95% 16600-22-9 1g $327 2026-06-04 Buy
Matrix Scientific 301324 Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate 16600-22-9 100.00mg $104 2026-05-19 Buy
Matrix Scientific 301324 Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate 16600-22-9 250.00mg $139 2026-05-19 Buy
Matrix Scientific 301324 Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate 16600-22-9 1.00g $341 2026-05-19 Buy
Product number Packaging Price Buy
OR183495 250mg $131 Buy
OR183495 1g $327 Buy
301324 100.00mg $104 Buy
301324 250.00mg $139 Buy
301324 1.00g $341 Buy

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Uses,Production

Chemical Properties

Crystalline compounds. Melting point 297 ℃.

Uses

Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be used as an intermediate of chloroquine.

Synthesis

Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can be obtained by heating and condensing m-chloroaniline and triethyl orthoformate, then condensing with diethyl malonate with the participation of boron trifluoride, and finally heating and cyclizing in paraffin oil.

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Mineral oil N-2,4-DIMETHYLPHENYL-N'-METHYLFORMAMIDINE 3-Chloroaniline

Preparation Products

ETHYL 4,7-DICHLOROQUINOLINE-3-CARBOXYLATE

7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Moxin Chemicals 		+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
GIHI CHEMICALS CO.,LIMITED 		+86-571-86217390; +8618058761490 info@gihichemicals.com China 49938 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131956 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42934 64
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10266 58
SynAsst Chemical. 021-60343070 China 12740 55
Shanghai Worldyang Chemical Co.,Ltd. 021-021-56795766 sales@worldyachem.com China 9478 58
Supplier Advantage
Moxin Chemicals 		58
Alchem Pharmtech,Inc. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
GIHI CHEMICALS CO.,LIMITED 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Amadis Chemical Company Limited 		58
Shanghai Hanhong Scientific Co.,Ltd. 64
Hangzhou Sage Chemical Co., Ltd. 58
SynAsst Chemical. 55
Shanghai Worldyang Chemical Co.,Ltd. 58

View Lastest Price from 7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lenvatinib Impurity 80 pictures 2025-12-16 Lenvatinib Impurity 80
16600-22-9
 10mg 99%+ HPLC 1000 Moxin Chemicals

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7-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Ethyl-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylate 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, ethyl ester 3-Carbethoxy-4-hydroxy-7-chloroquinoline Ethyl 4-hydroxy-7-chloroquinoline-3-carboxylate 4-Hydroxy-7-chloroquinoline-3-carboxylic acid ethyl ester ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate Ethyl7-chloro-4-hydroxy-3-quinolinecarboxylate NSC 403048 Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate 7-chloro-4-oxo-1H-quinoline-3-carboxylic acid methyl ester MK075B byproduct 16600-22-9